Clinical trials: sponsored by University Hospital, Montpellier
Cochlear Implant
Establish a Concordance Between the Mismatch Negativity Amplitude and a Score of Logatoms Discrimination
A cochlear implant is a device for the rehabilitation of severe to profound hearing loss. Despite the standardization of surgical procedures and rehabilitation, speech discrimination performance varied significantly in cochlear…
- Trial name
- EVODA-ICMN (NCT03025386)
- Testing
- logatoms test, Electroencephalography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Stenoses, Aortic
Sedation or General Anesthesia During TAVR
Transcatheter aortic valve replacement TAVR is become the reference method for patients with severe aortic stenosis who are contraindicated or at risk for surgical aortic replacement.
- Trial name
- ANESTAVI (NCT04347603)
- Testing
- TAVR
- Where
- 2 sites in France
- Volunteers
- 218 people
- Sponsor
- University Hospital, Montpellier
Stroke
Large Stroke Therapy Evaluation
Stroke represents the fourth leading cause of death in industrialized nations, after heart disease, cancer, and chronic lower respiratory disease.
- Trial name
- LASTE (NCT03811769)
- Testing
- Best Medical Therapy, Mechanical Thrombectomy
- Where
- France
- Volunteers
- 335 people
- Sponsor
- University Hospital, Montpellier
Low Grade Glioma of Brain
Measure of the Potential Evoked by Electric Stimulation
This study is about an experimental biomedical monocentric search concerning twelves patients presenting a infiltrative glioma of low rank OMS type II and realizing a surgery awakened on the site of the CHU of Montpellier.
- Trial name
- PE&CE (NCT02509442)
- Testing
- Diffusion of direct electric stimulation
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Congenital Heart Disease in Children, Neurodevelopmental Disorders
Feasibility and Efficiency of Screening for Neurodevelopmental Disorders by an Advanced Practice Nurse in Children With Congenital Heart Disease
Feasibility and efficiency of Screening for Neurodevelopmental Disorders by an Advanced Practice Nurse in Children aged 1 to 5 with Congenital Heart Disease
- Trial name
- NEURODEV-IPA (NCT06431269)
- Testing
- Screening for neurodevelopmental disorders by an advanced practice nurse
- Where
- 3 sites in France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Montpellier
Hypospadias
Hypospadias and Exome: Identification of New Genes for Familial Hypospadias
Hypospadias is the second most common malformation of the male genitalia and consists in a congenital hypoplasia of its ventral face.
- Trial name
- NCT02495090
- Testing
- Exome sequencing
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Cystic Fibrosis, CFTR Gene Mutation
Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies
Cystic Fibrosis, an inherited autosomal recessive disease, arises from mutations in the CFTR gene. For intronic mutations affecting splicing events, oligonucleotides therapy has the potential to restore the production of the full…
- Trial name
- ONB-CFTR (NCT05100823)
- Testing
- Nasal cells sampling, Rectal biopsy sampling
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Montpellier
Multiple Sclerosis
Montpellier PROspective Cohort in Relapsing Remitting Multiple Sclerosis Using Imaging and Serologic
Several prospective monocentric cohorts of between 250 and 1000 patients have been set up in order to characterize more precisely the evolution of the disease.
- Trial name
- PROMISE (NCT05962177)
- Testing
- Magnetic Resonance Imaging, Blood withdrawal, Neuropsychological tests
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Diabetes Type 1, Diabetes Type 2 on Insulin
Performance and Safety Evaluation of the EkiYou V2 Application in Patients With Diabetes Using Multiple Daily Insulin Injections (EkiYou-Study1)
EkiYou-Study-1 is an interventional before/after clinical investigation according to EU 2017/745. It is conducted in 21 adults with diabetes and treated by multiple daily insulin injections.
- Conditions
- Diabetes Type 1, Diabetes Type 2 on Insulin, Pancreatogenous Diabetes
- Trial name
- NCT06529705
- Testing
- EkiYou V2
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
Suicide, Suicide Attempt
Efficacy of a Smartphone Suicide Prevention App
It is an interventional research, single-blind, randomized, controlled, multicenter, which involves only minimal risks and constraints.
- Trial name
- PreventS (NCT07160465)
- Testing
- emma application
- Where
- France
- Volunteers
- 632 people
- Sponsor
- University Hospital, Montpellier
Keratoconus
Risk Factors and Progression of Keratoconus
Primary objective : Description of keratoconus at baseline and during progression in 200 participants followed by the ophthalmology departments of CHU Montpellier, CHU Bordeaux and CHU Toulouse during a 2-year period.
