Clinical trials: sponsored by University Hospital, Montpellier
Current Major Depressive Disorder
Evolution of Dark Ideas When Introducing or Switching an Antidepressant
Depression is a frequent disease and a serious public health problem, of which suicide is the most severe complication. Its treatment is based on the introduction of antidepressant which not only proposes a significant delay in…
- Trial name
- DEPASSE (NCT03327974)
- Testing
- DEPASSE Apllication
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Montpellier
Bulimia, Binge Eating
Analysis of the Glycemic Profile of People Suffering From Compulsive Eating Disorders Aiming to Offer an Innovative Nutritional Approach (GLUCOPULSE)
Eating Disorders (ED) are a major public health problem. Current care remains only partially effective and the pathophysiology of the disorders remains to be deepened.
- Conditions
- Bulimia, Binge Eating, Blood Glucose, Low, Crisis State
- Trial name
- GLUCOPULSE (NCT04211818)
- Testing
- Eating Behavior, Blood glucose records
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Acute STEMI, Severe Left Ventricular Systolic Dysfunction (Disorder)
Use of Cardiac MRI in Early Stages of STEMI to Predict Left Ventricular Function Recovery and ICD Implantation
Patients presenting with STEMI and late revascularization can suffer from severe left ventricular dysfunction. Midterm and longterm mortality can be determined by the risk of fatal ventricular arrythmias.
- Trial name
- STEMI-MR (NCT03743935)
- Testing
- Gadolinium-enhanced cardiac MRI
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Vestibular Syndrome, Optokinetic Stimulation
Virtual Reality Compared to Other Forms of Optokinetic Stimulation in the Rehabilitation of Vestibular Syndromes.
Context and justification: Vertigo leads to medical consultation, interruption of daily activities or work stoppage in 80% of cases. Optokinetic stimulation is used in awareness and adaptation exercises.
- Trial name
- EquiRV (NCT03838562)
- Testing
- Vestibular rehabilitation with virtual reality, Standard optokinetic stimulator or dynamic visual surround
- Where
- France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Development of Specific Diagnostic Tools for Cardiac Insufficiency With Preserved Ejection Fraction
The MeDIAGSTOLE project aims to develop diagnostic tools for heart failure with preserved ejection fraction (IC / FEp), a pathology that is difficult to diagnose and to manage clinically in the absence of targeted treatment .
- Trial name
- MeDIAGSTOLE (NCT04699890)
- Testing
- Blood sampling, questionnaires and specific exams
- Where
- France
- Volunteers
- 91 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder, Third Wave Cognitive Behavioral Therapy
Self-Identification Program
Conduct a pilot, single-center, randomized controlled 2-arm study aimed to evaluate the impact of an in-depth 3rd wave CBT program targeting correct self-identification (3rd level of 3rd wave CBT), compared to a control group…
- Trial name
- SIP (NCT06183359)
- Testing
- SIP
- Where
- France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Montpellier
Chronic Disease
Analysis of the Efficiency of a Chronic Disease Self-Management Programme in a Vulnerable Population in Five European Countries
According to the World Health Organization (WHO), it is estimated that around 35% of women and 29% of men are affected by chronic conditions and this percentage is clearly influenced by specific risk factors, such as lifestyle…
- Trial name
- EFFICHRONIC (NCT03840447)
- Testing
- Chronic Disease Self-Management programme
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis, Swelling Joint
Characterization of Regulatory T Lymphocytes in the Synovial Fluid of Patients Affected by Rheumatoid Arthritis.
In rheumatoid arthritis (RA) the clinical response to anti-TNFα is related to an increase in the number or in the function of Treg lymphocytes in the peripheral blood of patients.
- Conditions
- Rheumatoid Arthritis, Swelling Joint, Joint Fluid, Characterization of Regulatory T Lymphocytes
- Trial name
- CATERLIS (NCT03293667)
- Testing
- Exploratory synovial fluid analysis
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier
Hospitalization, All Conditions
New Approaches for Evaluating the Interchangeability of Reference Materials and Quality Controls (COMET-MPL)
Medical biology tests are essential to clinical decision-making. The European Regulation on in vitro diagnostic medical devices (EU/2017/746) requires metrological traceability of the values assigned to calibrators and quality…
- Trial name
- COMET-MPL (NCT07173114)
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Severe and Symptomatic Aortic Stenosis, Stable Coronary Disease
Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study
Evaluation of a strategy of selected revascularization guided on myocardial ischemia detection after the TAVI procedure by using single photon emission computed tomography (SPECT) myocardial perfusion imaging.
