Clinical trials: sponsored by University Hospital, Caen
Aortic Aneurysm, Athlete
Prevalence of Ascending Aortic Dilation in Sports Medicine
This study aims to assess the prevalence of ascending aortic dilation in athletes from the general population undergoing routine sports medicine evaluation.
- Trial name
- PRAADS (NCT07050953)
- Testing
- focused cardiac ultrasound
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Acquired Brain Injury Including Stroke
Prescription Patterns of Antidepressants, Analgesics, and Antiepileptics Drugs in Adult With Acquired Brain Injury
Acquired brain injury (ABI), primarily caused by stroke and traumatic brain injury (TBI), leads to severe disabilities and requires complex pharmacological management during post-acute rehabilitation.
- Trial name
- PRES'SMR (NCT06983314)
- Testing
- Observation
- Where
- France
- Volunteers
- 201 people
- Sponsor
- University Hospital, Caen
Fabry Disease
Aortic Dimensions in Patients With Fabry Disease
We will conduct a retrospective study aiming to define the characteristics, determinants, and progression of ascending aortic dilatation in adults with Fabry disease, using echocardiography and/or cardiac MRI
- Trial name
- DATA-Fab (NCT06956573)
- Testing
- aorta imaging
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Cerebral Aneurysm Unruptured
Impact of Life-size 3D Model on Patient Anxiety During Intracranial Aneurysms Embolization in Interventional Neuroradiology.
Intracranial aneurysm is a malformation of the cerebral arteries, identifying with a focal dilatation of the wall of an intracranial artery.
- Trial name
- ANXIFLOW (NCT06914414)
- Testing
- Using the flow model in cerebral aneurysm embolization
- Where
- France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Caen
Cardiac Sreening, Soccer Referees
Systematic Transthoracic Echocardiographic Screening in Amateur Football Referees
This retrospective study aims to evaluate the prevalence of cardiac abnormalities detected by transthoracic echocardiography (TTE) in amateur football referees as part of a systematic cardiovascular screening program.
- Trial name
- NCT06906484
- Testing
- echocardiography
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Neurodevelopmental Disorders, Child Behavior
Neurodevelopmental Outcome After Prenatal Anesthesia
In 2016, the US Food and Drug Administration raised concerns about the potential negative effects of anesthesia exposure on neurodevelopment in children during pregnancy or before the age of three.
- Trial name
- NCT06052878
- Testing
- Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF), Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
- Where
- France
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Porto-Sinusoidal Vascular Disease
Risk Factors for Portosinusoidal Vascular Disease in Kidney Transplant Recipients:
To look for the factors of exposure present prior to the onset of Porto-Sinusoidal Vascular Disease (PSVD) and which can lead to the occurrence of PSVD after renal transplantation, and therefore to consider the identification of…
- Trial name
- TRANSVAS (NCT05388409)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Caen
Sport Injury, Shoulder Injuries
Shoulder Muscle Imbalance as a Risk for Shoulder Injury in Elite Adolescent Badminton Players
Background: To assess the impact of pre-season clinical measures and rotator muscles strength on the risk of significant shoulder injury (SSI) in elite adolescent badminton players Design: Prospective cohort study Participants…
- Trial name
- BADIRMS (NCT04361539)
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Achilles Tendinopathy, Calf Injury
Longitudinal Changes in Achilles Tendon and Medial Gastrocnemius Muscle Architecture During a 156-km Ultradistance Trail Running Event
This study aimed to assess the longitudinal changes in triceps surae muscle-tendon architecture to an ultra distance trail running.
- Conditions
- Achilles Tendinopathy, Calf Injury, Sport Injury, Lower Limb Injury
- Trial name
- Trailstiff (NCT06297317)
- Testing
- Ultrasound measurement of triceps surae muscle-tendon architecture
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Caen
Leadless Pacemaker, Same-day Discharge
Vascular Access for Minimally-invasive Leadless Pacemaker Implantation Through the Right Jugular routE
Leadless pacemakers (LP) are associated with a lower risk of revision compared with transvenous pacemakers. However, LPs implantation is associated with a 0.6% risk of complication at the femoral vein puncture site (e.g.
- Trial name
- VAMPIRE (NCT06455566)
- Testing
- Leadless pacemaker implantation through right internal jugular vein
- Where
- 13 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Transcatheter Aortic Valve Replacement
Short Versus Long Antiplatelet Therapy After TAVI
The goal of this clinical trial is to learn if reducing the duration of treatment by aspirin to 3 months (short treatment regimen) after percutaneous aortic valve replacement is as safe and efficient as the routine lifetime…
- Trial name
- SOLOTAVI (NCT06518317)
- Testing
- Aspirin
- Where
- France
- Volunteers
- 1,400 people
- Sponsor
- University Hospital, Caen
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD
Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPD
Introduction Chronic obstructive pulmonary disease (COPD) is a common condition and the fourth leading cause of death worldwide.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD, Hypercapnic Respiratory Failure, COPD
- Trial name
- NIV-ICU (NCT06888180)
- Testing
- Non interventional study
- Volunteers
- 976 people
- Sponsor
- University Hospital, Caen
Atezolizumab and Bevacizumab in Hepatocellular Carcinoma
Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
In France primary liver cancers (PLC) is the fourth leading cause of cancer-related death in men, and the seventh in women. The number of new cases per year is predicted to increase by 26.5% between 2020 and 2040.
- Trial name
- ABCHCaen (NCT06416683)
- Where
- France
- Volunteers
- 109 people
- Sponsor
- University Hospital, Caen
Tendon Injuries, Muscle Tightness
Reliability of the Passive Properties of the Calf Muscles in Healthy Subjects Assessed Using Isokinetic Device
The investigators designed this study to determine the test-retest reliability of the viscoelastic passive properties of the calf muscles assessed using isokinetic device in flexed and extended knee position.
- Trial name
- ISOSTIFF (NCT04191759)
- Testing
- Test-Retest reproducibility
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hypothermia Due to Cold Environment
Thermoregulation During a 25-km Open Water Race
Open water swimming is a swimming discipline which takes place in outdoor water such as open oceans, lakes, and rivers. Elite swimmers are exposed to hypothermia when swimming in cold water, especially in long duration races…
- Trial name
- THERMO25 (NCT04460339)
- Testing
- Swimming participants in the 25-km
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Caen
Prescription, Physical Activity
Implementation and Effectiveness of a Community-based Exercise on Prescription Program for Adults With Chronic Diseases
The objectives were (1) to evaluate the characteristics of the patients referred, and (2) the effect of a community-based Exercise on Prescription program on their physical capacities and their quality of life.
- Conditions
- Prescription, Physical Activity, Chronic Disease
- Trial name
- SSOCaen (NCT04919889)
- Testing
- Exercise prescription
- Where
- France
- Volunteers
- 330 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injuries, Muscle Weakness
Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction
Anterior cruciate ligament (ACL) tear is a frequent and devastating injury in sport, especially in pivoting-contact disciplines.
- Trial name
- FoVeA (NCT05712109)
- Testing
- Follow-up after Anterior cruciate ligament reconstruction
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Caen
ACL Injury, Knee Injuries
Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of…
- Conditions
- ACL Injury, Knee Injuries, Muscle Weakness
- Trial name
- PREDICT-ACLv2 (NCT05897970)
- Testing
- Return-to-sport (RTS) follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Portal Vein Thrombosis, Local Cause
Risk Factors for Recurrence of Thrombosis or Thrombotic Extension, in the Event of Acute Non-cirrhotic Portal Vein Thrombosis Secondary to a Local Cause.
In case of acute portal vein thrombosis (PVT) prothrombotic factors are identified in about 60% of cases, while a local condition is present in 30% of cases.
- Trial name
- LOCAPORT (NCT05360641)
- Where
- France
- Volunteers
- 154 people
- Sponsor
- University Hospital, Caen