Clinical trials: sponsored by University Hospital, Montpellier
Cryptorchidism
Role of the Environment and Endocrine Disruptors in Child Cryptorchidism
Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer.
- Trial name
- CRYPTENV (NCT04342026)
- Testing
- Measure of the exposure of parent of male with /without cryptorchidism to endocrine disruptors
- Where
- France
- Volunteers
- 1,452 people
- Sponsor
- University Hospital, Montpellier
Pigmentary; Dermatosis
Genomic Study of Cutis Tricolor
It's a study on Syndromic or Isolated Cutis Tricolor and had as main goal to identify the associated gene to the disease thanks to genetic analysis on minors patients and their parents reach by cutis Tricolor or not.
- Trial name
- Cutis Tricolor (NCT06073171)
- Testing
- Blood sample, Cutaneous biopsy, High troughput sequencing of human's exome
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Prospective multicenters randomized study to compare the efficiency and the socioeconomic impact of the endoscopic management (Overstitch technique) of weight regain after gastric bypass surgery to non invasive treatment
- Trial name
- APOLLO (NCT02048033)
- Testing
- Regular endoscopy + endogastric suturing, Regular endoscopy
- Where
- 7 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis
In rheumatoid arthritis (RA), the consensual 1st line conventional synthetic disease modifying antirheumatic drugs (csDMARD) of RA is methotrexate (MTX).
- Trial name
- SEQUENS-RA (NCT05428488)
- Testing
- Abatacept (W12-W48), TNF Inhibitor (W12-W48), TNF Inhibitor (W0-W12)
- Where
- 17 sites in France, Monaco
- Volunteers
- 220 people
- Sponsor
- University Hospital, Montpellier
Post-traumatic Stress Disorder (PTSD)
Early Intervention After Traumatic Exposure in Children and Adolescents
The aim of this interventional research is to evaluate the effectiveness of CFTSI in reducing post-traumatic symptoms measured using the CPC, child version, at the end of CFTSI treatment in children and adolescents aged between 7…
- Trial name
- ADAPT (NCT07207018)
- Testing
- CFTSI (Child and Family Traumatic Stress Intervention), non-specific psychological support therapy
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Lower Limb Chronic Oedema
Oedema Study : Chroedem
The chroedem study is aiming to assess tissue and biomolecular components of chronic lower limb oedema (CO). The investigators working hypothesis is that according to the aetiology of CO, the proportion of oedema \& composition…
- Trial name
- CHROEDEM (NCT02914808)
- Testing
- Patients will undergo a lower limb MRI and blood tests
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Adult ICU Patients
Electronic Distraction for ICU Patients
This is a feasibility study of electronic devices in order to reduce neuro-psychological disorders and suffering in intensive care unit (ICU) patients.
- Trial name
- CHOISIR (NCT04017299)
- Testing
- CHOISIR
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Intracranial Hypertension (IIH)
Intracranial Venous Stenting Evaluation in Patients With Idiopathic Intracranial Hypertension in the Early Phase
This study is aimed at patients suffering from recently discovered intracranial hypertension, caracterized by visual loss, chronic headache and/or tinnitus.
- Trial name
- DIVE IIN EARLY (NCT06919744)
- Testing
- Best medical care, Intervention (stenting)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer Female
Radioguided Occult Lesion Localisation by Indocyanine Green
Breast cancer is the most common cancer in women. It is the main cause of cancer deaths among women. The incidence of non-palpable tumors is estimated at 60%.
- Trial name
- ROLL-1 (NCT03313908)
- Testing
- detection of the tumor lesion
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Traumatic Brain Injury
Evaluation of Discriminating Power of Two Biomarkers in the Evaluation of Cerebral Lesions Due to Head Injuries in Infants and Children
Head injury is a frequent motive of consultation in paediatric emergency units and the first cause of mortality in infants of more than one year old in developped countries.
- Trial name
- TCOP100 (NCT02855034)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 167 people
- Sponsor
- University Hospital, Montpellier
Non Invasive Prenatal Diagnosis
NIPD on CFTC for Triplet Repeat Diseases
The purpose of this study is to develop and validate an analytical and clinical NIPD test for triplet repeat diseases by isolated circulating fetal trophoblastic cells (CFTC) analysis from maternal blood, searching for the…
- Trial name
- DIACCIMEX (NCT03087526)
- Testing
- Non invasive prenatal diagnosis
- Where
- 8 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Severe Obesity, GERD
Comparison of the Sleeve Gastrectomy Technique With a Nissen Fundoplication Added to the Conventional Sleeve Gastrectomy Technique in Morbidly Obese Patients
The purpose of this study is to evaluate the impact of the procedure (sleeve gastrectomy technique with a Nissen fundoplication (N-Sleeve) vs conventional sleeve gastrectomy technique
- Conditions
- Severe Obesity, GERD, Bariatric Surgery Candidate, Morbid Obesity
- Trial name
- N'SLEEVE (NCT04626232)
- Testing
- N-SLEEVE technique, SLEEVE
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Food Allergy
Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick Tests
Gibberellin-related proteins (GRPs) are proteins contained in both pollens and vegetables and are associated with an increased risk of severe food allergy reactions.
- Trial name
- GIBBERELLINES (NCT06183398)
- Testing
- Skin prick test
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Termination of Pregnancy, Feticide
Use of Ultiva ® Associated With Xylocaine ® in the Procedures of Feticide
The feticide is a legal and ethical obligation during a termination of pregnancy after 22 weeks' gestation. This method raise concerns about the fetal pain, maternal complications and the fetopathologic analysis.
- Trial name
- FOETIVA2 (NCT02597699)
- Testing
- Remifentanil + Lidocaïne, Sufentanil + Lidocaïne
- Where
- 2 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Surgery, Trauma to the Abdomen
Non Invasive Ventilation in Abdominal Postoperative Period
Acute respiratory failure may occur early in the postoperative course, requiring endotracheal intubation and mechanical ventilation in selected patients, thus increasing morbidity and mortality and prolonging intensive care unit…
- Conditions
- Surgery, Trauma to the Abdomen, Acute Respiratory Failure
- Trial name
- NIVAS (NCT01971892)
- Testing
- Non Invasive ventilation (facial mask and NIV ventilator), Standard oxygen therapy with facial mask
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Willis-Ekbom Disease, Restless Legs Syndrome
Analysis of Sympathetic Activity in Willis-Ekbom Disease
Willis-Ekbom disease (WED), also known as restless legs syndrome (RLS) is a common neurological sensorimotor disorder that typically impairs sleep and quality of life, likely consequent to a central dopaminergic dysfunction…
- Trial name
- MIBG-RLS (NCT02929732)
- Testing
- Sympathetic nervous activity measurement
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Suicidal Behaviour Disorder
Prevention of Suicidal Behavior Through the VIGILANS Protocol: the Restoration of Social Connection Hypothesis
The World Health Organization (WHO) estimates, with 800,000 annual deaths, that suicide is the second leading cause of death in people aged 10 to 44 and thus recognizes suicide prevention as a public health priority.
- Trial name
- RECONEX (NCT05227183)
- Testing
- The virtual version of the Social stress task : V-TSST
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Difficult Intubation
Risk Factors of Difficult Intubation and Related Complications in Adults in Intensive Care Units: FRIDA-Rea
Difficult intubation is challenging in intensive care units. There are limited data regarding risk factors of difficult intubation in ICU.
- Trial name
- FRIDA-Rea (NCT01532063)
- Testing
- INTUBATION IN INTENSIVE CARE UNIT
- Where
- France
- Volunteers
- 1,400 people
- Sponsor
- University Hospital, Montpellier
NSTEMI, NSTE-ACS (NSTEMI and UA)
Prognostic Impact of Guideline-recommended Timing for Invasive Strategy in NSTEMI
The objective of this multicentric observational study is to evaluate the prognostic influence of adherence or non-adherence to the recommended coronary angiography timeframe (within 24 hours) and the six-month prognosis of the…
- Conditions
- NSTEMI, NSTE-ACS (NSTEMI and UA), NSTEMI - Non-ST-Segment Elevation Myocardial Infarction
- Trial name
- NCT07204847
- Where
- France
- Volunteers
- 407 people
- Sponsor
- University Hospital, Montpellier
Cancer T1-N0 or T2-N0 of the Oral Cavity
Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O)
This is a single-center pilot study of open-label, non-randomized interventional research based on the outpatient management of 30 patients with T1-N0 or T2-N0 cancer in the oral cavity or oropharynx.
- Trial name
- SACO (NCT03545256)
- Testing
- outpatient surgery for T1-N0 or T2-N0 cancers of the oral cavity or oropharynx with lymph node search
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.