- Trial name
- REVASC-TAVI (NCT02797158)
- Testing
- TAVI procedure
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Montpellier
Depression - Major Depressive Disorder, Depression Disorder
Link Between Reduction of Suicide Ideation by Esketamine in Add-On and Initial Levels of Psychological Pain and Anhedonia
This study is looking at how intranasal esketamine (a nasal spray) can help reduce suicidal thoughts in patients with severe depression who are experiencing suicidal thoughts.
- Conditions
- Depression - Major Depressive Disorder, Depression Disorder, Suicide
- Trial name
- IODA (NCT07199179)
- Where
- France
- Volunteers
- 456 people
- Sponsor
- University Hospital, Montpellier
Brachial Obstetrical Palsy
Anatomopathology of the Subscapularis and Infraspinatus Muscles in Children With Brachial Plexus Obstetric Paralysis
POPB is a consequence of the stretching of the nerve roots (C5, C6 + / C7, C8 or T1) of the brachial plexus at birth. One third of patients will have sequelae.
- Trial name
- POPB (NCT03771144)
- Testing
- arthrolysis
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Montpellier
Borderline Personality Disorder
SHame prOpensity in bOrderline Personality Disorder
Borderline Personality Disorder (BPD) is a common psychiatric disorder occurring in 2 to 6% of the population. 70% of patients with BPD do at least one Suicide Attempt (SA) in their lives.
- Trial name
- SHOO (NCT03994510)
- Testing
- Clinical and biological assessments - a 5 Years follow-up
- Where
- France
- Volunteers
- 688 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia
Cost-utility Study of a Group of Compensatory Cognitive Remediation in Schizophrenia
Significant cognitive impairment (executive functions, memory, attention) is common in schizophrenia affecting up to 80% of patients.
- Trial name
- Grecco (NCT02879604)
- Testing
- Compensatory cognitive training, Usual
- Where
- 9 sites in France
- Volunteers
- 218 people
- Sponsor
- University Hospital, Montpellier
Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Effectiveness of Autobiographical Rewriting Workshops on the Socio-Professional Functioning of Patients With Borderline Personality Disorder Undergoing Third-Wave Cognitive and Behavioral Therapy: A Randomized Controlled Trial
This study evaluates the effectiveness of autobiographical rewriting workshops combined with third-wave Cognitive Behavioral Therapy (CBT) in improving social and professional functioning in individuals with Borderline…
- Trial name
- ICS (NCT07199166)
- Testing
- Autobiographical Rewriting Workshops, Non-specific writing workshops
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Obesity
Mobile Tele-rehabilitation Solution for Obese Patients.
Published data indicate that rehabilitation in obese patients can result in a loss of body fat and weight that is correlated to improved physical and psychological condition and reduced morbidity and mortality.
- Trial name
- NCT03396666
- Testing
- Telemouv
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Acute Kidney Injury, Renal Replacement Therapy
Effects of Variation of Sodium Dialysate in ICU
Intermittent hemodialysis/diafiltration is a current renal replacement therapy (RRT) institued for ICU patients with AKI. For a better clinical tolerance, iinternational guidelines advise to use cold dialysate, increase duration…
- Trial name
- NADIRA (NCT03329313)
- Testing
- Lowering sodium concentration dialysate, Highing sodium concentration dialysate
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia, Schizoaffective Disorder
Video as a Tool to Improve Insight in Schizophrenia
The deficit of awareness of pathology (or insight) is a common symptom in patients with schizophrenia and has a negative impact on the prognosis of the disease.
- Trial name
- VideoInsight (NCT02664129)
- Testing
- Video self-observation, Non Self video observation
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Efficacy of PRADO Heart Failure in Occitania
Patients with heart failure (IC), after hospitalization, have a marked fragility: in France, in the first year, 29% die and 45% are readmitted to IC.
- Trial name
- PRADO-IC (NCT03396081)
- Testing
- PRADO-IC, No intervervention Usual Care
- Where
- France
- Volunteers
- 404 people
- Sponsor
- University Hospital, Montpellier
Asthma
Mepolizumab Pharmacokinetics Among Patients With Severe Asthma
Asthma is a chronic disease characterized by inflammation and obstruction of the airways. Identification of the mechanisms of action of corticosteroids has made it possible to define the type 2 inflammation present in nearly 80%…
- Trial name
- CESAM (NCT05495932)
- Testing
- blood sample
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
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