Clinical trials: sponsored by University Hospital, Montpellier
Temporomandibular Joint Disorders
Validation of a Standardized Tool for Evaluation Function of Patients With TMD
Temporo-Mandibular Disorders (TMD) are the reason for consultation on more common in maxillofacial. However, there is no consensus on their care.
- Trial name
- DTM-SCORE (NCT03871608)
- Testing
- Examination of functional etiologies on DTM Disorders, Assessment of symptoms on DTM Disorders
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Benign Ovarian Cyst, Cystectomy
Benefit of Hemostatic Sealant in Preservation of Ovarian Reserve
Introduction : The most common technique used for ovarian cystectomy is the stripping technique. After stripping the cyst wall, the subsequent bleeding of the ovarian stromal wound is usually controlled by bipolar coagulation…
- Trial name
- FLOKIP (NCT05037552)
- Testing
- Bipolar coagulation, Coagulation by FLOSEAL haemostatic agent
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Frozen Embryo Transfer
Benefit of Amlodipine in HRT Cycle for Frozen Embryo Transfer in the Correction of Uterine Pulsatility Index
Embryo implantation depends on two main factors: embryo grading quality and endometrial receptivity.Numerous tools have been suggested to evaluate these two factors.
- Trial name
- AMLODIP (NCT04954196)
- Testing
- Amlodipine 5mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Antibody-mediated Rejection
Subclass of Donor-specific Antibody as a Risk Factor of Antibody Mediated Rejection in Renal Transplantation
Antibody-mediated rejection is now recognized as the first cause of long-term kidney transplant loss. This type of rejection is mediated by the presence of graft-specific antibodies, usually directed against HLA (Human Leukocyte…
- Trial name
- COR-HUM (NCT04026087)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Sars-CoV2
REassessement After Hospitalization for Sars-COV-2 disordER
Currently, the sequelae and short-term medical and psychological impact of the sars-cov-2 infection ("CoVID-19") remain poorly described.
- Trial name
- REHCOVER (NCT04443257)
- Testing
- assessment of the sequelae after hospitalization for Sars-COV-2
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Montpellier
SPG7
Consequences of Mutations in the SPG7 Gene at the Heterozygous State
Paraplegin, encoded by the SPG7 gene, is an ATP-dependent mAAA protease located in the inner mitochondrial membrane. Its function is not fully understood. Mutations in the SPG7 gene are responsible for spastic paraplegia type 7.
- Trial name
- CONSP-HET7 (NCT05127967)
- Testing
- Skin biopsy
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Montpellier
Heart Defects, Congenital, Adolescent
Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases
The investigators aim to measure the impact of a rehabilitation program in congenital cardiology in terms of health related quality of life.
- Conditions
- Heart Defects, Congenital, Adolescent, Young Adult
- Trial name
- QUALIREHAB (NCT03690518)
- Testing
- Cardiac rehabilitation
- Where
- 17 sites in France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Montpellier
Attention Deficit Disorder With Hyperactivity, Attention-Deficit-Disordered Children
Evaluation of a Parent/Child Cognitive-Behaviorial Therapy Program in ADHD Children With Emotional Dysregulation Profile
Attention Deficit Disorder (ADD) with or without Hyperactivity/Impulsivity (ADHD) is a neurodevelopmental syndrome that has a lasting impact on the child's daily lifestyle and leads to functional impairment.
- Trial name
- DP-KID (NCT03176108)
- Testing
- Cognitive Behavorial Therapy (CBT), Body mediation
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Montpellier
SARS-Cov-2 Infection, Rheumatoid Arthritis
Deciphering a Specific Signature of the Immunosenescence Induced in COVID-19+ Patients Versus Rheumatoid Arthritis Patients
Immune aging or immunosenescence is characterized by a loss of T cell clonal diversity and a contraction of naïve T cells with proliferative capacity associated with the functional impairment of many others immune cells as well…
- Trial name
- SENO-COVID (NCT04880720)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Univentricular Heart, Children, Adult
Respiratory Drive in Patients With Univentricular Congenital Heart Disease
The aim is to evaluate the correlation between the respiratory control to hypercapnia at rest and the VE/VCO2 slope measured during cardiopulmonary exercise testing.
