Clinical trials: sponsored by University Hospital, Caen
Sleep Apnea, Arrhythmias, Cardiac
Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction
Little is known about potential relationships between sleep apnea, plasma aldosterone and diastolic dysfunction which is a very frequent finding among patients requiring permanent cardiac pacing.
- Conditions
- Sleep Apnea, Arrhythmias, Cardiac, Cardiac Diastolic Function, Hyperaldosteronism
- Trial name
- SAPAAD (NCT02751021)
- Testing
- pacemaker diagnostic algorithm, Attended cardiorespiratory sleep study
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Caen
Wart, Energy Medecine
Biofields Therapy on Warts
Traditionally, healers are willing to look after, two out of three French citizens have already appealed to them at least once during their lives.
- Conditions
- Wart, Energy Medecine, Magnetism
- Trial name
- MAGNETIK (NCT02773719)
- Testing
- True Biofield therapy, Fake Biofield therapy
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Caen
Depression, Schizophrenia
Repetitive Transcranial Magnetic Stimulation (rTMS) and P50 Evoked Potential Component
The repetitive transcranial magnetic stimulation (rTMS) is a recent technique that has demonstrated its efficiency in both depression and schizophrenia.
- Trial name
- rTMS-P50 (NCT01466439)
- Testing
- high-frequency of repetitive transcranial magnetic stimulation (rTMS), low frequency of repetitive transcranial magnetic stimulation (rTMS)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Type 1 Diabetes Mellitus Maturity Onset
Smartguard Use in Real Life : a Longitudinal Study in Patients With Type 1 Diabetes
The reference treatment of the type 1 diabetes is intensified insulin therapy by insulin pump. The CGM (continuous glucose monitoring) is a technology available for a decade, which allows the continuous measure of interstitial…
- Trial name
- Smartguard (NCT03047486)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Auditory Hallucinations in Patients With Schizophrenic Disorders
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled Study
Background: Repetitive transcranial magnetic stimulation (rTMS) is a recent therapeutic which has demonstrated its efficacy in the treatment of auditory hallucinations in patients with schizophrenic disorders.
- Trial name
- TMS-Hz (NCT01022489)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Type 2 Diabetes
Effects of Neuro-myo-electrical Stimulation on Insulin Sensitivity in Patients With Type 2 Diabetes
Type 2 diabetes is a major public health problem because of its increasing prevalence and morbidity and mortality that accompanies it.
- Trial name
- ELECTRODIAB (NCT02510521)
- Testing
- acute muscle exercise by NMES, daily workout sequence with NMES in one week, rest situation
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Vigilance and Simulated Driving After a Nap
The objective of this study is to assess the effectiveness of naps under different environmental conditions and a rest without nap, on driving, alertness and psychomotor performance.
- Trial name
- SOMBOX (NCT03978026)
- Testing
- Nap
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anesthesia, Atelectasis
Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit
The purpose of the study is to assess the optimal fraction of inspired oxygen (0.5 or 1) for extubation or removal of a supraglottic airway device after general anesthesia.
- Conditions
- Anesthesia, Atelectasis, Postoperative Complications, Hypoxemia
- Trial name
- EXTUBO2 (NCT04879290)
- Testing
- FiO2 0.5, FiO2 1
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Caen
Stress Disorders, Post-Traumatic
Stress and Emotional Memory
A broad group of disorders is associated with severe stress existence in children or adolescents. The most characteristic result, and one of the most serious being the state of post-traumatic stress disorder (PTSD), whose main…
- Trial name
- SEME (NCT02510755)
- Testing
- MRI
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Chronic Obstructive Pulmonary Disease (COPD), Decompensated COPD With (Acute) Exacerbation
Breathing-swallowing Interaction in Chronic Obstructive Pulmonary Disease Patients - Impact of Non Invasive Ventilation
In the investigators' knowledge there are no data about the impact of non invasive mechanical ventilation on the breathing-swallowing interaction.
