Clinical trials: sponsored by University Hospital, Caen
Sport Injury
Epidemiology of Injuries in Elite Badminton Players: a Prospective Study
Objective: To determine the incidence and characteristics of injuries in elite badminton players over a competitive season. Design: 12-months prospective cohort study Setting: The French National Institute of Sport, Expertise…
- Trial name
- BADINSEP (NCT04181242)
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hypothermia, Accidental, Cold Water Swimming
Core Temperature Afterdrop in Cold-water Swimming
A significant risk associated with hypothermia during exercise in a cold environment is the core temperature (T°core) afterdrop, which corresponds to a continuous fall in T°core during rewarming after hypothermia.
- Trial name
- THERMOCOLD (NCT05409560)
- Testing
- Swimming participants in the 6-hour cold water swim
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Proton Pump Inhibitor Adverse Reaction, Delirium
Delirium Related to Proton Pump Inhibitors Use
Delirium is a frequent and severe condition, especially in old adults. Its occurrence is due to a drug in 30% of cases. In 2009, the French national health authority (Haute Autorité de Santé) mentioned proton pump inhibitors…
- Conditions
- Proton Pump Inhibitor Adverse Reaction, Delirium, Hyponatremia
- Trial name
- NCT05815550
- Testing
- PPI
- Where
- France
- Volunteers
- 19,081 people
- Sponsor
- University Hospital, Caen
Pressure Ulcers Prevention in Prone Positioning in Intensive Care
Pressure Sore Prevention Strategy for the Prone Position
The aim of this clinical trial is to determine whether 5-layer hydrocellular dressings are effective in preventing the development of pressure sores during prone positioning in the intensive care unit.
- Trial name
- DERM-H-PROTECT (NCT06442657)
- Testing
- Hydrocellular dressing, Hydrocolloids dressing
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Caen
Binge Drinking, Alcohol Drinking
Alcohol Consumption, Intention Implementation and Mindfulness Meditation (ADUC-Volet 3 " Prevention ")
The emergence of new problematic alcohol consumption practices among young people requires new dynamics in prevention strategies.
- Trial name
- ALCOMEDIIT (NCT05565989)
- Testing
- MBM and II, MI
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Aged Patients Treated for Cancer in Outclinics
Falls Among the Older Patients Treated for Cancer in Normandy's Outclinics: Screening and Prevention
The French Plan National AntiChute (published on February 21, 2022) and international recommendations on falls prevention (Age Ageing,September 2022) recommend identifying the risk of falling in people aged 65 and over, at least…
- Trial name
- CHUPACHOUP (NCT06504628)
- Testing
- screening risk for falling and identifiy the risk level low-intermediate-high, 3 mnth-follow-up
- Where
- 10 sites in France
- Volunteers
- 328 people
- Sponsor
- University Hospital, Caen
Type B Aortic Dissection
Study of Prognostic Factors in Aortic Dissection Type B
Clinical outcomes of chronic type B aortic dissections are unknown, especially in case of false lumen expansion and risk of rupture. Data of literature give us some indications about prognosis.
- Trial name
- TEDAC (NCT01984905)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Aortic Stenosis
General Anesthesia Versus Loco-Regional Anesthesia for Transcarotid Trancatheter Aortic Valve Replacement
Transcarotid transcatheter aortic valve replacement (Transcarotid TAVR) has been increasingly used as an alternative to the transfemoral approach.
- Trial name
- GALATTAVI (NCT06870734)
- Volunteers
- 44 people
- Sponsor
- University Hospital, Caen
Adult Acute Myeloid Leukemia
Relation Between Venetoclax Plasma Concentration and Remission in Adults with Acute Myeloid Leukemia (PREDICLAX)
Background: In combination with hypomethylating drugs, venetoclax has recently changed the therapeutic management of patients with newly diagnosed acute myeloid leukemia (AML) for whom standard induction chemotherapy was not an…
- Trial name
- NCT06045819
- Testing
- Blood sampling for venetoclax drug dosage (venous puncture)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Amyloidosis Transthyretin
Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis
Introduction: Transthyretin cardiac amyloidosis (ATTR) is an important cause of heart failure. Cardiac planar radionuclide imaging using 99mTc-labeled bone seeking radiopharmaceuticals is used as a noninvasive diagnostic…
- Trial name
- REMOD-TTR (NCT04535349)
- Testing
- Whole-body & CZT bone tracer imaging (SPECT)
- Where
- 2 sites in France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Caen
Heart Failure, Cancer, Therapy-Related
Identification of Anticancer Drugs Associated With Cancer Therapy-related Cardiac Dysfunction: a Pharmacovigilance Study
Therapeutic advances have significantly improved the survival of patients with cancer. However, these novel therapies are associated with a concomitant increase in the prevalence of toxicity, including cardiovascular…
- Trial name
- NCT06268535
- Testing
- Cancer therapy with FDA and/or European Medicines Agency approval on the 30th September 2023
- Where
- France
- Volunteers
- 36,580,288 people
- Sponsor
- University Hospital, Caen
Adverse Effects of Medical Drugs
Adverse Drug Reactions to Cancer Therapies in Patients with Depression: Insights from VigiBase
Importance: Depression is prevalent among oncology patients and may influence the perception, reporting, and severity of adverse events (AEs) related to cancer therapies.
