Clinical trials: sponsored by University Hospital, Montpellier
Depression - Major Depressive Disorder, Suicide
Sustained Ketamine Effectiveness for Suicidal Ideation
As part of the usual clinical activity of the Emergency and Post-Emergency Psychiatric Department, IV ketamine is used to treat suicidal crises in depressed patients hospitalized as an add-on to the treatment of depression.
- Trial name
- SKESI (NCT06806475)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Siblings
Screening for Neurodevelopmental Disorders in Siblings of Children With Autism Diagnosed in Tertiary Centers
In this study, a selective and multi-stages screening for neurodevelopmental disorders (NDD) in siblings of children with a confirmed ASD is done.
- Conditions
- Autism Spectrum Disorder, Siblings, Neurodevelopmental Disorders
- Trial name
- FRATSA (NCT05512637)
- Testing
- Step 1 - Screening ; Step 2 - Clinical interview
- Where
- France
- Volunteers
- 384 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder
Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk
Joiner's interpersonal theory of suicide postulates that the wish of death comes from feelings of perceived burdensomeness and thwarted belongingness.
- Trial name
- R2D2 (NCT04461327)
- Testing
- Painful stimulations of major depressive patients, Blood sample, Clinical assessment
- Where
- 2 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Montpellier
Radiology Interventional, Spinal Injections
RAdiology Consultation Effectiveness
Performing a consultation with the radiologist before a spinal invasive procedure serves to foster a trusting physician-patient relationship.
- Conditions
- Radiology Interventional, Spinal Injections, Back Pain
- Trial name
- RACE (NCT06762665)
- Testing
- Spinal injection, pre-operative consultation
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Montpellier
Spinal Cord Injury
Spinal Cord Injury: Impact on Sensory, Motor, Behavioral and Cognitive Functions
Spinal cord injury (SCI) causes a variety of sensory-motor deficits and neuropsychological consequences. Magnetic resonance imaging (MRI) reveals a reduction in the volume of the somato-sensory and motor cortices, as well as…
- Trial name
- SUPRASPINAL (NCT06887309)
- Testing
- MRI, Neuropsychological tests
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and…
- Conditions
- Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- Trial name
- MUSENGAGE (NCT06688968)
- Testing
- neuropsychologist interview, questionnaire
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Foot Surgery
The 5-in-2 Ankle Block for Outpatient Foot Surgery: the FIT Block Study
Hallux valgus surgery is known as a painful surgery. Qualitative pain management is the key to successful early recovery and rehabilitation.
- Trial name
- NCT06882109
- Testing
- Five-in-two ankle block
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Coagulopathy, Cardiopulmonary Bypass
Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy
This is a prospective study to evaluate the predictive value of the TEG 6s platelet mapping® (TEG 6s® PM) performed during cardiopulmonary bypass (CPB) in the prediction of biological coagulopathy (determined by TEG 6S global…
- Conditions
- Coagulopathy, Cardiopulmonary Bypass, Cardiac Surgery
- Trial name
- PREDIPOC (NCT06230640)
- Testing
- In vitro medical diagnostic device TEG6s® Platelet Mapping
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Leishmaniasis, Leptospirosis
Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases
Zoonoses and arboviroses refer to a group of diseases transmitted from animals to humans, either directly or indirectly (via mosquitoes, ticks or contact with contaminated environments).
- Conditions
- Leishmaniasis, Leptospirosis, Brucellosis, Q Fever
- Trial name
- SEZAM (NCT06859619)
- Testing
- Peripheral venous blood sample
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
HIV Infections
Development of a New Family of HIV Latency Regulators (LRAs) Targeting the Tat Viral Protein
Antiretroviral therapy (ART) prevents HIV from multiplying. However, if people living with HIV stop taking ART, the virus quickly reappears in their blood due to the random activation of hidden infected cells.
- Trial name
- TatLat (NCT06441123)
- Testing
- Blood Sampling
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier
Primary Disease Fascioscapulohumeral Dystrophy (FSHD)
Routine Health Care of Patients With FSHD
On the basis of published data and our results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, investigators conducted a pilot randomized double-blind placebo…
- Trial name
- FSHD (NCT02622438)
- Testing
- Followed with an initial assessment, 12 months and followed annually corresponding to the usual follow-up of the patient.