- Trial name
- NCT01518075
- Testing
- Spontaneous Breathing, Non Invasive Mechanical Ventilation
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Squamous Cell Carcinoma of the Head and Neck
Nutrition and Life QUality Patients With Head and Neck Cancers
Malnutrition is currently a major factor of morbidity and mortality, which poses a major public health problem in developing countries but also, albeit to a lesser degree and for different reasons, for industrialized countries.
- Trial name
- NUQUE2 (NCT02510859)
- Testing
- Systematic nutritional consultation at home
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Caen
Cancer, Brain Tumors
Assessment of [18F]FLT-PET Imaging for Diagnosis and Prognosis of Brain Tumors
The primary objective of this study is to assess the efficacy of the radiopharmaceutical 3'-deoxy-3'-[F-18]fluorothymidine, [F-18]FLT, a tracor of cell proliferation, using Positron Emission Tomography (PET) imaging for the tumor…
- Trial name
- FLT (NCT00850278)
- Testing
- FLT-PET imaging
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Acute Lung Injury, Mechanical Ventilation
NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
- Trial name
- NCT00963066
- Testing
- PSV - pressure suppot ventilation, NAVA - Neurally Adjusted Ventilatory Assist, NAVA - EMG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Telangiectasia
Pilot Study to Evaluate the Interest of PDL in the Management of Telangiectasia of the Face and Neckline in Systemic Scleroderma
This single-center, prospective, open-label, quasi-experimental, intra-individual comparative study will include a consecutive cohort of 21 patients with diffuse or limited, minimally active scleroderma with 3 to 30 years of…
- Trial name
- PDL (NCT05036200)
- Testing
- pulsed dye laser
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Caen
Polyp of Large Intestine, Colorectal Neoplasms
Perioperative Hemodynamic Optimization Using the Photoplethysmography in Colorectal Surgery
The purpose of this study is to determine whether hemodynamic optimization with photoplethysmography (ClearSight, Edwards Lifesciences, Irvine, CA) during colorectal surgery could decrease the incidence of perioperative…
- Conditions
- Polyp of Large Intestine, Colorectal Neoplasms, Crohn Disease
- Trial name
- PANEX3 (NCT02343601)
- Testing
- Photoplethysmography
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Study Evaluating the Relevance and Reliability of Gastrointestinal Temperature Measurements From a New Device (E-celsius)
E-Celsius device used for measuring the gastrointestinal temperature is composed of an ingestible capsule measuring the temperature as well as a transportable module receiving data from the capsule.
- Trial name
- e-TEMP (NCT02910479)
- Testing
- E-Celsius thermometer, Rectal thermometer, Esophageal thermometer
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Validity of Somatosensori Remediation for Postural Control in the Treatment of Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
In the absence of a medical consensus, the current management of Ehlers-Danlos Syndrome hypermobility type (hEDS) remains very speculative That's why investigators want in this study to demonstrate the beneficial contribution of…
- Trial name
- VITALISED (NCT04020107)
- Testing
- Compressive garment and Somatosensori Remediation
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Heart Failure
Comparative Study of Cardiac Adrenergic Function Explored by I-123-MIBG and CZT Camera (D-SPECT) Versus Anger Camera in Patients With Heart Failure
Cardiological examination constitute one of the major directions in nuclear medicine for detection of myocardial ischemia in patients suspected of coronary disease.
- Trial name
- ADRECARD (NCT02515812)
- Testing
- I-123-MIBG, CZT Camera (D-SPECT), Anger Camera
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Caen
ACL Reconstruction, ACL Injury
Validity of the SHD-LESS Scale After ACL Reconstruction
After anterior cruciate ligament reconstruction (ACL-R), Single Hop for Distance (SHD) performance aids in decision-making, particularly for return-to-sport assessments.
- Trial name
- ACL-LESS (NCT06829849)
- Testing
- Landing error assessment during a SHD task using the SHD-LESS scale
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Chronic Renal Insufficiency, Peritoneal Dialysis
Apixaban in Subjects With Peritoneal Dialysis
The primary objective of this study is to assess the pharmacokinetics of a single oral dose of apixaban (5mg) in participants with dialysis peritoneal versus participants with normal renal function.
- Trial name
- ApiDP (NCT04006093)
- Testing
- Apixaban single dose 5mg
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Caen