Clinical trials: sponsored by University Hospital, Lille
Suicide, Attempted
Evaluation of a Regional Post-discharge Monitoring System for Suicide Attempters
VigilanS is an innovative healthcare program. Participants of this program are all patients leaving in the Nord-Pas de Calais region who survived a suicide attempt.
- Trial name
- EVAL-VIGILANS (NCT03134885)
- Where
- 28 sites in France
- Volunteers
- 12,989 people
- Sponsor
- University Hospital, Lille
Congenital Heart Disease
Neurodevelopmental Disorders in Children With Congenital Heart Disease
Children with congenital heart disease are at risk for neurodevelopmental disorders, these disorders impacting their quality of life and their integration into society.
- Trial name
- NeuroDis-CHD (NCT03360370)
- Testing
- Ages & Stages Questionnaires, Third Edition in French (ASQ-3™)
- Where
- France
- Volunteers
- 233 people
- Sponsor
- University Hospital, Lille
Valve Heart Disease, Coronary Artery Disease
Post-Operative Myocardial Incident & Atrial Fibrillation
To explore predictors of major cardio-vascular events after cardiac surgery and trans-catheter valve implantation with a specific interest in studying mechanisms linking pre-operative leukocyte, fat and myocardial phenotypes with…
- Trial name
- POMI-AF (NCT03376165)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Lille
Post-Traumatic Stress Disorder
Cognitive and Emotional Factors in Visual Exploration Among Patients With Post-Traumatic Stress Disorder (SAILLANCE2)
Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats.
- Trial name
- SAILLANCE2 (NCT03519789)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Lille
Type1diabetes
Exercise Training and Endothelial Function in Type 1 Diabetes
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological…
- Trial name
- EVaDia (NCT03528226)
- Testing
- Exercise Training Procedure, Normal life procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Lille
Hip Osteoarthritis, Knee Osteoarthritis
Hip and Knee Scores
Patient-reported outcome measures (PROMs) are currently used for evaluating orthopaedic procedures. Nevertheless, there is no consensus in the different studies, making them difficult to compare .
- Trial name
- HIP-KNEE (NCT04057651)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Lille
Alzheimer Disease
Nonverbal Communication in Aged People
Musical interventions improve the emotional state of patients with Alzheimer's disease (AD) while having a positive impact on the caregiver's well-being.
- Trial name
- MAMUS (NCT04146688)
- Testing
- Music Balance Board
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Lille
Eosinophilic Asthma, Chronic Sinusitis
Eosinophils Endotypes in Chronic Airway Inflammatory Diseases
Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) are frequently described as unified airway inflammatory diseases. Both heavily impacts quality of life with substantial productivity loss.
- Conditions
- Eosinophilic Asthma, Chronic Sinusitis, Eosinophilic Rhinitis
- Trial name
- PLEIAD (NCT04187976)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Lille
Parkinson Disease
Dopaminergic restauratIon by intraVEntriculaire Administration
Prospective monocentric randomized controlled open-label proof-of-concept study in cross-over of two 1-month periods and a long-term follow-up period not to exceed September 30, 2023, with 2 groups: Intracerebroventricular…
- Trial name
- DIVE (NCT04332276)
- Testing
- A-dopamine, optimized oral treatment
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Lille
Gambling Disorder
Virtual Reality Exposure Therapy for Gambling Disorder
Gambling disorder (GD) is recognized as an addictive disorder in the DSM-5. Craving is a core phenomenon in addiction that can lead to relapse in problem gambling for pathological gamblers.
- Trial name
- VIRET-GAD (NCT04467502)
- Testing
- cognitive-behavioral therapy for gambling disorder, imaginal exposure therapy focus on gambling cues, virtual reality exposure therapy focus on gambling cues
- Where
- 10 sites in France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Lille
Asthma in Children
Consequences of COVID 19 Pandemic on Childhood Asthma
The SARS-CoV2 pandemic, which emerged in the first quarter of 2020, has led to an unprecedented health crisis in our modern healthcare systems and has resulted in strong national public health measures.
