Clinical trials: sponsored by University Hospital, Lille
SARS-CoV 2
Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19
Mortality from Covid-19 increases with age, reaching 14.8% from the age of 80. The severity of the infection is linked to the acute respiratory distress syndrome (ARDS) which requires intensive care.
- Trial name
- ZnD3-CoVici (NCT04351490)
- Testing
- Zinc gluconate, 25-OH cholecalciferol
- Sponsor
- University Hospital, Lille
Inflammatory Bowel Diseases, Anesthesia
HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia
The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease
- Trial name
- HYSTERIA (NCT03261414)
- Testing
- Hypnosis, usual care
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Lille
Lynch Syndrome
Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome
Lynch Syndrome increases Endometrial Cancer Occurrence in women due to failure in MisMatch Repair System. Lifetime Cumulative risk of developing endometrial Cancer is approximatively 40% in women with Lynch Syndrome.
- Trial name
- PrediLynch (NCT04452266)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Sars-CoV2, Osteoporosis
Psychological Impact of Quarantine in Osteoporosis Patient During COVID-19 Outbreak
In the context of quarantine with COVID-19, we wish to study the experience and psychological impact in adult patients living with osteoporosis.
- Trial name
- OsPsyCOVID (NCT04351633)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Sars-CoV2, Chronic Pain
Psychological Impact of Quarantine in Chronic Pain Patient During COVID-19 Outbreak
In the context of quarantine with COVID-19, we will study the experience and psychological impact of pain in adult patients living with chronic pain.
- Trial name
- DolPsyCOVID (NCT04353011)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 312 people
- Sponsor
- University Hospital, Lille
Sars-CoV2, Rheumatic Diseases
Psychological Impact of Quarantine in Rheumatoid Arthritis Patient During COVID-19 Outbreak
Clinical data about psychological impact of quarantine are well studied in transient event or more prolonged situation like jail incarceration.
- Conditions
- Sars-CoV2, Rheumatic Diseases, Rheumatoid Arthritis, Chronic Pain
- Trial name
- PRPsyCOVID (NCT04351399)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 318 people
- Sponsor
- University Hospital, Lille
Olfactory Disorders, Scleroderma
Assessment of the Prevalence of Olfactory Disorders in Systemic Scleroderma
Prospective monocentric study of patients with systemic sclerosis disease. The primary outcome is to define the prevalence of olfactory disorders (hyposmia and anosmia) in systemic sclerosis disease.
- Trial name
- SCLEROLF (NCT04178616)
- Testing
- olfactory testing with specific odorants (localisation and identification)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
COVID-19, ARDS
Respiratory and Hemodynamic Changes Induced in Mechanically Ventilated Patients for COVID-19
In the present context, it seems necessary to try to describe as precisely as possible the physiological alterations due to COVID-19.
- Conditions
- COVID-19, ARDS, Sars-CoV2
- Trial name
- PHYSIO-COVID (NCT04347928)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Lille
Ankle Sprains
Follow up of Patients After a Visit to Tourcoing Emergency Department for an Ankle Sprain
Ankle sprain is very common. In France, its daily incidence is estimated at 6000. It often causes pain, a temporary period of disability and can results in recurrence and chronic ankle instability.
- Trial name
- CHEVILLE (NCT04114552)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Lille
Anorexia Nervosa
Neural Correlates of Self Body-shape Recognition in Anorexia Nervosa Mental
Body Image distortion is a key diagnostic feature for Anorexia Nervosa. Patients suffering from Anorexia Nervosa tend to perceive themselves as fatter than they are.
- Trial name
- Explorexie (NCT03799497)
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cognitive Symptom, Evaluations, Diagnostic Self
French Language Validation of the 5-minutes Montreal Cognitive Assessment (MoCA)
The aim of the study is to validate a french version of the 5 minutes version of the Montreal Cognitive Assessment as compared to the french full version of this test.
- Trial name
- MoCATEL (NCT03232697)
- Testing
- Full version of the Montreal Cognitive Assessment, 5 minutes version of the Montreal Cognitive Assessment
- Where
- France
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Digestive System Neoplasms, Thoracic Neoplasms
Educational Intervention to Increase the Emotional Competence of Patients With Oesogastric and Bronchopulmonary Cancers
The aim of this study is to test whether a short educational intervention about emotional skills can improve survivor cancer patient emotional skills and quality of life.
- Trial name
- EmoVie_K (NCT03306693)
- Testing
- Emotional skills, Relaxation and talking group
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
Inflammatory Bowel Diseases, Primary Sclerosing Cholangitis
NKT Role in the Regulation of the Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) include Crohn's disease (CD) and ulcerative colitis (UC). These diseases are a public health problem because they concern many patients (1 case in 1000).
- Trial name
- NKT-CSP/MICI (NCT02884557)
- Testing
- collection of gut biopsies collection of blood samples
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Lille
Immune Disease
Effect of Anti-CD303 Antibodies in Autoimmune Diseases
The pathogenic role of type I interferons (IFNs) in the development of different autoimmune diseases has been extensively described in the literature.
- Trial name
- ANTI-CD303 (NCT03370627)
- Testing
- Monoclonal anti-cd303 antibody
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Pain, Postoperative
PECS I Block for Breast Subpectoral Implant Surgery
Breast augmentation surgery can cause important postoperative pain, especially when bilateral subpectoral implants are used. The investigators hypothesized that a technique of regional analgesia, the pectoral nerve block type I…
- Trial name
- NCT02849236
- Testing
- Ropivacaine (PECS bloc)
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Lille
Schizophrenia
Cognitive and Emotional Factors in Visual Exploration Among Patients With Schizophrenia
Background: Patients with schizophrenia are abnormally disturbed by information onsets, which may result in a disadvantage in filtering relevant information.
- Trial name
- SAILLANCE1 (NCT02874482)
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Hemorrhage Postpartum, Fertility Disorders
Fertility After Intrauterine Tamponing Balloon: Where Are we
Today, few data are available on the patient's fertility following intrauterine tamponade balloon (BTIU) used for postpartum hemorrhage (PPH) after vaginal delivery (AVB).
- Trial name
- FERTIBTIU (NCT04133402)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
Sore Throat, Intubation;Difficult
Assessment of Post-operative Sore Throat After Scheduled General Anesthesia
Precise description of the technique for intubation or laryngeal mask placement during general anesthesia Research on factors that can influence sore throat due to the placement of an endobuccal or endotracheal device during…
- Trial name
- POST (NCT04115865)
- Testing
- Endotracheal sonde or laryngeal mask
- Sponsor
- University Hospital, Lille
Stroke, Spasticity, Muscle
Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
- Conditions
- Stroke, Spasticity, Muscle, Muscle Fatigue, Gait, Hemiplegic
- Trial name
- COCON (NCT03342820)
- Testing
- Muscle fatigue
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Orotracheal Intubation
Comparison of Haemodynamic Effects During Orotracheal Intubation, by Direct or Indirect Laryngoscopy With Airtraq
News techniques of intubation by indirect laryngoscopy have arrived in operating rooms but they are still too restricted to situations (difficult intubation criteria ..). It wanted to focus on indirect laryngoscopy by Airtraq.
- Trial name
- HEMODAIRTRAQ (NCT03743831)
- Testing
- orotracheal intubation by direct laryngoscopy, orotracheal intubation by indirect laryngoscopy
- Where
- France
- Volunteers
- 218 people
- Sponsor
- University Hospital, Lille