Clinical trials: sponsored by University Hospital, Montpellier
Depression, History of Suicide Attempt
Behavioral Adaptation to Negative Social Cues in Depressed Patients According to Personal History of Suicide Attempt- COMPASS
Social interactions are part of daily life. To decide to interact with someone or not is a routine for humans. To ensure the quality of interpersonal relationships, emotional cues must be taken into account to adapt optimally the…
- Trial name
- COMPASS (NCT03898648)
- Testing
- Waiting room task
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases
Pre- or Per-dialytic Physical Exercise : a Cardioprotective Role?
This study aims at evaluating, in chronic kidney disease patients on dialysis, the effect of acute per- or pre-dialytic physical exercise on regional myocardial function and myocardial stunning, blood viscosity, arterial…
- Trial name
- EXP DIAL (NCT04831021)
- Testing
- Dialysis without physical exercise, Dialysis with pre-dialytic physical exercise, Dialysis with per-dialytic physical exercise
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease
New Biomarkers of Bone Mineral Metabolism as Cardiovascular Risk Factors in Chronic Kidney Disease Patients
To evaluate the relationships between bone mineral metabolism markers (osteoprotegerin, fibroblast growth factor 23) at inclusion and the occurence of cardiovascular events during a 7 year follow-up.
- Trial name
- NCT02808572
- Testing
- Plasma osteoprotegerin level, Plasma fibroblast growth factor 23 level, Vascular calcification score
- Where
- 7 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Covid-19, SARS-CoV Infection
RT-PCR Database Analysis for COVID-19 Infections and Re-infection
The SARS-Cov2 pandemic remains associated with many concerns. One of the them is the real frequency of likely re-infection and subsequently the level of protection conferred by the acquired immunity following primary-infection.
- Trial name
- ReCOV (NCT04653844)
- Where
- France
- Volunteers
- 7,000,000 people
- Sponsor
- University Hospital, Montpellier
Unipolar Depressed Outpatients, Mild Severity
Effectiveness of the First French Psychoeducational Program on Unipolar Depression
Background. Major Depressive Disorder (MDD) is highly prevalent and was associated with greater morbidity, mortality (including suicide), and healthcare costs.
- Conditions
- Unipolar Depressed Outpatients, Mild Severity, Without Psychotic Features
- Trial name
- PURE (NCT02501226)
- Testing
- Treatment as usual, ENVIE psychoeducational program
- Where
- France
- Volunteers
- 332 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Vaccination Against Pneumococcal in Naïve Abatacept Rheumatoid Arthritis Patients
Is pneumococcal conjugate vaccine (which induces a T-dependent humoral response) more efficient than pneumococcal polysaccharide vaccine (which induces a T-independent humoral response) in RA patients treated with abatacept…
- Trial name
- VACINA (NCT02547493)
- Testing
- pneumococcal polysaccharide vaccine, pneumococcal conjugate vaccine, Abatacept
- Where
- 11 sites in France, Monaco
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Neurocognitive Disorders, Alzheimer Disease
Non Verbal Communication and Dementia
Cognitive impairements in Alzheimer's and apparented disorders may lead to the decreased engagement in activities, spetially in moderate and advanced stages of evolution.
- Trial name
- GEMAN (NCT04255329)
- Testing
- Montessori reading roundtable, Usual reading
- Where
- France
- Sponsor
- University Hospital, Montpellier
Diabetic Patients Type 1 and 2, Podologic Grade From 0 to 3
Transient Thermal Behavior and Diabetic Foot
In our study, the investigators propose to analyze the transient thermal responses taken at the level of the sole of the foot, following the application of a cold stimulus.
- Trial name
- PICOTE (NCT03872089)
- Testing
- Infrared Thermography
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Montpellier
Psychoactive Substance Use, Mood Disorders
PrEP and Consumptions
HIV pre-exposure prophylaxis (PrEP) with Truvada®, a combination of two antiretrovirals (tenofovir \& emtricitabine) is a prevention strategy for HIV-negative people at high risk of acquiring HIV.
- Trial name
- PrEP (NCT03449771)
- Testing
- self-administered questionnaire
- Where
- 5 sites in France
- Volunteers
- 237 people
- Sponsor
- University Hospital, Montpellier
Hearing Loss
Evaluation of the Global Auditory Nerve Activity for Exploration of Hearing in Humans
To date, all the electrophysiological methods for auditory testing rely on the measure on synchronous evoked auditory nerve activity.
- Trial name
- MELAUDI-2 (NCT03552224)
- Testing
- Recording of auditory nerve activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Systemic Autoinflammatory Diseases (SAID)
Evaluation of a New Sequencing Strategy in Autoinflammatory Siseases (BIOSAID)
Main objective: To compare the efficacy of a new strategy of Next Generation Sequencing (NGS) versus a classical Sanger strategy, for the diagnosis of patients referred to the laboratory for suspected systemic autoinflammatory…
- Trial name
- BIOSAID (NCT02976948)
- Testing
- No intervention
- Where
- France
- Volunteers
- 299 people
- Sponsor
- University Hospital, Montpellier
Parkinson Disease
A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease
This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game.
- Trial name
- RGP (NCT02855710)
- Testing
- Rhythm workers training Perceptive timing, Rhythm workers training sensorimotor timing, No Rhythm workers training
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Parkinson's Disease
Proof of Concept BeatPark
Physical activity has demonstrated its beneficial effect on functional capabilities and quality of life in patients with PD. However, the daily physical activity remains limited in these patients.
- Trial name
- BEATPARK 2 (NCT02647242)
- Testing
- Auto rehabilitation program of gait with Beat Health device.
- Volunteers
- 45 people
- Sponsor
- University Hospital, Montpellier
Stroke, Ischemic
Regional Strategy for Transfer for Mechanical Thrombectomy
A mono-centre observational study with the aim of compare clinical outcome at 3 month on patients admitted with recent cerebral infarct and intracranial large vessel occlusion in the anterior circulation who are eligible for…
- Conditions
- Stroke, Ischemic, Large Vessel Occlusion
- Trial name
- START (NCT04046757)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
Intensive Care
Mobility, Functional Autonomy and Respiratory Function After Prolonged Stay in Intensive Care Unit
The hospital survival of patients hospitalized after prolonged stay in intensive care unit has improved however there are a loss of functional autonomy and an impaired of peripheral and respiratory muscle performance, what leads…
- Trial name
- MAORI (NCT04319822)
- Testing
- blood sample and muscular biopsy
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Age Problem
Pathology of Helicases and Premature Aging: Study by Derivation of hiPS
Topic of this work is the involvement of replicative helicases in human premature ageing syndrome. Replicative helicases are ubiquitous and essential during numerous reactions of the DNA metabolism.
- Trial name
- HeliPS (NCT03898817)
- Testing
- taking of cutaneous cells
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Montpellier
Type1diabetes
Root Cause Determination of Catheter Obstructions
During this study, the investigators will perform a collection of biological and device samples (blood, catheters, insulin) in order to investigate the causes of catheter obstructions in patients with type 1 diabetes treated by…
- Trial name
- CATS (NCT03230266)
- Testing
- Collection of intra-peritoneal catheters for insulin infusion
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Montpellier
Metabolic Diseases
Use of the DBS for the Follow-up of Blood Clinical Parameters of Old People
It is about an interventional study.The use of the blotting paper called "Dried Blood Spot" or DBS is a method of systematic neonatal screening of the metabolic diseases.
- Trial name
- DBSage (NCT02440945)
- Testing
- Collection of blood
- Where
- France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Probable Alzheimer Disease, Parkinson Disease
In Vivo Alzheimer Proteomics
In France, an estimated 860 000 patients are affected by Alzheimer Disease (AD) which represents, as in other developed countries, a major public health issue.
- Conditions
- Probable Alzheimer Disease, Parkinson Disease, Neurological Disease Without Cognitive Degradation, Brain Trauma
- Trial name
- PROMARA (NCT02263235)
- Testing
- administration of stable isotope-labelled leucine-, collection of CSF, blood, urine, saliva
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Montpellier
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