Clinical trials: sponsored by University Hospital, Montpellier
In Vitro Fertilization (IVF), Infertility
Working IVF Patients' Quality of Life
Infertility affects approximately 1 in 6 couples and may require the use of Medically Assisted Reproduction techniques. In France, there were more than 60,000 in vitro fertilization (IVF) attempts in 2016.
- Trial name
- WIQoL (NCT04966091)
- Testing
- Completion of questionnaires
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Luteal Phase Insufficiency
Early Luteal Phase Progesterone Kinetics After hCG-Induced Ovulation in Modified Natural Cycle
This pilot study evaluates how progesterone levels change after hCG-triggered ovulation in modified natural cycles. Forty women preparing for frozen embryo transfer will have blood tests over 6 days to monitor hormone levels.
- Trial name
- CineP4 (NCT07028710)
- Testing
- hCG
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Breast Cancer
Impact of Video Information Support on Preoperative Anxiety in Breast Cancer Surgery
The medical information delivered to the patient before any surgery constitutes an essential and compulsory step during the initial management of the operated patient.
- Trial name
- SENEDOP (NCT05350527)
- Testing
- Consultation of a Web Platform
- Where
- 4 sites in France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Montpellier
Pediatric Tumor, Familial Cancer
Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia
Background. Cancer is the leading cause of death by disease in children. Most pediatric tumors differ from adult tumors in terms of biological and clinical characteristics.
- Conditions
- Pediatric Tumor, Familial Cancer, Solid Tumor, Childhood, Hematological Tumor
- Trial name
- ALADIN (NCT04471961)
- Testing
- Exome sequencing in pediatrics cancers
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Obesity, Bariatric Surgery
The Impact of the Hypnosis on the Loss of Weight at Patients in Failure of Bariatric Surgery
The therapeutic problem of obesity is weight control, a major difficulty, involving a significant change in eating behavior. A number of studies show that there are many factors of resistance to weight loss whether they are…
- Trial name
- BARIATHYPNOSE (NCT03485469)
- Testing
- Hypnosis, Standard Care
- Where
- 5 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Cervical Cancer Stage IA1, Cervical Cancer Stage IB1
Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Cervical cancer is a rare pathology. Recent studies showed that the risk of recurrence is higher for patients treated by coelioscopy in comparison with laparotomy.
- Conditions
- Cervical Cancer Stage IA1, Cervical Cancer Stage IB1, Cervical Cancer Stage IA2, Cervical Cancer Stage IB2
- Trial name
- CTC-COL (NCT04770090)
- Testing
- Blood samples
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Woman of Reproductive Age, Socioeconomic Factors
Understanding Cycles to Improve Women's Health
Introduction: The C-HEALTH study investigates how environmental and socio-economic conditions affect women's menstrual cycles and reproductive health.
- Trial name
- C-HEALTH (NCT07037082)
- Testing
- Self-saliva sampling, Self-collection of dried blood spots, Wearing the connected ring
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obesity, Morbid, Bariatric Surgery Candidate
Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery
The aim of this cohort is to evaluate the follow-up of morbidly obese patients treated by several types of bariatric procedures.
- Trial name
- BAREVAL (NCT02310178)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Montpellier
Alcohol Associated Liver Disease, Liver Transplantation
ADDICTOlogical Intervention in LIVEr Transplantation Recipients
Transplantation for end-stage-liver disease (ESLD) in the context of Alcohol-Associated Liver Disease (AALD) has been increasing and represents the main indication for Liver Transplantation (LT) in the world.
- Trial name
- AddictoLIVE (NCT06472973)
- Testing
- Post-transplant addiction intervention
- Where
- 16 sites in France
- Volunteers
- 720 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Neoplasms
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology
Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common examination for all patients with…
- Trial name
- PanEXPEL2 (NCT04370574)
- Testing
- Soluble Biomarkers dosage
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Colorectal Cancer, Liver Metastases
French Assessment of MRD by Liquid Biopsies in Colorectal With Liver Metastasis Patients (FRENCH.MRD.CRLM)
Improving personalized cancer treatments and finding the best strategies to treat each patient relies on using new diagnostic technologies.
