Clinical trials: sponsored by University Hospital, Geneva
Body Composition, Running Performance
Does Body Composition Predict Running Time?
Several studies performed in elite endurance athletes have shown that running performance may be determined by a low fat mass in the overall population.
- Trial name
- NCT03400761
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Pain
Catheter Orifice Configuration (Six-hole Versus End-hole) on Post-operative Analgesia After Total Knee Arthroplasty.
Multiorifice catheters have been shown to provide superior analgesia and significantly reduce local anesthetic consumption compared with end-hole catheters in epidural studies.
- Trial name
- NCT03376178
- Testing
- lidocaine and ropivacaine injection through catheters
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University Hospital, Geneva
Acute Respiratory Failure
New Indirect Calorimetry Device for Energy Expenditure Measurement
Energy expenditure (EE) in critically ill patients is highly variable depending on the initial severity of the disease and treatments. Clinicians need to measure EE by indirect calorimetry (IC) to optimize nutritional support.
- Trial name
- ICALIC (NCT02024958)
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Geneva
Intensive Care Unit Patients
Prognosis Value of Bioimpedance Analysis (BIA) Phase Angle at Admission in Intensive Care Unit (ICU) Patients
Critically ill patients feature a loss of fat-free mass (FFM) up to 440 g/day, which is associated with increased morbidity and prolonged recovery.
- Trial name
- PAP (NCT01907347)
- Where
- 10 sites in Belgium, Brazil and 7 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Obesity, Non-alcoholic Fatty Liver Disease (NAFLD)
Dietary Intervention and Intestinal Microbiota in Non-alcoholic Fatty Liver
In patients with NAFLD/NASH, changes in liver lipid composition and function tests following a short dietary intervention are associated with changes in gut microbiota
- Trial name
- NCT01477307
- Testing
- Hypocaloric diet
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Loss of Consciousness
Sufentanil Bispectral Index Elderly
We compared BIS values during propofol stepwise induction with or without concomitant sufentanil in patients ≥ 65 years .
- Trial name
- NCT02831101
- Testing
- Sufentanil
- Volunteers
- 71 people
- Sponsor
- University Hospital, Geneva
Carotid Stenosis
Microembolisation After Carotid Revascularisation
Microembolisation identified on diffusion-weighted magnetic resonance imaging (DW-MRI) is recognized as an important outcome measure for carotid revascularization procedures such as carotid stenting (CAS) or carotid…
- Trial name
- NCT03303430
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University Hospital, Geneva
Attempted Vaginal Delivery After a Cesarean Section
A Specific Cervicograph for Women Attempting at Vaginal Delivery After Cesarean Section
The main objective is to evaluate a specific cervicograph (the graph describing the cervical dilation, included in the partograph) for pregnant women with an history of cesarean section, to improve the management of labor for…
- Trial name
- NCT03298594
- Testing
- specific cervicograph
- Volunteers
- 135 people
- Sponsor
- University Hospital, Geneva
Sleep, Intensive Care Unit Syndrome
Sleep Bundle for Improving Sleep in ICU Patients
Summary of the project : Lack or disturbances of sleep are major problems in patients staying in intensive care unit (ICU) due to the particular environment.
- Trial name
- NCT03247062
- Testing
- Quality improvement - sleep bundle
- Volunteers
- 130 people
- Sponsor
- University Hospital, Geneva
Emergencies, Triage
Impact of a Triage Liaison Physician
Due to an increasing number of patients admitted in emergency departments, many patients cannot be evaluated immediately after their admission. The function of "triage liaison physician" was introduced in Spring 2015.
- Trial name
- NCT02980159
- Testing
- Triage liaison physician
- Where
- Switzerland
- Volunteers
- 69,893 people
- Sponsor
- University Hospital, Geneva
Pain, Acute, Emergencies
Pain Evaluation and Treatment in the Emergency Department
All patients admitted in Geneva University Hospitals (GUH) emergency department (ED) are triaged using the Swiss Emergency Triage Scale (SETS), a 4-level symptom-based triage scale.
- Trial name
- NCT02980172
- Testing
- Pain evaluation
- Where
- Switzerland
- Volunteers
- 31,942 people
- Sponsor
- University Hospital, Geneva
Emergencies, Diagnostic Imaging
Abdominal Plain X-ray in the Emergency Departement
There are only few recognized indications for the realization of plain abdominal X-rays in the emergency departement. The objective of this study is to explore the reasons for abdominal plain X-rays prescription in the Emergency…
- Conditions
- Emergencies, Diagnostic Imaging, Abdomen, Acute
- Trial name
- NCT02980081
- Testing
- abdominal plain x-ray
- Where
- Switzerland
- Volunteers
- 1,997 people
- Sponsor
- University Hospital, Geneva
Abdominal Pain
Triage of Abdominal Pain in the Emergency Department
The investigators aim to evaluate in a retrospective study the performance of the Swiss Emergency Triage Scale to identify at the door of the Emergency Department patients requiring emergent intervention.
- Trial name
- NCT02064127
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Geneva
Parkinson Disease
DAT SPECT and Procedural Motor Skills in Parkinson's Disease
Patients with Parkinson's disease (PD) are known to be affected by subtle cognitive impairment early in the disease course, mostly in the executive field.
- Trial name
- NCT03076307
- Testing
- Procedural Motor Skills with mirror-drawing of figures
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Gestational Diabetes
Evaluation of Exercise, in Addition to Diet, in Women With Gestational Diabetes
The main objective is to evaluate the effect of therapeutic exercise program on blood glucose regulation in women with gestational diabetes mellitus (GDM) who are assigned to diet-and-exercise, compared to diet only (usual…
- Trial name
- NCT03174340
- Testing
- Exercise
- Volunteers
- 109 people
- Sponsor
- University Hospital, Geneva
Anemia, Postoperative Blood Loss
HepciFer Study: Hepcidin Overexpression After Hepatectomy : Does Iron Supplementation Make Sense ?
Hepcifer Trial is designed to assess the value of iv iron administration immediately after liver surgery and consequences of inflammation on iron balance. Fifty patients will be randomized in two treatment groups.
- Trial name
- HepciFer (NCT02631980)
- Testing
- IV iron
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Urinary Tract Infections, Cystitis
Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women
Developed before the establishment of a structured process for drug assessment, nitrofurantoin is now being prescribed frequently given the rise in multi-resistant gram-negative pathogens.
- Trial name
- AIDA-WP2 (NCT01966653)
- Testing
- nitrofurantoin, fosfomycin
- Where
- 3 sites in Israel, Poland and 1 more
- Volunteers
- 600 people
- Sponsor
- University Hospital, Geneva
Pharyngitis
Comparison of Two Rapid Antigen Detection Tests for the Detection of Group-A Streptococcal Pharyngitis in Children
Group A streptococcal (GAS) pharyngitis in children represents a frequent diagnostic challenge in pediatric emergency departments, since isolated signs and clinical prediction rules are insufficient to accurately discriminate…
- Trial name
- NCT03099018
- Testing
- Sofia Strep A FIA
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Acute Pain
Pain Relief in the Emergency Department Waiting Room: a Prevalence Study
Pain in the emergency room is under documented and pain relief suboptimal. Data on nurse driven analgesia in emergency department waiting rooms is lacking.
- Trial name
- NCT03115684
- Volunteers
- 2,371 people
- Sponsor
- University Hospital, Geneva
Healthy
Dose Adaptation to Offset the Interaction Between Ticagrelor and Ritonavir by Population-based PK Modeling
Ticagrelor is a new generation antiplatelet agent with higher efficacy as compared to clopidogrel and prasugrel in treatment of patients with moderate and high ischemic risks.
- Trial name
- NCT02435563
- Testing
- ticagrelor 180 mg administrated alone, Ticagrelor adjusted dose + ritonavir 100mg
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva