Clinical trials: sponsored by University Hospital, Montpellier
Schizophrenia, Apathy
Study of the Effectiveness of Mental Contrasting and Implementation Intention in the Management of Apathy in Schizophrenia
Schizophrenia is a mental pathology that concerns 1% of the French population, characterized by heterogeneity of symptoms. One of them, apathy is defined as a multidimensional psychopathological state manifested by a decrease in…
- Trial name
- COMEIA (NCT04781179)
- Testing
- CM-II, Psychoeducation
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Montpellier
Dental Caries
Telemedicine and Forensic Odontology
The aim of this study is to identify the expectations of experts in forensic odontology on telemedicine. This study could improve, in multiple cases post mortem body identification.
- Trial name
- NCT05305157
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Traumatic Brain Injury
Prevalence, Severity, Risk Factors, and Prognostic Value of Hyponatremia in Patients With Traumatic Brain Injury
Hyponatremia (HN) is the most common electrolytic disorder in the traumatic brain injury (TBI) population, found in 17 to 51% of patients according to the series.
- Trial name
- WATERWAR (NCT05301049)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Montpellier
Sleep Apnea Syndromes
CPAP Observance During the COVID-19 (SARS-CoV-2) Pandemic
The hypothesis of this work is that the COVID 19 pandemic and the associated lockdowns are likely to modify the adherence to positive airway pressure (PAP) treatments among patients with sleep apnea.
- Trial name
- COVADENE (NCT04775966)
- Where
- France
- Volunteers
- 8,477 people
- Sponsor
- University Hospital, Montpellier
Myocardial Function, Echographic Parameters Obtaind by Speckle Tracking
Study of Myocardial Function by Speckle Tracking After Cancer Treatment With Anthracyclines in Childhood
The main goal of this study is to compare the values of echocardiographic parameters obtained by Speckle Traking analysis on myocardial function among patients under 18 years treated with anthracyclines in childhood, with healthy…
- Conditions
- Myocardial Function, Echographic Parameters Obtaind by Speckle Tracking, Chilhood Cancers
- Trial name
- SPECKLEANTHRA (NCT02893787)
- Testing
- Speckle Tracking Echocardiography
- Where
- France
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Metabolic Acidosis
Value of Fetal Scalp Lactate Sampling During Labour in Cases of Abnormal Fetal Heart Rate
ST-analysis of the foetal ECG (STAN®) is another second line technique for intrapartum foetal monitoring. Combining ST-analysis with standard CTG interpretation aims to identify hypoxic foetuses more accurately than CTG alone.
- Trial name
- NCT05259202
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Infertility
Using Embryo Organoids to Discover Human-specific Mechanisms of Preimplantation Embryo Development and Early Pregnancy
EMBRYOx study aims to establish and validate the use of trophoblast organoids (embryoids) from trophoblast placental stem cells as a 3D research model in understanding further preimplantation embryo development in vitro.
- Trial name
- EMBRYOx (NCT05231551)
- Testing
- Placental tissues
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Montpellier
Breastfeeding
Microchimeric Cell Tranfer From Mother to Child - Pilo Study
Microchimeric cells are known to be transferred from mother to child through the placenta. However it has been postulated that they could also be transferred through breastfeeding.
- Trial name
- NCT05250219
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Cirrhosis, Mechanical Ventilation Complication
Extubation Failure in Critically Ill Cirrhotic Patients.
Although a life-saving intervention, invasive mechanical ventilation (MV) prone to complications and side effects. Cirrhotic patients with a need of prolonged MV have a poor prognosis in ICU compared to general population of…
- Conditions
- Cirrhosis, Mechanical Ventilation Complication, Critical Illness
- Trial name
- FREELIVER (NCT05244005)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia
Assessment of the Efficacy of a Fatigue Management Therapy in Schizophrenia
Fatigue is commonly experienced in numerous pathologies, including schizophrenia. Research has shown that chronic fatigue can exacerbate clinical symptoms.
- Trial name
- ENERGY (NCT04332601)
- Testing
- Fatigue Management Therapy, TAU (Treatment as usual)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Dental Caries, Hydroxyapatite
Study of People's Profile Living in France Who Could be Interested in the Use of a Nanohydroxyapatite Toothpaste
Nano-hydroxyapatite is an interesting candidate to be a substitute for fluor in toothpastes or a complement to fluorides in order to prevent caries.
- Trial name
- NCT05234060
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
HCC
Non Transplantable Recurrence After Percutaneous Thermal Ablation of HCC
Percutaneous thermal ablation (PTA), resection and liver transplantation (LT) are the standard curative options for hepatocellular carcinoma (HCC). LT yields the best long-term outcomes but is limited by graft shortage.
- Trial name
- NCT05202184
- Testing
- Percutaneous thermal ablation
- Where
- France
- Volunteers
- 213 people
- Sponsor
- University Hospital, Montpellier
Rhizarthrosis, Arthritis
Post-operative Results of the Trapezometacarpal (TMC) Prosthesis for Advanced Pre-operative Deformities
Trapezometacarpal protheses are implanted for patients with trapezometacarpal arthritis. Having a pre-operative thumb adduction angle of less than 25 degrees with hyperextension, meaning a " Z-deformity " are somehow a reason to…
- Trial name
- NCT05169099
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Eating Disorders
Randomized Study Assessing a Program of Body Dissatisfaction Psychological Care in Eating Disorders
Eating disorders (ED) are a major public health problem for which current treatments are insufficiently effective. The transdiagnostic approach of eating disorders highlights body dissatisfaction (BD) as a major factor in the…
- Trial name
- INCCA (NCT05227625)
- Testing
- body dissatisfaction management group, Relaxation Group
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Ventricular Failure
Inter-observer Reproductibility of Visual Estimation of Left Ventricular Ejection Fraction in Critical Care
Inter-observer reproductibility of visual estimation of left ventricular ejection fraction is known to be good in cardiology but has not been studied in ICU.
- Trial name
- NCT04978389
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Shock
Central Venous Oxygen Saturation and Carbone Dioxide (CO2)-Derived Indices in the Critically:
The optimal management of shock states requires a precise evaluation of several parameters, clinical, biological, hemodynamic, and echocardiographic.
- Trial name
- NCT05220696
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Purify Antigen-specific B Cells From Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of autoantibodies directed against citrullinated proteins, called ACPAs.
- Trial name
- CURE RA (NCT05203952)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Aortic Coarctation, Congenital Heart Disease
Contribution of Multimodal Imaging in Early Coarctation
The CT-Coarct-PED study is a multicentred observational study aiming to describe the population of early coarctation during the last 10 years in South of France.
- Trial name
- CT-COARCT-PED (NCT05203874)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Montpellier
Dental Caries, Pregnancy Related
Oral Health and Pregnancy
The aim of this study is to identify the knowledge, behavior and social representation on dental health among pregnant women. This study could improve, in the future, prevention, treatments and care for them.
- Trial name
- OHAP (NCT04992754)
- Testing
- psychotherapy, lifestyle counseling
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Dental
Evaluation of Emergency Department Visits and Activity : Study
The main objective will be to evaluate the type of care performed and the main reasons for consulting patients for an odontological emergency in order to better adapt to the flow and expectations of patients.
- Trial name
- EOTDES (NCT05116631)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
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