- Trial name
- VIRASTHCOVID (NCT04821908)
- Where
- France
- Volunteers
- 577 people
- Sponsor
- University Hospital, Lille
Post-Traumatic Stress Disorder, Violence-Related Symptom
A Case Management Algorithm for Women Victims of Violence
A considerable body of research has demonstrated that women who are victims of interpersonal violence are at substantially elevated risk for the development of post-traumatic stress disorder (PTSD).
- Trial name
- VIGITRAUMA (NCT04953273)
- Testing
- Vigitrauma
- Where
- 8 sites in France
- Volunteers
- 756 people
- Sponsor
- University Hospital, Lille
Renal Transplant Candidate for Right Kidney, Renal Transplant Candidate for Left Kidney
Evaluation of Regret in Kidney Transplantation
Decisional regret is a negative feeling, involving distress or remorse following a decision. This has been studied in several areas such as psychology, economy or marketing.
- Trial name
- DONOR (NCT05282381)
- Testing
- DRS : Decision Regret Scale
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Lille
type1diabetes, Renal Failure
Kidney Alone Versus Islet-After-Kidney in Type 1 Diabetic Kidney Transplant Recipient.
Islet transplantation is associated with a benefit on glycaemic control compared to optimized insulin therapy in recent clinical trials.
- Conditions
- type1diabetes, Renal Failure, End Stage Renal Disease
- Trial name
- KA-IAK (NCT05662267)
- Testing
- Pancreatic islet transplantation after kidney transplantation
- Where
- France
- Volunteers
- 327 people
- Sponsor
- University Hospital, Lille
SPINAL Fracture, Pain, Postoperative
Effectiveness of Erector Spinae Plane Block for Percutaneous Arthrodesis of Spinal Fractures
Spinal fracture surgery is a common surgery. Post-operative pain has been reduced by the advent of so-called minimally invasive techniques.
- Trial name
- SPINERECTOR (NCT06200298)
- Testing
- Erector spinae plane block with naropeine [3,75 mg/mL], ESPB with saline 0,9%
- Where
- France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Lille
Falls in the Elderly
Evaluating the Impact of "CHUT OTONOM®" Footwear on the Spatio-temporal Parameters of Walking and the Risk of Falls in Elderly People at High Risk of Falling.
Footwear is one of the extrinsic factors that can cause falls in older adults. Indeed, ill-fitting or worn shoes or slippers that do not support the foot properly, have slippery soles or high heels can contribute to falls.
- Trial name
- CHAUSS-THERA (NCT07366424)
- Testing
- "CHUT OTONOM®" shoes from Innothera Laboratories
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Lille
Necrotizing Fascitis, Cellulitis
Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions
The central venous-arterial carbon dioxide tension difference is used daily in intensive care to establish peripheral tissue hypoperfusion, mainly mediated by a low cardiac index.
- Conditions
- Necrotizing Fascitis, Cellulitis, Septic Shock
- Trial name
- SEPTICO2HBO (NCT07492030)
- Testing
- Echography
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Lille
Headache
LLM-Generated Lay Summaries for Brain MRI Reports
The goal of this clinical trial is to learn if a summary written by artificial intelligence (AI) helps adults understand brain MRI reports for headaches.
- Trial name
- CLEAR-HEAD (NCT07310394)
- Testing
- LLM-generated lay summary
- Where
- France
- Volunteers
- 2,727 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Falls in the Elderly
Follow-up of Elderly Subjects With Falls Recruited in the Geriatric Departments of Several French Hospitals
Falls are the leading cause of accidental death among the elderly, with nearly 8,000 deaths per year in France, including more than 950 deaths on average per year in the Northwest interregion between 2006 and 2013.
- Trial name
- PREMOB (NCT05281835)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille
Accidental Falls, Nursing Homes
Use of the KASPARD System for Fall Prevention in Nursing Homes
Falls are a frequent cause of admission to nursing homes [2]. It is also the most frequently reported adverse event in these institutions.
- Trial name
- KASPARD (NCT05457166)
- Testing
- KASPARD system for fall prevention in nursing homes
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille