Clinical trials: sponsored by University Hospital, Geneva
Healthy, Immunosuppressed
Epidemiology and Clinical Presentation of H1N1 Infection in Children in Geneva
This study aims to identify clinical symptoms and outcomes, as well as response to anti-viral treatment in children living in Geneva, with influenza A/ H1N1 infection during the current pandemic.
- Conditions
- Healthy, Immunosuppressed, Asthmatic, Neuromuscular Diseases
- Trial name
- NCT01022931
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Geneva
Cirrhosis, Ascitis
Utility of Renal Biomarkers in Cirrhosis
Evaluation of kidney function is critical in cirrhotic patients as there is a clear relationship between renal failure and prognosis.
- Trial name
- NCT01217983
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- University Hospital, Geneva
Pulmonary Embolism
Multi-Detector Spiral Computed Tomography Alone Versus Combined Strategy With Lower Limb Compression Ultrasonography in Outpatients Suspected of Pulmonary Embolism
The main hypothesis for this study is that the diagnostic approach of pulmonary embolism (PE) by evaluation of clinical probability, D-dimer test dosage and multi-detector helical computed tomography (hCT) is as safe as the…
- Trial name
- NCT00117169
- Testing
- multi-detector helical computed tomography
- Where
- Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Geneva
Neurologic Disorder
Comparison Between Respiratory Therapy With Cough Assist Technique and Usual Respiratory Therapy in Intensive Care Patients Suffering of Neurologic Disorder
The present study aims to compare the efficiency of respiratory therapy with cough assist and the efficiency of usual respiratory therapy in intensive care patients suffering of neurologic disorder and cough ineffectiveness.
- Trial name
- NCT01143103
- Testing
- Cough assist (Philips,respironics), Usual respiratory therapy
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Non Invasive Ventilation, Patient Ventilator Interaction
Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive…
- Trial name
- NCT01074866
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- 4 sites in Belgium, Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Postoperative Wound Infection
Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation
Surgical site infections (SSI) constitute a significant health-economic and clinical challenge. The investigators conducted a cluster-randomized, cross-over study to compare the efficacy of plain soap and water (PSW), used…
- Trial name
- NCT00987402
- Testing
- Plain soap and water (PSW), Alcohol-based hand rub (ABHR)
- Where
- Kenya
- Volunteers
- 3,317 people
- Sponsor
- University Hospital, Geneva
MRSA Infection
Two Strategies for Methicillin-resistant Staphylococcus Aureus (MRSA) Infection Prevention in Surgical Patients
The study is a two-arm controlled multi-centre trial of two strategies to reduce nosocomial MRSA transmission and infection among surgical patients. Enrolment and primary analyses will be performed at the hospital level.
- Trial name
- MOSAR-04 (NCT00685867)
- Testing
- Rapid molecular MRSA test, Hand hygiene promotion
- Where
- Switzerland
- Volunteers
- 126,750 people
- Sponsor
- University Hospital, Geneva
Stroke, Foramen Ovale, Patent
Prospective Clinical Follow-up After the Percutaneous Closure of a Patent Foramen Ovale
Following a cryptogenic stroke, many patients are nowadays treated with the percutaneous closure of a patent foramen ovale (PFO), assuming that the aetiology of the stroke is secondary to a paradoxical embolism.
- Trial name
- PFO-HUG (NCT01149447)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Geneva
Peripheral Artery Disease Without Critical Limb Ischemia
Non-Healing Ulcers Without Critical Limb Ischemia
Background: Lower limb arterial revascularization procedures, either percutaneously or surgically performed, are an established treatment modality of ischemic foot ulcers, especially in the setting of a critical limb ischemia.
- Trial name
- NEWLI (NCT01666093)
- Testing
- Angioplasty of the lower limbs vessels
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Pulmonary Embolism
Angiojet Rheolytic Thrombectomy in Case of Massive Pulmonary Embolism
This pilot study is mainly aimed to evaluate the feasibility and safety of the percutaneous Angiojet Rheolytic Thrombectomy (ART) in patients presenting a MPE.