- Trial name
- NCT03818373
- Testing
- polysomnography
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Fibres Supplementation in Rheumatoid Arthritis
Design: Randomized, double-blind, placebo-controlled study with 4 weeks of treatment with either fiber supplements or placebo. Primary outcome: variation in SCFA between baseline and week 4.
- Trial name
- SUPER-FIBRES (NCT04421313)
- Testing
- Dietary Fiber Supplementation
- Where
- France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis
ADIPOA - Clinical Study
Primary: To study the safety of a single injection of autologous adipose derived mesenchymal stromal cells (ASCs) on patients with moderate or severe osteoarthritis of the knee (OA).
- Trial name
- NCT01585857
- Testing
- Autologous adipose derived stem cells administrated for intra-articular use
- Where
- 2 sites in France, Germany
- Volunteers
- 18 people
- Sponsor
- University Hospital, Montpellier
Leukemia
Physical Activity Adapted at Home Supervised by Videoconferencing in Post-cancer for Children / AYA Treated for Leukemia (ONCOPED SAPATIC)
Leukemia is the most common form of cancer (29%) in children, adolescents, and young adults (AYA) (CNIB Report, 2017). Current treatments for leukemia (conventional chemotherapy or hematopoietic stem cell transplantation) can…
- Trial name
- NCT04136665
- Testing
- Physical Activity Adapted program
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Alcoholic Cirrhosis, Alcoholic Liver Disease
Value on Survival of Liver Volume After an Acute Decompensation of an Alcoholic Cirrhosis
Investigator seek to determine whether the volume of the liver can predict the survival after a decompensation of a patient suffering from chronic liver disease caused by excessive alcohol consumption (or alcoholic cirrhosis).
- Trial name
- PROLIV (NCT03508388)
- Where
- France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia
Treatment of Negative Symptoms and Schizophrenia
The aim of this study is to evaluate the therapeutic efficacy of a neuromodulation technique, tDCS (transcranial direct current stimulation) used as a complementary treatment on negative symptoms.
- Trial name
- STICCS (NCT02204787)
- Testing
- transcranial direct current stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis
Impact of Hand Osteoarthritis on Arterial Stiffness
Patients affected by osteoarthritis (OA) have an increase overall mortality compared to the general population, mainly due to cardiovascular diseases.
- Trial name
- NCT02167906
- Testing
- arterial stiffness measurement
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Renal Transplantation
Endothelial Microparticules and Antibody Mediated Rejection and Kidney Transplantation: Biomarker of Antibody-mediated Rejection in Kidney Transplantation
Context and rationale: Antibody-mediated rejection is the leading cause of long-term renal graft loss. It's due to the production by the recipient of antibodies directed against antigens (belonging or not to the HLA system)…
- Trial name
- MICROMARK RJ (NCT03098238)
- Testing
- Biological sample
- Where
- France
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Pronation-Supination of the Forearm, Impairment of
4 Dimensional - Impairment of Posttraumatic Forearm Rotation Evaluated With Computed Tomography
The aim of this study is to develop a 4D-CT (4 Dimensional Computed Tomography) -scan acquisition method for estimating the cause of posttraumatic impairment of the forearm.
- Trial name
- 4D-IRECT (NCT04067232)
- Testing
- 4D-CT-scan
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Montpellier
Poliomyelitis Sequelae
Characterization of the Immunological Profile Patients With Post-polio Syndrome
Many patients with polio sequelae have persistent and progressive worsening more than 15 years after the initial damage, with loss of muscle strength, asthenia and musculoskeletal pain.
- Trial name
- NCT03396783
- Testing
- blood test, electromyogram and walk test
- Where
- France
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Patellofemoral Dislocation
Assessment of Surgical Correction of Patello-femoral Instability by EOS 3D Kinematics
Assessment of surgical correction of patello-femoral instability by EOS 3D kinematics
- Trial name
- EOS-FP2017 (NCT04143438)
- Testing
- EOS 3D imaging protocol pre- and post-surgery
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Montpellier
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