- Conditions
- Colorectal Cancer, Liver Metastases, Stage IV Colorectal Cancer, Minimal Residual Disease
- Trial name
- NCT06287723
- Testing
- Blood sample/Liquid biopsy
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Nsclc
Residual Disease Evaluation of Resected NSCLC by cirDNA Analysis
Prognosis of resectable early stages NSCLC might be improved by a better knowledge of post-operative minimal residual disease (MRD).
- Trial name
- LUNGDOC (NCT05165160)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Montpellier
Hematologic Malignancy
Prospective Cohort With Hemopathy in Languedoc-Roussillon
Prospective Cohort Study of clinical and laboratory data of patients with hemopathy.
- Trial name
- HemoDiag (NCT02134574)
- Testing
- hematologic malignancy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Hepatocellular Carcinoma
Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial
Following the results of study IMbrave150, the combination Atezolizumab + Bevacizumab is a promising treatment option for patients with HCC.
- Trial name
- AB-LATE02 (NCT04727307)
- Testing
- Atezolizumab (neoadjuvant), Percutaneous Radiofrequency, Bevacizumab (adjuvant)
- Where
- 19 sites in France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Ductal Adenocarcinoma
Distal Pancreatectomy, Minimally Invasive or Open, for Malignancy (DIPLOMA)
Objective: To compare MIDP with ODP regarding radical resection rate for pancreatic ductal adenocarcinoma (PDAC) in the pancreatic body or tail.
- Trial name
- DIPLOMA (NCT04483726)
- Testing
- minimally invasive distal pancreatectomy, open distal pancreatectomy
- Where
- 5 sites in France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Montpellier
Pregnant With Complication, Twin Pregnancy With Antenatal Problem
Twin Pregnancy Cohort
The investigators know that multiple factors are involved in the risk of obstetric complications. The twin pregnancy model appears to be an interesting model for a bio-statistical analysis of data collected in the context of a…
- Trial name
- COGEM (NCT05144321)
- Testing
- Impact of environment upon obstetrical, neonatal and maternal adverse outcome
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Hypercapnic Acidosis
Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis
The purpose of this study is to determine whether nasal high flow is non inferior to non invasive ventilation (NIV) in the early treatment of patients with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) and…
- Conditions
- Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Hypercapnic Acidosis, Respiratory Failure With Hypercapnia
- Trial name
- HiCOPD (NCT06114667)
- Testing
- Ventilatory support via nasal high flow, Ventilatory support via NIV
- Where
- 3 sites in France
- Volunteers
- 174 people
- Sponsor
- University Hospital, Montpellier
Acute Myeloid Leukemia
Expectations of Patients in Palliative Situation
To date, there is a lack of data about the benefit of blood cell transfusions for patients diagnosed of a hematologic malignancy who are not eligible for curative treatments.
- Trial name
- ERAPH (NCT06786897)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Aromatase Inhibitors
Assessment of Cryotherapy's Analgesic Impact in Anti-aromatase-induced Arthralgia
The first aim of this comparative, randomized, prospective, multicenter study is to evaluate the analgesic effect at 6 weeks of whole-body cryotherapy, compared to placebo cryotherapy, in patients suffering from arthralgia under…
- Trial name
- CRYOMATASE (NCT05315011)
- Testing
- Whole-body cryotherapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Montpellier
Transplant; Failure, Liver, Addiction, Alcohol
Addiction Intervention in Liver Transplantation Candidates
Addiction care is "a la carte treatment", adapted to the motivation and time constrains of users. Thus, various types of psychotherapeutic follow-up can be considered, different addictolytic medications or opioid maintenance…
- Trial name
- Addictolive (NCT05322226)
- Testing
- Addiction follow-up before and after liver transplantation
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
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