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Montpellier
Past Major Depressive Episode, Euthymic
Social Stress and Suicide
Only vulnerable patients, when facing environmental stressors, attempt or commit suicide. Previous research demonstrated that suicide attempters usually misunderstand the social context and show impairments in decision making.
- Trial name
- SUPHY (NCT04714671)
- Testing
- The virtual version of the Social stress task : V-TSST
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Cardiotoxicity, Childhood Cancer
Prediction of Delayed Toxic Cardiomyopathy in Children
Longitudinal analysis of myocardial function using "Speckle Tracking Echocardiography" STE analysis and prediction of delayed toxic induced cardiomyopathy in young patients who received anthracycline therapy in childhood.
- Trial name
- SpeckleAnthra2 (NCT05781672)
- Testing
- cardiac ultrasound with speckle tracking analysis
- Where
- France
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea, Coronary Disease
Patients with Coronary Artery Disease or At High Cardiovascular Risk: Measuring Compliance with Treatment for Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a sleep disorder characterised by partial or total obstruction of the oro-pharyngeal carrefour during sleep.
- Conditions
- Obstructive Sleep Apnea, Coronary Disease, Cardiovascular Diseases
- Trial name
- PACOAM (NCT06568159)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Heart Failure Diagnostic Performance of an Expirogram Analysis Algorithm Evaluating 4 Biomarkers
Telemonitoring is a key clinical issue in heart failure (HF). Bedside measurement systems using handheld devices provide "digital biomarkers" useful for remote monitoring.
- Trial name
- SenseIR-IC (NCT06014593)
- Testing
- expirogram
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Crohn Disease
Interest of the Dosage of Adalimumab Serum Levels in Crohn's Disease Patients for Prevention of Postoperative Recurrence
Study comparing 2 modalities of Crohn's disease patients postoperative follow-up treated with adalimumab (Humira® or biosimilar) : immunomonitoring of adalimumab serum levels versus standard follow-up, which is based on the…
- Trial name
- ADAPT (NCT04200547)
- Testing
- Immunomonitoring-based follow-up, Standard follow-up
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia, Psychotic Disorders
Investigation of Objective Cognitive Effort in Neuropsychological Evaluation of Psychotic Disorders
Psychotic disorders are characterised by a heterogeneity of symptoms, including cognitive disorders, which predict functional outcome. To date, the evaluation of cognitive functions essentially measures performance.
- Conditions
- Schizophrenia, Psychotic Disorders, Cognitive Impairment, Motivation
- Trial name
- INVESTIGECCO (NCT06782672)
- Testing
- Cardiovascular measurements, Experimental memory task, Questionnaire and semi-structured psychological interview
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Maxillary Hypoplasia
Skeletal and Dental Changes with Hyrax-type Rapid Maxillary Expander Anchored to Permanent Versus Deciduous Molars
The aim of the study is to compare the skeletal and dental maxillary expansion obtained with an Hyrax tooth-borne expander anchored either on the 2nd deciduous molars (V) or on the 1st permanent molars (6)
- Trial name
- DENTHYRAX (NCT05773573)
- Testing
- Experimental group, Control group
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Montpellier
Anorexia Nervosa
Study of the Difference Between Anorexia Nervosa with a History of Psychological Trauma and Classical Anorexia Nervosa on the Neurocognitive and Neurophysiological Factors
Recent studies suggest that patients with an history of trauma may represent a specific subtype of anorexia nervosa (AM) underlined by specific neurobiological and psychopathological mechanisms.
- Trial name
- ATAC (NCT04804358)
- Testing
- Exposition Test
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Montpellier
Functional Autonomy
Effects of a Serious Game With Elderly People
Assessment of the effect of a 12 weeks serious game based exercises program on physical performance in older adults living in nursing homes, in comparison with a control group that benefits from a classical exercise training…
- Trial name
- NCT03836911
- Testing
- serious game, classic program
- Where
- 15 sites in France
- Volunteers
- 136 people
- Sponsor
- University Hospital, Montpellier
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