Clinical trials: sponsored by University Hospital, Lille
Malignant Brain Tumor
Rates DMBT1 ( Glycoprotein) in Sputum of CF Patients With Pseudomonas Aeruginosa
Rates of DMBT1 (Glycoprotein like) in Sputum of CF Patients with or without may be different according to their Pseudomonas Aeruginosa chronic colonization status.
- Trial name
- DMBT1 (NCT02880111)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Chronic Disease, Patient Education as Topic
Determinants of Patients' Uptake of Therapeutic Education Programme
Therapeutic Patient Education (TPE) refers to programs that help patients to manage life with a chronic disease in the best possible way.
- Conditions
- Chronic Disease, Patient Education as Topic, Patient Adherence, Empathy
- Trial name
- UTEP (NCT03255863)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 459 people
- Sponsor
- University Hospital, Lille
Sars-CoV2
Bacterial and Fungal Microbiota of Patients With Severe Viral Pneumonia With COVID-19
Observational pilot single-center study aiming to determine the microbiota of critically ill patients infected with SARS-CoV-2. COVID-19 patients will be compared to historical critically ill controls with no SARS-CoV-2 infection.
- Trial name
- MICROVID (NCT04359706)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Lille
Liver Diseases
Ischemic Preconditioning at a Distance in Liver Surgery
During hepatic transection, it exists a high risk of perioperative blood loss. The haemorrhage and its consequences (hypovolemia and blood transfusion) might impact the short and long term morbidity The vascular control by…
- Trial name
- HEPATOPROTECT (NCT04181502)
- Testing
- pneumatic tourniquet, No inflation
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Psoriatic Arthritis
Changes in Body Composition Under Ustekinumab in PsA
There is not much body composition and bone mineral density data available for patients with psoriatic arthritis (rheumatoid arthritis) compared to control subjects.
- Trial name
- STELARA-CC (NCT03823924)
- Testing
- Bone mineral density (BMD)
- Where
- France
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Multiple Sclerosis, Systemic Sclerosis
Analysis of the Distribution of Regulatory B Cells in Blood of Multiple Sclerosis Patients
New therapeutic approaches of MS are emerging, targeting different actors of the immune system. Some of them target a specific population of white blood cells: B lymphocytes composed of different subpopulations.
- Trial name
- B-MS (NCT02789670)
- Testing
- Blood sample collection
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Immunocompromised Host, Critical Care
ICU-acquired Colonization and Infection Related to MDR in Immunocompromised Patients
the number of immunocompromised patients hospitalized in the intensive care units (ICU) is increasing. They are at higher risk of colonization and/or infection with multi-resistant bacteria (MDR).
- Trial name
- CIMDREA (NCT04043793)
- Where
- 7 sites in France
- Volunteers
- 759 people
- Sponsor
- University Hospital, Lille
Sleep Apnea Syndromes, Epilepsies, Partial
Study of the Efficacy of the Treatment of Sleep Apnea Syndrome by CPAP in Pharmacoresistant Epilepsy
Study of the Efficacy of the Treatment of Sleep Apnea Syndrome by CPAP in Pharmacoresistant Epilepsy. The primary goal is to evaluate the efficacity after 3 months of obstructive sleep apnea syndrome treatment by CPAP on the…
- Trial name
- SASER (NCT03200769)
- Testing
- CPAP active
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Lille
Multiple Sclerosis
Analysis of Neurodegenerative Process Within Visual Ways In Multiple Sclerosis
This study will interest in the pathophysiology of silent retinal axonal loss in multiple sclerosis. Recent studies have suggested that silent retinal axonal loss (no past history of optic neuritis [ON]) may be due to…
- Trial name
- VWIMS (NCT03656055)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Lille
Paraplegia, Hemiplegia
Evaluation of a Power Assistance Device for Wheelchair-DUO
Power assisted wheelchairs have specific advantages compared to manual propelled or powered Wheelchair. Autonomad Mobility has developed a new device (DUO), the assistance being triggered by the motion of the wheelchair and not…
- Trial name
- EVALDUO (NCT03386799)
- Testing
- E-motion device
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Lille
Alcohol Dependence
Advanced Nurses vs. General Practitioners for the Management of Outpatient Alcohol Detox: a Safety and Cost Comparison
The SAMBA study aims to assess the safety and cost comparison of the management of outpatient alcohol detoxification, between an advanced nurse protocol on the one hand (experimental group), and a GP-based treatment on the other…
- Trial name
- SAMBA (NCT03056365)
- Testing
- Advanced Nurse (AN), General Practitioner (GP)
- Where
- 26 sites in France
- Volunteers
- 73 people
- Sponsor
- University Hospital, Lille
Mechanical Ventilation
Hyperoxemia and Ventilator-associated Pneumonia
The aim of this prospective cohort single-center observational study is to determine the impact of hyperoxemia on ventilator-associated pneumonia (VAP) occurrence.
- Trial name
- SOH-VAP (NCT03434821)
- Where
- France
- Volunteers
- 534 people
- Sponsor
- University Hospital, Lille
Ankle Dislocation, Chronic Ankle Instability
Chronic Ankle Instability Diagnostic Tests Determining Underlying Deficits
Chronic ankle instability is a common condition in the active adult population and characterized by the occurrence of repeated giving way and/or recurrent ankle sprains.
- Trial name
- CAIDiag (NCT03818438)
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alzheimer's Disease, Cardiovascular Risk Factors
Impact of Controlling Vascular Risk Factors on the Progression of Alzheimer's Disease
Three quarters of patients with Alzheimer's disease have at least one vascular risk factor (VRF). Vascular brain lesions are present in most Alzheimer's patients (especially older ones).
- Trial name
- COVARAD (NCT01423396)
- Testing
- optimal care of VRF, standard care
- Where
- 21 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Lille
Stroke
Disconnection and Unilateral Spatial Neglect
Retrospective cohort study of consecutive patients investigated in a neurorehabilitation ward after a first hemispheric stroke. Unilateral spatial Neglect (USN) and other cognitive impairments (including attention, executive…
- Trial name
- DISCONEGLECT (NCT05268159)
- Testing
- Cognitive assessment
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille
Cerebral Hemorrhage
REstart or STop Antithrombotic Randomised Trial in France
RESTART- fr is a randomised controlled trial for adults surviving spontaneous intracerebral haemorrhage who had taken an antithrombotic drug (i.e.
- Trial name
- RESTART-Fr (NCT02966119)
- Testing
- Clopidogrel or Aspirin and/or Dypyridamole
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
Hyperventilation Syndrome
Work Productivity in Hyperventilation Syndrome
Hyperventilation syndrome is associated with impaired quality of life. The aim of the study is to assess the relationship between work productivity, including absenteeism and presenteeism, and the severity of hyperventilation…
- Trial name
- WHY (NCT03292523)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Islet Transplantation
Nephrologic Prognosis 10 Years After Diabetes Cell Therapy
Islet transplantation for type 1 diabetes results are still improving, and actually Insulin-independence with normal HbA1c is obtained in 50% of patients after 5 years, 80% of c-peptide positive patients.
- Trial name
- PRONOCELDIAB (NCT02627690)
- Testing
- islet transplanted, non islet transplanted
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Lille
Infertility
Evaluation of Pain in the Course of in Vitro Fertilization
25 to 50% of endometriotic patients are infertile and use medically assisted procreation. In general, the assessment of pain in medically assisted procreation is very little studied.
- Trial name
- ENDALGOFIV (NCT04103320)
- Testing
- Using different survey to evaluate pain
- Where
- France
- Volunteers
- 318 people
- Sponsor
- University Hospital, Lille
ARDS, Human
LIght Sedation Pressure Support
Sedation may have many drawbacks in ICU patients: cardiovascular, neurologic, muscular. Light sedation and Pressure Support ventilation is feasible in ARDS patients.
- Trial name
- LIPS (NCT03783468)
- Testing
- decrease of sedation doses and switch of ventilator settings
- Sponsor
- University Hospital, Lille