Clinical trials: sponsored by University Hospital, Montpellier
YY1 Related Disorder
Better Delineation of YY1 Related Phenotype and Epigenetic Signatures.
YY1 related disorder, also known as Gabriele-de-Vries syndrome, is mainly characterised by developmental delay (DD) and intellectual disability (ID), ranging from mild to severe, and neuroimaging abnormalities.
- Trial name
- NCT04381715
- Testing
- Epigenetic signatures
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Diabetes
Optimizing Statin Tratment in People Living With Diabetes
Hypercholesterolemia is frequent (prevalence of 30% in general population) and constitue with diabetes, obesity and arterial hypertension a major risk factor of atherosclerosis that leads to cardiovascular diseases (CVD).
- Trial name
- MEDPHARM-RCV (NCT04320719)
- Where
- France
- Volunteers
- 387 people
- Sponsor
- University Hospital, Montpellier
Non-Alcoholic Fatty Liver Disease, Chronic Liver Disease
Combination Diagnostic Strategies in NAFLD
Serial combination of biological and elastography tests is accurate to diagnosing advanced fibrosis in non-alcoholic fatty liver disease (NAFLD) patients.
- Trial name
- CombinationSSI (NCT04384159)
- Volunteers
- 577 people
- Sponsor
- University Hospital, Montpellier
Pancreatoduodenectomy
Outcome After Laparoscopic Versus Open Pancreaticoduodenectomy
Aim of the study : To determine the morbimortality of Laparoscopic pancreaticoduodenectomy (LPD) compared to the gold standard Open pancreaticoduodenectomy approach (OPD).
- Trial name
- PaMIvOP (NCT04381702)
- Testing
- Pancreatoduodenectomy
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Mechanical Ventilation, SARS-CoV-2
Transpulmonary Driving Pressure in ARDS COVID19 Patients
A majority (65-85%) of critically ill patients admitted in intensive care units with a confirmed diagnostic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) developed an acute respiratory distress syndrome (ARDS)…
- Conditions
- Mechanical Ventilation, SARS-CoV-2, COVID-19
- Trial name
- TRANSPULMONARY (NCT04381286)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Caregivers, COVID-19
Barrier Measures to Limit Covid-19.Nosocomial Transmission: a Cross-sectional Evaluation
Use lay language. The Covid-19 pandemic hit France in March 2020 and stage 3 of the epidemic justified the introduction of national and unprecedented containment measures from March 17, 2020.
- Trial name
- EMBELLIE (NCT04376944)
- Testing
- Survey
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
HCC
Small and Steatotic Hepatocellular Carcinoma
Percutaneous thermoablation in an effective local curative treatment in patients with cirrhosis and HCC smaller than 3 cm in diameter (BCLC 0-A).
- Trial name
- NCT03428321
- Where
- France
- Volunteers
- 238 people
- Sponsor
- University Hospital, Montpellier
Peyronie Disease
Medical Treatment of Peyronie's Disease With Collagenase Clostridium Histolyticum
Peyronie's disease is the appearance of a fibrosis plaque on the albuginea of the corpora cavernosa, which produces mechanical traction at the time of erection, inducing a deformation/curvature of the erect penis.
- Trial name
- NCT04370652
- Where
- France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Major Hepatectomy
Segment IV Hypertrophy After Liver Venous Deprivation
before major hepatectomy, in case of insufisant future liver remanent volume or function, portal embolization is a routinely used method to enable growth of the future liver remnant.
- Trial name
- NCT04370132
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Systemic Lupus Erythematosus, Lichen Planus
Telangiectatic Palmoplantar Keratoderma in Systemic and Subacute Lupus Erythematosus
Palmoplantar keratoderma (PPK) associated to livid telangiectatic erythema during systemic lupus erythematosus (SLE) and subacute cutaneous lupus erythematosus (SCLE) is a rare phenomenon seldom reported in literature.
- Trial name
- NCT04356014
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Montpellier
PDAC of the Body and the Tail of the Pancreas, CR- POPF
Oncologic Impact of Pancreatic Fistula
Clinically-relevant post-operative fistula is a major complication after DP, but it did not affect post-operative therapeutic path nor oncologic long-term outcomes.
- Trial name
- POPF-DSS (NCT04348084)
- Where
- France
- Volunteers
- 382 people
- Sponsor
- University Hospital, Montpellier
Low-grade Glioma
Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas
Retrospective longitudinal follow-up in patients with diffuse low-grade glioma with multimodal MRI assessment
- Trial name
- SPECIFY (NCT04346472)
- Testing
- Repeated Measurements of the relative regional cerebral blood volume
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia
Cognitive Remediation Program for Family Caregivers in Schizophrenia
Cognitive impairments are extremely common in schizophrenia and strongly predict deficit in daily functioning, the poor managing medication and multiple hospitalizations.
- Trial name
- CIRCUS (NCT04173598)
- Testing
- Cognitive Adaptation Training for Caregivers (CAT Famille), Usual Care
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Cystic Fibrosis
Respiratory Function at Preschool Age of Children Detected of Cystic Fibrosis in Neonatal Period
The widespread neonatal detection of cystic fibrosis in France since 2002 permits to treat children from birth. New treatments used for young children involve to assess efficacy criteria specific to this population.
- Trial name
- REVOLMUCO (NCT02358798)
- Testing
- 3 years-assessment of respiratory function
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Atrial Fibrillation
Systematic Screening With Electrocardiogram for Unknown Atrial Fibrillation in 65 Years Old and Above People in Nursing Home
Atrial fibrillation is the most common arrhythmia. Some studies shown that systematic screening with electrocardiogram could improve atrial fibrillation detection. No studies are available in nursing home.
- Trial name
- NCT02892578
- Testing
- electrocardiogram
- Where
- France
- Volunteers
- 287 people
- Sponsor
- University Hospital, Montpellier
Hyperventilation Syndrome
Nasal Ventilation Versus Voluntary Hypoventilation in the Rehabilitation of Hyperventilation Syndrome
The main objective of this study is to measure the effect (at 3 months) of dyspnea control rehabilitation with nasal ventilation versus standard rehabilitation, in dyspneic patients with hyperventilation syndrome.
- Trial name
- RehabSHV (NCT03159429)
- Testing
- Standard rehabilitation, Nasal breathing rehabilitation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier
Severe and Symptomatic Aortic Stenosis
Long-term Clinical and Echographic Follow-up (More Than 4 Years) After TAVI.
Transcatheter Aortic Valve Implantation (TAVI) is became the gold-standard therapy for patients with severe and symptomatic aortic stenosis with high operative risk or not suitable for surgery.
- Trial name
- NCT03402724
- Testing
- echographic
- Where
- France
- Volunteers
- 178 people
- Sponsor
- University Hospital, Montpellier
Orthopaedic Surgery
Remote Controlled Analgesia on Patient Experience
The main objective of this study is to compare the efficacy of continuous nerve blocks with single injection in terms of perioperative patient satisfaction after scheduled orthopedic ambulatory surgery.
- Trial name
- R-CAPE (NCT02720965)
- Testing
- Remote-controlled perineural local anesthetics delivery
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Non Small Cell Lung Cancer
Texture Features and PDL1 in CT-PET 18 FDG
Search correlation between texture features in CT-PET 18 FDG and overexpression of PDL1 in non-small cell lung carcinomas during the inital staging.
- Trial name
- NCT04309422
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Montpellier
Arthritis, Juvenile Rheumatoid
Identification of Genes Involved in Juvenile Idiopathic Arthritis by Wholel Exome Sequencing
Juvenile idiopathic arthritis (JIA) is considered to be a multifactorial disease caused by a combination of environmental factors and predisposing genetic factors.
- Trial name
- GenesinJIA (NCT02067962)
- Testing
- Blood sample
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
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