Clinical trials: sponsored by University Hospital, Caen
Adult With Stroke and Olfaction's Complaint
REEDUCATION OF OLFACTORY DISORDERS AFTER A CEREBRAL VASCULAR ACCIDENT IN ADULTS
Study context: The literature identifies more and more research revealing olfactory disorders, with a high frequency after an acquired brain injury.
- Trial name
- RE-OLF (NCT04703218)
- Testing
- olfactory rehabilitation
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Caen
Stroke, Ischemic
N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE
The primary objective of the study is to assess the safety of N-Acetylcysteine as a thrombolytic agent in acute ischemic stroke, especially regarding the risk of hemorrhagic transformation.
- Trial name
- NAC-S (NCT04920448)
- Testing
- N-Acetyl cysteine
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Caen
Static and Dynamic Posture Standards
Posture Standards of a New Dynamic Platform
The objective is the determination of norms on healthy subjects, by age groups (20-29/30-39/40-49/50-59/60-69/70-79/80-89 years) for the posturological evaluation of four posture tests: the sensory organization test, the motor…
- Trial name
- VESTINORM (NCT05532176)
- Testing
- Posture standards
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Idiopathic Infantile Hypercalcemia - Severe Form
Vitamin D Analog in Vitamin D 24-hydroxylase Deficiency
Preclinical evaluation of a vitamin D analog for the treatment of vitamin D 24-hydroxylase using fibroblast from patients with CYP24A1 mutation.
- Trial name
- VaraD-Cell (NCT04987073)
- Testing
- skin biopsy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Diabetic Retinopathy, Artificial Intelligence
Screening for Diabetic Retinopathy in Pharmacies With Artificial Intelligence Enhanced Retinophotography
Diabetic retinopathy is frequent, potentially severe with visual threat, health costly and represents a major public health problem.
- Conditions
- Diabetic Retinopathy, Artificial Intelligence, Diabetes Mellitus
- Trial name
- DIABeyeIA (NCT05452993)
- Testing
- Analysed Retinophotography
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Caen
Schizophrenia; Psychosis
Efficacy of Maintenance Repetitive Transcranial Magnetic Stimulation (rTMS) in Auditory Verbal Hallucinations
Repetitive transcranial magnetic stimulation (rTMS) can alleviate persistent auditory verbal hallucinations (AVH) in schizophrenic patients, but the classical procedure with low-frequency stimulation for several weeks upon the…
- Trial name
- MAINSTIM (NCT05550155)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Idiopathic Bilateral Vestibulopathy
Idiopathic Bilateral Vestibulopathy: Peripheral Vestibular Disorders and Their Repercussions
The goal of this exploratory study is to gain a better understanding of the symptomatology of idiopathic bilateral vestibulopathy (IBV) by characterising as precisely as possible the type and intensity of each patient's…
- Trial name
- VBI (NCT06476587)
- Testing
- Assessment of postural stability and active motion perception, Cognitive tests, Eccentric axis rotation
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Body Schema
Body-environment Relationship Related Modified Gravity
The overall objective of this study is to better understand the relationship between the body and its environment, including cognitive performance, following repeated changes in gravity, including microgravity (0G) and modified…
- Trial name
- ENACT (NCT05531162)
- Testing
- Cognition and emotional neuropsychologicl evaluations
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Caen
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme
Multiple sclerosis (MS) is a central nervous system inflammatory disease that causes a chronic and progressive physical handicap.
- Trial name
- SEPIA (NCT03471338)
- Testing
- Cognitive rehabilitation, Standard Psychological care
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Fall
Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People
There are many epidemiological data on the relationship between the number or nature of psychoactive medications used and the risk of falling in elderly, but very little on the relationship between the amount of psychoactive…
- Trial name
- MEDIFALL (NCT05991037)
- Testing
- Blood sampling for psychoactive drugs dosage
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Caen
Mean Arterial Pressure
Perioperative Individualized Optimization of Mean Arterial Pressure in Cardiac Surgery
Neurologic and renal complications frequently occur after cardiac surgery. Acute renal failure following cardiac surgery increase the risk of chronic kidney disease, while postoperative neurological complications increased the…
- Trial name
- OPTIPAM (NCT05403697)
- Testing
- Individualized MAP
- Where
- France
- Volunteers
- 172 people
- Sponsor
- University Hospital, Caen
Hiv
DOR/TDF/3TC Switch With M184V/I in People With Controlled HIV (Drive Off-Road)
The goal of this pilot, phase 2, single-arm, clinical trial is to assess the antiretroviral combination Doravirine (DOR)/Lamivudine (3TC)/Tenofovir Disproxyl Fumarate (TDF) in participants with suppressed HIV who previously…
- Trial name
- DOR (NCT06034938)
- Testing
- Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO]
- Where
- 4 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Effects of Museum Visits on Neurocognitive Well-being
The effects of art on health and well-being have been the subject of increasing exploration in recent years. In 2019, the World Health Organization proposed a literature review analyzing the links between art, health (defined as…
- Trial name
- ABC (NCT06515041)
- Testing
- brain well-being
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Newborn; Infection
Pilot Study - Monitoring the Nasal Microbiome and Viral Respiratory Infections in Newborn Hospitalized in Neonatalogy.
The objective of our study is therefore to study the evolution of the respiratory microbiome of hospitalized newborns, its interaction with viral infections and their impacts on the evolution of newborns.
- Trial name
- NEONATMICROBIO (NCT06389383)
- Testing
- Nasal Swab
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Caen
Prolonged Grief Disorder
Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder
The goal of this clinical trial is to pilot the effectiveness of an 8-week standardized Mindfulness Training program to decrease the psychiatric and somatic symptoms of prolonged grief disorder (PGD) and to examine changes in…
- Trial name
- CALM-NiPS (NCT06017765)
- Testing
- Meditation Training, Waitlist
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
To Reduce Duration of Antibiotics Exposure in Patients With COPD Hospitalized in Intensive Care Unit With Pneumonia
An Antibiotic Protocol Guided by a Multimodal Approach in AECOPD With Pneumonia in Intensive Care
Investigators propose to conduct a multicenter, prospective, randomized, controlled, assessing the interests of an antibiotic protocol guided by the combined use of serum procalcitonin (PCT) and a broad-panel respiratory…
- Trial name
- BPCTréa2 (NCT06301841)
- Testing
- experimental
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Caen
Organ Failure, Multiple
Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs
This study will assess the impact of FTIRS typing on the spread of ESBL-E in intensive care units
- Trial name
- ECLA'IR (NCT05872152)
- Testing
- FTIR results
- Where
- France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Caen
Anorexia Nervosa, Exercise Therapy
Videoconferencing Adapted Physical Activity in Anorexia Nervosa: a Pilot Study
The primary objectives of the APAREXIM'Pilot study are to evaluate the short- and medium-term effects of a live supervised Adapted Physical Activity (APA) program via videoconferencing on: Feasibility and acceptability of APA via…
- Conditions
- Anorexia Nervosa, Exercise Therapy, Videoconferencing
- Trial name
- APAREXIM-P (NCT05770089)
- Testing
- Adapted Physical Activity (APA)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Prostate Cancer
Impact of New Hormonotherapy Drugs in Prostatic Cancer on the Risk of Cardiovascular Events : a Pharmacoepidemiology Study Using the French Health Care Claims Database
In prostate cancer, whether advanced or localized, hormone therapy is a key treatment. These therapies work by lowering male hormone levels to slow the growth of cancer.
- Trial name
- NCT06902441
- Where
- France
- Volunteers
- 52,000 people
- Sponsor
- University Hospital, Caen