- Trial name
- ART-MPE (NCT00780767)
- Testing
- ANGIOJET RHEOLYTIC THROMBECTOMY
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University Hospital, Geneva
Enterobacteriaceae Infections
Enterobacteriaceae Producing Extended-spectrum β-lactamases (ESBL) Decolonization Study
Multidrug-resistant Enterobacteriaceae producing extended-spectrum β-lactamases (hereafter called ESBLs) have emerged as an important cause of bloodstream infection in hospitalized patients and urinary tract infections in the…
- Trial name
- NCT00826670
- Testing
- Decolonization
- Where
- Switzerland
- Volunteers
- 58 people
- Sponsor
- University Hospital, Geneva
Colorectal Disorders
Fast-Track Colorectal Surgery in Senior Patients
Fast-track (FT) surgery is a multimodal, multidisciplinary-team approach to reduce perioperative surgical stress and injury after colorectal surgery, resulting in lower morbidity and enhanced recovery.
- Trial name
- FT-SS (NCT01646190)
- Testing
- Preoperative Carbohydrate load, individualized i.v fluids therapy, Fasting state after midnight
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Geneva
Neuromuscular Block
Efficacy of Sugammadex in Magnesium Pretreated Patients
Sugammadex is a new reversal agent for neuromuscular blockers (curare). It encapsulates the curare molecule and terminates immediately its action.
- Trial name
- MagSug (NCT01440933)
- Testing
- Magnesium Sulfate
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University Hospital, Geneva
Visceral Obesity, Colorectal Surgery
Visceral Obesity and Colorectal Surgery
While perirenal fat measurement is an easy reproducible surrogate of visceral fat, its value as independent parameter in predicting postoperative complications after colorectal resection remains poorly investigated.
- Conditions
- Visceral Obesity, Colorectal Surgery, Risk Factor
- Trial name
- NCT01620697
- Testing
- Colorectal surgery
- Where
- Switzerland
- Volunteers
- 224 people
- Sponsor
- University Hospital, Geneva
Severe Acute Pancreatitis
Effect of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis
The aim of the study is to evaluate the safety, the potential beneficial effect of epidural anesthesia on pancreatic perfusion and clinical outcome of patients with severe acute pancreatitis.
- Trial name
- NCT01607996
- Testing
- Epidural anesthesia, Patient controlled intravenous analgesia
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
HIV, Zidovudine Adverse Reaction
Safety of Reduced Dose Zidovudine (AZT) Compared With Standard Dose AZT in Antiretroviral-naïve HIV-infected Patients
The primary objective of the study is to compare the tolerance and safety between a low-dose Zidovudine (AZT) containing regimen (200 mg BID) and a standard dosage (300 mg BID) in HIV patients initiating a first line…
- Trial name
- AZTlowdose (NCT01540240)
- Testing
- Zidovudine
- Where
- Cameroon
- Volunteers
- 136 people
- Sponsor
- University Hospital, Geneva
Low Back Pain
The Effects of Unstable Shoes on Chronic Low Back Pain
Some physicians, physiotherapists and nurses use or even suggest unstable shoes in cases of low back pain. No studies on the real effects of these shoes on low back pain in health care professions have been carried out and…
- Trial name
- NCT01384071
- Testing
- Unstable shoes (MBT)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Geneva
Childhood Obesity
Exercise and Behavioral Therapy in Obese Children
The aim of this study is to compare the effects of exercise training and family-based behavioral treatment, either in individual or in group setting, in pre-pubertal children and their mother.
- Trial name
- NCT01506245
- Testing
- Family-based behavioral therapy
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Geneva
Obesity
Effects of Exercise on Arterial Function and Insulin Resistance Syndrome in Pre-pubertal Obese Children
The main purpose of this project is to investigate the effects of an exercise program on arterial function and cardiovascular diseases risk factors in obese and lean pre-pubertal children.
- Trial name
- NCT00801645
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Human Papillomavirus Infection
Randomized Comparison of Vaginal Self Sampling for Human Papillomavirus (HPV) Testing by Standard Versus Dry Vaginal Swabs
Human papillomavirus (HPV) assays are likely to be used in cervical cancer screening. Our objective is to simplify the method of collection of female genital tract specimens by determining if vaginal dry swabs are as accurate as…
- Trial name
- HPVDry (NCT01316120)
- Testing
- Compare different self-obtained specimen for HPV identification
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva