Clinical trials: sponsored by University Hospital, Geneva
Obstructive Sleep Apnea
To Study the Impact of CPAP on Gait Parameters in OSA Patients
To study the impact of CPAP therapy on gait in patients with obstructive sleep apnea syndrome.
- Trial name
- OSA_Gait (NCT02061046)
- Testing
- CPAP therapy
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Circadian Rhythm, Diabetes
Study of Circadian Clock Properties in Healthy Subjects, Obese and Type 2 Diabetic Patients.
The investigators aimed to characterize human circadian clockwork in healthy individuals in comparison to obese and type 2 diabetic subjects, employing the noninvasive experimental approach allowing the study of circadian profile…
- Conditions
- Circadian Rhythm, Diabetes, Obesity
- Trial name
- NCT02384148
- Testing
- Circadian rhythm measurement, Skin biopsy
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Critical Illness, Body Weights
Energy Expenditure in ICU Patients Using Predictive Formulas and Various Body Weights Versus Indirect Calorimetry
Indirect calorimetry is the gold standard to measure energy expenditure. In fact it is not always available and inconstantly feasible. Various equations for predicting energy expenditure based on body weights have been created.
- Trial name
- NCT02552446
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- University Hospital, Geneva
Intubation Conditions
Rapid Sequence Intubation With Magnesium-rocuronium Compared With Succinylcholine - A Randomised Clinical Study
Magnesium accelerates the reaction of rocuronium, a neuromuscular blocker used for muscle relaxation to ease the intubation during anaesthesia. Succinylcholine is a very fast reacting neuromuscular blocker.
- Trial name
- MagInRoc (NCT01571908)
- Testing
- Magnesium perfusion, Rocuronium, Succinylcholine
- Where
- 2 sites in Switzerland
- Volunteers
- 280 people
- Sponsor
- University Hospital, Geneva
Aspiration of Gastric Contents, Gastric Emptying
The Effect of Intravenous Erythromycin on Gastric Emptying in Non-fasted Patients Before Emergency Total Anesthesia
In this study the investigators want to investigate the effect of a short intravenous infusion of Erythromycine on gastric emptying on patients considered "full stomac" and scheduled for Emergency operation.
- Trial name
- NCT00827216
- Testing
- Erythromycin
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- University Hospital, Geneva
Cervical Dysplasia
Endocervical Evaluation With the Curette Versus Cytobrush for the Diagnosis of Dysplasia of the Uterine Cervix
OBJECTIVE: to compare endocervical brushing with endocervical curettage with respect to diagnostic and patient discomfort. METHOD: women referred to colposcopy because of abnormal Papanicolaou tests will be randomized to…
- Trial name
- NCT01435590
- Testing
- Curette v/s endocervical brush
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Chronic Hepatitis C
Retreatment of Chronic Hepatitis C Non-responders With Pegylated Interferon Alpha Plus Ribavirin Plus Pioglitazone
The aim of this study is to investigate the efficacy and safety of an insulin-sensitizer (Actos) added to a standard Pegasys/Copegus combination therapy of chronic hepatitis C in patients who have previously failed a…
- Trial name
- NCT00433069
- Testing
- Pioglitazone, Interferon Alfa-2a, Ribavirin
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Depression
Drug Metabolism and Antidepressant
We propose here to explore systematically the association between drug-metabolizing enzymes activity assessed by a phenotypical approach and antidepressant plasma concentration, efficacy and tolerance in the clinical setting.
- Trial name
- METADEP (NCT02438072)
- Testing
- Omeprazole (10 mg, A02BC01)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Hyponatremia
Relationship Between Heat Wave and Hyponatremia
The objective of this study is to explore the relationship between moderate to severe hyponatremia and heat.
- Trial name
- NCT02012660
- Testing
- Seasonality
- Where
- Switzerland
- Volunteers
- 28,734 people
- Sponsor
- University Hospital, Geneva
Electromagnetic Interference
Evaluation of Interference Between Bioelectrical Impedance Analysis and Implantable Cardioverter Defibrillators
Evaluation of electromagnetic interference between Bioelectrical Impedance Analysis (BIA) and implantable cardioverter defibrillators (ICDs).
- Trial name
- NCT02349737
- Testing
- Exposure to BIA interference with the ICD
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University Hospital, Geneva
Obesity
Dance Therapy and Obesity
Title: The effect of dance-therapy on the functional capacity, body image and quality of life of patients with advanced obesity Project duration: 33 months (August 2010 to June 2013) Clinical context: Obesity has reached epidemic…
- Trial name
- NCT01451892
- Testing
- Dance Therapy, patient education
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Aphasia
Effect of Dopaminergic Medication on Recovery of Aphasia
The investigators have been offering computer assisted therapy of aphasia (CAT) as a complement to traditional treatments to aphasia patients of the "Service of Neurorehabilitation" for some years.
- Trial name
- NCT00941265
- Testing
- levodopa and benserazide
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Pneumonia, Ventilator-Associated
Can we Better Understand the Development of VAP and Eventually Predict and Prevent it?
Pathogens of ventilator-associated pneumonia (VAP) come from colonizers of the trachea. The hypothesis of the investigators is that during the first days of intubation, independently of the use of antibiotics, there is a change…
- Trial name
- NCT01875692
- Where
- Switzerland
- Volunteers
- 286 people
- Sponsor
- University Hospital, Geneva
Type 1 Diabetes Mellitus
Islet of Langerhans Graft Monitoring by Magnetic Resonance Imaging
The primary objective of this pilot study is to assess the feasibility and safety of ex vivo islet labelling prior to intraportal transplantation in patients with type 1 diabetes with the purpose of islet graft imaging.
- Trial name
- NCT00453817
- Testing
- ferucarbotran (iron-based MRI contrast agent), Islet transplantation, Magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position
Maternal Positioning and Occipitoposterior Fetal Position
The aim of the study is to evaluate the efficacy of a specific maternal position to correct fetal position in occipito-posterior during the labor.
- Conditions
- Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position, Dystocia, Fetal Position and Presentation Abnormalities
- Trial name
- NCT01291355
- Testing
- Specific maternal position during the labor
- Where
- 2 sites in Switzerland
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Glioblastoma, Gliosarcoma
Sorafenib in Newly Diagnosed High Grade Glioma
This is a phase I study to evaluate the safety and tolerability of Sorafenib in combination with Temodar and radiation therapy in patients with newly diagnosed high grade glioma (glioblastoma, gliosarcoma, anaplastic astrocytoma…
- Conditions
- Glioblastoma, Gliosarcoma, Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma
- Trial name
- NCT00884416
- Testing
- Sorafenib dose escalation
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University Hospital, Geneva
Fever Without Source
Impact of the Lab-score on Antibiotic Prescription Rate in Children With Fever Without Source
Detecting serious bacterial infections (SBI) in children presenting to the Pediatric Emergency Department (PED) with fever without source (FWS) is a frequent diagnostic challenge.
- Trial name
- NCT02179398
- Testing
- Allocation to the Lab-score group, Allocation to the control group
- Where
- Switzerland
- Volunteers
- 278 people
- Sponsor
- University Hospital, Geneva
Acquired Platelet Disorder
Ex-Vivo Reversion of Platelet Inhibition Induced by Prasugrel
The purpose of this ex-vivo study is to estimate the optimal platelet quantity necessary to reverse the antiplatelet effects of prasugrel.
- Trial name
- NCT01839968
- Testing
- Ex vivo addition of normal platelet rich plasma to prasugrel-treated platelet rich plasma
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University Hospital, Geneva
MRSA Infection
Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
MRSA infections often require systemic antibiotic therapy and represent an important healthcare burden. Currently available treatment options are either only available in parenteral form (vancomycin) or expensive (linezolid).
- Trial name
- NCT00711854
- Testing
- trimethoprim-sulfamethoxazole (TMP-SMX), Linezolid, Rifampicin
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Geneva
Agitation
Quality Improving Program on Agitation in the Surgical Intensive Care Unit
Agitation in the intensive care unit can have multiple consequences. The investigators hypothesize that agitation and its consequences can be reduced by the introduction of a reminder aiming at guiding the management of…
- Trial name
- NCT02199262
- Testing
- music intervention, reflexology, reminder
- Where
- Switzerland
- Volunteers
- 1,107 people
- Sponsor
- University Hospital, Geneva