- Trial name
- FRPK (NCT05676580)
- Testing
- cross-linking surgery or intra corneal ring, abstention
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Acute Kidney Injury, Urinary Tract Obstruction
Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department
Acute kidney injury (AKI) is a common diagnosis in the emergency department (ED), and urinary tract obstruction is a contributing cause that requires rapid diagnosis and therapeutic management.
- Trial name
- NCT06040736
- Where
- France
- Volunteers
- 155 people
- Sponsor
- University Hospital, Montpellier
Students, Middle Schools
Evaluation of the Effect of the BOAT® Structured Prevention Program on Violence in Middle Schools
Violence has major consequences for the health and development of children and teenagers, even though it is commonplace, particularly in secondary schools.
- Conditions
- Students, Middle Schools, Prevention, Violence
- Trial name
- TheBOATeffect (NCT06471413)
- Testing
- The Prevention Toolbox : BOAT®
- Where
- France
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Auditory Hallucinations, Schizophrenia Spectrum
Cost-utility Study of Cognitive-behavioral Management of Auditory Hallucinations in Schizophrenic Disorder
The aim of the study is to assess the effectiveness and costs of a cognitive-behavioral treatment (CBT) for auditory hallucinations (psychotherapy) as an adjunct to usual care, comparing it to the effectiveness and costs of usual…
- Trial name
- VOICES (NCT07134816)
- Testing
- Cognitive and behavioral therapy for auditory hallucinations, Usual treatment
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier
Stenoses, Aortic Valve, Aortic Insufficiency
Perceval Aortic Bioprostheses : Durability Study.
Aortic valve replacement is one of the most commonly performed procedures in adult cardiac surgery in France. Patients over the age of 65 most often receive a bioprosthetic aortic valve during an isolated aortic valve replacement…
- Conditions
- Stenoses, Aortic Valve, Aortic Insufficiency, Aortic Diseases
- Trial name
- NCT07116265
- Volunteers
- 192 people
- Sponsor
- University Hospital, Montpellier
Long QT Syndrome, Congenital Long Qt Syndrome
Cardiac Rehabilitation of Children and Adolescent With Long QT Syndrome
Children and adolescents with inherited cardiac arrhythmia su ch Long QT Syndrome (LQTS) have lower physical and quality of life than their healthy peers.
- Conditions
- Long QT Syndrome, Congenital Long Qt Syndrome, Inherited Cardiac Conduction Disorder, Pediatric ALL
- Trial name
- RYTHMO'FIT (NCT05964322)
- Where
- 2 sites in France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Cleft Lip and Cleft Palate
Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate
Secondary rhino-septoplasty in unilateral cleft lip and palate is the treatment of choice for the correction of aesthetic deformities and the functional impact on ventilation nasal. It remains a difficult treatment.
- Trial name
- RHINOFENTE (NCT07048418)
- Testing
- Mailing and completing CLEFT-Q and NOSE questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Lower Limb Ligament Injury
Relationship Between Proprioceptive Flexibility and the Occurrence of Lower Limb Ligament Injury in Pivot-contact Sports
Among young athletes involved in pivot and pivot-contact sports (soccer, handball, rugby, etc.), lateral ankle sprains and lesions of the anterior cruciate ligament (ACL) are the most frequent ligament injuries.
- Trial name
- FlexiPro (NCT07028723)
- Testing
- proprioceptive profile measurement
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hematoma, Subdural, Chronic, Brain Diseases
The Onyx™ Trial For The Embolization Of The Middle Meningeal Artery For Chronic Subdural Hematoma
Middle meningeal artery (MMA) embolization via a minimally invasive endovascular approach might increase the likelihood of resolution and might prevent reaccumulation of Chronic Subdural Hematoma (CSDH).
- Conditions
- Hematoma, Subdural, Chronic, Brain Diseases, Central Nervous System Diseases, Wounds and Injuries
- Trial name
- OTEMACS (NCT04742920)
- Testing
- Middle Meningeal Artery Embolization, Standard Management
- Where
- 6 sites in France
- Volunteers
- 247 people
- Sponsor
- University Hospital, Montpellier
Non-Tuberculous Mycobacterial Pneumonia
Cellular Markers in Treated or Untreated Non-tuberculous Mycobacterial Respiratory Infection in Patients With Cystic Fibrosis
This study evaluates a diagnostic serological test for Non-Tuberculous Mycobacteria (NTM) infection in cystic fibrosis patients by measuring T cell response.
- Trial name
- MUCEM (NCT06602869)
- Testing
- Scheduled visit (V1)
- Where
- France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Montpellier
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