Clinical trials: sponsored by University Hospital, Geneva
Obesity, Bariatric Surgery Candidate
Micro-nutritional Status and Gut Microbiota in Morbidly Obese Patients Before and After Gastric Bypass
An intervention study design in 90 obese patients will be used. Nutritional, metabolic and psychological status as well as gut microbiota will be evaluated before gastric bypass and 6 months post surgery.
- Trial name
- NCT03029572
- Testing
- Diet supplementation, Bariatric surgery
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University Hospital, Geneva
Undernutrition
The ONSHUG Survey : A Quality Care Programme
Hypothesis : At hospital discharge for home, the medical prescription of ONS according to the official criteria of SSNC and the legal regulations (completed prescription according to health's insurance and homecare delivery)…
- Trial name
- NCT02476110
- Testing
- Oral nutritive supplements
- Where
- Switzerland
- Volunteers
- 416 people
- Sponsor
- University Hospital, Geneva
Undernutrition
Assessment of Food Intake in Hospitalized Patients
Food provision and consumption were assessed for all hospitalized patients over a 24h-period survey. This study is a part of a control quality programme and is performed every 4 years since 1999.
- Trial name
- UN+ (NCT02463565)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 4,152 people
- Sponsor
- University Hospital, Geneva
Hemorrhagic Disorders
Standardisation of Investigations of Mild Bleeding Disorders
Observational study aimed at evaluating the clinical impact of a standardised diagnostic procedure for the investigation of patients with suspected mild bleeding disorder (MBD).
- Trial name
- MBD (NCT02329899)
- Testing
- Second step of investigations
- Where
- Switzerland
- Volunteers
- 208 people
- Sponsor
- University Hospital, Geneva
Muscle Weakness, Gait, Unsteady
High Intensity Interval Training in Geriatrics
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
- Trial name
- HIITERGY (NCT02318459)
- Testing
- high intensity interval training-HIIT, Traditionnal group rehabilitation
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Physical Function, Cognitive Function
Physical Exercise and Jaques-Dalcroze Eurhythmics: Effects on Physical and Cognitive Functions, and Falls in Seniors
The purpose of this study is to evaluate the efficacy and the possible mechanisms underlying music-based multitask training (i.e., Jaques-Dalcroze eurhythmics) in older people, compared to multicomponent exercise training.
- Conditions
- Physical Function, Cognitive Function, Falls
- Trial name
- EPHYCOS (NCT01811745)
- Testing
- Jaques-Dalcroze eurhythmics training, Multicomponent exercise training
- Where
- Switzerland
- Volunteers
- 142 people
- Sponsor
- University Hospital, Geneva
Stroke
Neurofeedback Training of Alpha-band Coherence After Stroke
Background: The technology of brain-computer interfaces (BCI) enables the monitoring of brain activity and the generation of a real-time output about specific changes in activity patterns.
- Trial name
- NCT02223910
- Testing
- Neurofeedback training of functional connectivity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Visceral Leishmaniasis, Human African Trypanosomiasis
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)
Tropical fevers have been a diagnostic challenge from the antiquity. Nowadays, despite the availability of good diagnostic capacities, undifferentiated febrile illnesses continue to be a thorny problem for travel physicians.
- Conditions
- Visceral Leishmaniasis, Human African Trypanosomiasis, Enteric Fever, Melioidosis
- Trial name
- NCT01766830
- Testing
- rk28 ICT, IT LEISH (rK39), Immunochromatographic HAT test
- Where
- 7 sites in Cambodia, Democratic Republic of the Congo and 2 more
- Volunteers
- 1,927 people
- Sponsor
- University Hospital, Geneva
Human Papilloma Virus Infection, Cervical Intraepithelial Neoplasia Grade 2/3
The HPV Self-test as a Test of Cure in Madagascar
The purpose of this study is to find out whether Self-HPV may be an accurate method for the follow-up of women with a history of HPV infection.
- Trial name
- NCT02811367
- Testing
- HPV test
- Where
- Madagascar
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Respiratory Failure, Mechanical Ventilation Complication
Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI)
The purpose of this study is to document the prevalence and type of asynchronies incidence during non-invasive mechanical ventilation in pediatric patients breathing under pressure support.
- Trial name
- NavPed-NI (NCT01238757)
- Testing
- Non-invasive Ventilation under Pressure Support, Non-Invasive ventilation under NAVA
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University Hospital, Geneva
Human Papillomavirus Infection
A Comparison of Cotton and Flocked Swabs for Vaginal Self Collection
The purpose of this study is to compare the performance of cotton and flocked swabs for vaginal self-sampling.
- Trial name
- NCT02785289
- Testing
- Vaginal swab
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Chronic Pain, Acute Pain
Study to Test the Value of a Pain Modulation Test in Predicting Persistent Postoperative Pain After Breast Cancer Surgery
The purpose of this study is to test the hypothesis that a preoperative test of pain modulation predicts persistent pain 4 months after breast cancer surgery.
- Trial name
- PREDO (NCT01767168)
- Testing
- comprehensive preoperative testing for risk factors of persistent postoperative pain
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Geneva
Severe Sepsis, Emergency
Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery
This study wants to compared the safety and efficacy of GDTs using standard pressure-related parameters vs. dynamic hemodynamic indices associated with fluid compartment monitoring, in septic patients requiring emergency surgery.
- Conditions
- Severe Sepsis, Emergency, Surgery
- Trial name
- NCT01654003
- Testing
- CONTROL, OPTIMIZED
- Where
- 2 sites in Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Geneva
Hypovolemic Shock, Trauma
Impact of Early Goal-directed Fluid Therapy in Hypovolemic Patients Undergoing Emergency Surgery
This study compares the safety and efficacy of GDTs using standard pressure-related parameters vs. dynamic hemodynamic indices associated with fluid compartment monitoring, in trauma patients requiring emergency surgery.
- Conditions
- Hypovolemic Shock, Trauma, Emergency, Surgery
- Trial name
- NCT01653977
- Testing
- CONTROL, OPTIMIZED
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Geneva
Electromagnetic Interference
Evaluation of Interference Between Cell Phones and Implantable Cardioverter Defibrillators
Evaluation of electromagnetic interference between modern cell phones and contemporary implantable cardioverter defibrillators (ICDs)
- Trial name
- NCT02330900
- Testing
- Study group
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Geneva
CNS Tumor, Adult
Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma
RATIONALE : IMA 950 is multi tumour-associated peptides (TUMAPs) vaccine, these peptides have been identified on primary glioblastoma multiforme (GBM) cells.
- Trial name
- NCT01920191
- Testing
- IMA 950, Poly ICLC, Immunomonitoring
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- University Hospital, Geneva
Parathyroid Function Low Adverse Event
Assessing Parathyroid Glands Vascularisation by ICG Fluoroscopy
Evaluate parathyroid gland perfusion during total thyroidectomy or thyroid totalisation surgery. Create an objective basis for the decision whether or not to transplant the parathyroid glands.
- Trial name
- NCT02249780
- Testing
- Postoperative parathyroid function test, No postoperative parathyroid dosage and supplementation, ICG parathyroid angiography
- Where
- Switzerland
- Volunteers
- 146 people
- Sponsor
- University Hospital, Geneva
Pregnancy
The Influence of Hormonal Changes During Pregnancy on Corneal Biomechanics in Humans
The intraocular pressure in the human bulbus requires that the "wall" of the eye shows a certain (bio)mechanical strength. The human cornea represents the anterior portion of this wall.
- Trial name
- NCT01629264
- Testing
- Ocular Response Analyzer, Scheimpflug measurement, Blood sample
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Emergency Medical Services, Triage
Reliability of the Swiss Emergency Triage Scale (SETS®) Used by Emergency Medical Service (EMS) Providers
The Swiss Emergency Triage Scale (SETS) in used for triage in emergency departments in Switzerland, France and Belgium. No validated triage scale is actually used by Emergency Medical Service (EMS) providers.
- Trial name
- NCT02559531
- Testing
- Mobile triage system
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Alcoholic Intoxication
Emergency Department (ED) Triage of Alcohol Abuse
Retrospective study of adult patients (> 16 y) admitted to Geneva University Hospitals with alcohol abuse. Triage criteria will be reviewed. Patients characteristics and patient flow in the ED will be described.
- Trial name
- NCT02449772
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 775 people
- Sponsor
- University Hospital, Geneva