- Trial name
- NCT06801158
- Testing
- use of anticancer drugs in monotherapy or in combination therapy
- Where
- France
- Volunteers
- 8,804,863 people
- Sponsor
- University Hospital, Caen
Subarachnoid Hemorrhage
3D Contrast Enhanced Acoustic Perfusion Imaging in Adult After Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke, with three major complications : early brain injury (EBI), vasospasm and delayed cerebral ischemia (DCI).
- Trial name
- ESRIR (NCT06793839)
- Testing
- Transcranial Enhanced Ultrasonography localizing microscopy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Developing a Consensus Framework to Standardize Isokinetic Testing Data Reporting
Standardizing Reporting Practices for Isokinetic Testing: a Delphi Study
Isokinetic testing plays a crucial role in research and clinical practice, particularly for evaluating muscle strength, functional performance, and imbalances between muscle groups in fields such as rehabilitation, sports…
- Trial name
- NCT06733116
- Testing
- Delphi method survey
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anesthesia, Anesthesia Complication
Preoperative Blood Volume Optimization Using Transthoracic Echocardiography
Immediately following the induction of general anesthesia, arterial hypotension may occur with an incidence of about 40% in patients classified as ASA 3 or 4.
- Conditions
- Anesthesia, Anesthesia Complication, Anesthesia Induction, Arterial Hypotension
- Trial name
- EchOptimal (NCT06639737)
- Testing
- preoperative stroke volume optimization, Post induction stroke volume optimization
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Glioma, miRNA
Monitoring of Patients With Low-grade Gliomas Using Circulating miRNA
With around 3,400 cases per year in France, diffuse gliomas are the most common primary tumours of the central nervous system. Their grade varies from 2 to 4.
- Conditions
- Glioma, miRNA, Low-grade Glioma, Biomarkers
- Trial name
- GLIBAMIR (NCT06610851)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Acute Respiratory Distress Syndrom
Selective Lung Recruitment in Moderate to Severe ARDS : a Pilot Study
Acute respiratory distress syndrome (ARDS) is an acute condition affecting the lung after clinical aggression ( infectious process, pancreatitis, acute inflammatory event).
- Trial name
- SRIMSA (NCT06609629)
- Testing
- Selective lung recruitment
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Deep Vein Thrombosis
Diagnostic Performance of General Practitioners in Compression UltraSound
The objective of this study is to evaluate the diagnostic efficiency of general practitioners for the diagnosis of proximal deep vein thrombosis of the lower limbs compared with whole-leg ultrasound with Doppler performed by the…
- Trial name
- GPCUS (NCT05550038)
- Testing
- Compression ultrasound
- Where
- 19 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Alzheimer Disease, Semantic Dementia
Memory and Social Interactions
Memory and social interaction are intimately linked. On the one hand, social interaction is a privileged context for learning, and on the other hand, appropriate social interactions involve remembering the partners encountered…
- Trial name
- MEM&SO (NCT05800028)
- Testing
- Learning new information
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Genital Prolapse, Pessary
Pessary Satisfaction Criteria for Urogenital Prolapse
Genital prolapse is a common pathology with a prevalence ranging from 2.9 to 11.4% or 31.8% to 97.7%, depending on whether a questionnaire or clinical examination is used.
- Conditions
- Genital Prolapse, Pessary, Satisfaction
- Trial name
- PeSaCUP (NCT03615872)
- Testing
- pessary use
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen