Clinical trials: sponsored by University Hospital, Geneva
Hernia, Ventral, Body Image
Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair
Background: Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Primary repair without mesh reinforcement is almost abandoned because of high recurrence rates (24 to 46%).
- Conditions
- Hernia, Ventral, Body Image, Respiratory Function Tests, Quality of Life
- Trial name
- GINCISHERNIA (NCT00625053)
- Testing
- Laparoscopic repair, Open midline incisional hernia repair
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
Inguinal Hernia, Laparoscopic Surgery
Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy
Background: Large acceptance of mesh reinforcement techniques in groin hernia repair lowered recurrence rates for all techniques. Recurrence rate alone is not the main quality criterion for hernia repair anymore.
- Conditions
- Inguinal Hernia, Laparoscopic Surgery, Pain, Sexual Dysfunction, Physiological
- Trial name
- GENINGHERNIA (NCT00625534)
- Testing
- Laparoscopic totally extraperitoneal inguinal hernia repair, Open tension free inguinal hernia mesh repair
- Where
- Switzerland
- Volunteers
- 260 people
- Sponsor
- University Hospital, Geneva
Tuberculosis
Results of an Interferon-Gamma Release Assay After Treatment for Tuberculosis
New blood tests have become available to detect either latent or active tuberculosis. These tests - which according to the CDC can replace the tuberculin skin test - measure the production of gamma-interferon (a cytokine) by…
- Trial name
- NCT00595907
- Where
- Switzerland
- Volunteers
- 89 people
- Sponsor
- University Hospital, Geneva
Tuberculosis, Latent Tuberculosis Infection
Use of a Gamma-IFN Assay in Contact Tracing for Tuberculosis in a Low-Incidence, High Immigration Area
After exposure to an active case of tuberculosis (TB), close contacts may be infected. They are then considered as having latent tuberculosis infection (LTBI).
- Trial name
- NCT00557765
- Where
- Switzerland
- Volunteers
- 295 people
- Sponsor
- University Hospital, Geneva
Urinary Incontinence
Burden of Urinary Incontinence in Home Care Patients in the State of Geneva
Urinary incontinence (UI) is a frequent problem in community-dwelling older adults and has a huge burden on health complications and healthcare costs.
- Trial name
- NCT00530036
- Volunteers
- 699 people
- Sponsor
- University Hospital, Geneva
Cardiovascular Diseases
Stair Instead of Elevator Use at Work: Cardiovascular Primary Preventive Effects on Hospital Employees.
This is an intervention study which evaluates the cardiovascular primary preventive effects of using stairs instead of elevators at the worksite during a 12-weeks period.
- Trial name
- NCT00520195
- Testing
- Physical activity
- Where
- Switzerland
- Volunteers
- 77 people
- Sponsor
- University Hospital, Geneva
Hyperparathyroidism
Interaction Between Anaesthetics and Methylene Blue
We hypothesized that pre-treatment with methylene blue could potentiate the effects of general anaesthetic agents in patients undergoing parathyroidectomy
- Trial name
- NCT00513032
- Testing
- methylene blue
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University Hospital, Geneva
Lung Injury, Acute, Thoracotomy
Prevention of Lung Edema After Thoracic Surgery
Background : Acute lung injury (ALI) occasionally occurs after pulmonary resection and carries a bad prognosis with a high mortality rate ranging from 20 to 100%. Objectives : 1.
- Conditions
- Lung Injury, Acute, Thoracotomy, Anesthesia, Intensive Care, Surgical
- Trial name
- NCT00498251
- Testing
- inhalation of salbutamol (5 mg), ipratropium
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Efficacy of Average Volume Assured Pressure Support With Bi-Level Pressure Support Nocturnal Ventilation
Patients with chronic hypercapnic respiratory failure can be successfully treated with home nocturnal non-invasive ventilation. Bi-level pressure support ventilators are at present the most frequently used ventilators for long…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00479284
- Testing
- Average volume assured pressure support (AVAPS)
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University Hospital, Geneva
Hepatocellular Carcinoma
Intravascular Ultrasound for Hepatocellular Carcinoma Staging
To diagnose hepatocellular carcinoma (HCC) and to determine the extent of the disease, a triphasic CT scan or a magnetic resonance imaging are required.
- Trial name
- NCT00474734
- Testing
- Intravascular ultrasound of the liver
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Hepatitis C
Ribavirin/Pegasys Treatment of Recurrent Hepatitis C After Liver Transplant
The aim of the study is to assess whether patients with recurrent hepatitis C after liver transplantation will benefit from a treatment with ribavirin/PEG-IFN-alpha combined treatment for 48 weeks.
- Trial name
- NCT00466219
- Testing
- Ribavirin, Pegylated interferon alpha2a
- Volunteers
- 25 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation
Usefulness of Markers to Predict Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation
Catheter ablation using radiofrequency is a new therapeutic tool to treat atrial fibrillation with a higher success rate than medical therapy (80% versus less than 50% respectively).
- Trial name
- NCT00315068
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Pancreatic Neoplasms, Cholangiocarcinoma
Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter
Introduction In patients with a biliary obstruction, tissue is acquired immediately before drainage during endoscopic retrograde cholangio-pancreatography (ERCP).
- Conditions
- Pancreatic Neoplasms, Cholangiocarcinoma, Pancreatitis
- Trial name
- NCT00160836
- Testing
- Tissue sampling ("G.I.U.M." catheter)
- Where
- 3 sites in Argentina
- Volunteers
- 68 people
- Sponsor
- University Hospital, Geneva
Critical Illness, Respiratory Failure
Sedation in the Intensive Care Unit
High-risk critically ill patients often require mechanical ventilation either to primarily support the respiratory function or when the ventilation is insufficient to maintain adequate gas exchanges as a result of other organ…
- Trial name
- NCT00221520
- Testing
- midazolam with 2 different levels of sedation scores
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- University Hospital, Geneva
HIV Infection, AIDS
Staccato: A Trial of CD4 Guided Treatment Interruption, Compared to Continuous Treatment, for HIV Infection
Treatment of HIV repairs the immune system, but continuous treatment is expensive and causes side effects. Would it not be better to treat intermittently, e.g.
- Trial name
- NCT00113126
- Testing
- Treatment interruption
- Where
- Switzerland
- Volunteers
- 526 people
- Sponsor
- University Hospital, Geneva
Colonoscopy
Impact of a Self-Administered Information Leaflet on Adequacy of Colonic Cleansing for in-Hospital Patients
The quality of colon cleansing has a major impact on efficiency and cost of colonoscopy. A hand-out was made to instruct and motivate patients to adequately clean the bowel before colonoscopy.
- Trial name
- NCT00160823
- Testing
- Self-administered leaflet
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- University Hospital, Geneva
Cancer, Venous Thromboembolism
Prophylaxis of Venous Thrombo-Embolism in Cancer Patients Under Palliative Care
To determine the efficacy and to measure the complications of prophylactic anticoagulation using low-molecular weight heparin in adult cancer patients under palliative care
- Trial name
- NCT00303407
- Testing
- nadroparin
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Wound Infection
Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.
The aim of this study is to determine whether vancomycin with cefazoline is superior to vancomycin with placebo in preventing gastrostomy-related wound infection in carriers of methicillin-resistant staphylococcus aureus (MRSA).
- Trial name
- NCT00150852
- Testing
- Vancomycin
- Where
- 3 sites in France, Switzerland
- Volunteers
- 96 people
- Sponsor
- University Hospital, Geneva