Clinical trials: sponsored by University Hospital Tuebingen
Emergence Delirium, Postoperative Delirium
Verification of a New Predictive Delirium Score in Adults With Elective Cardiac Valve or Bypass Surgery With Perioperative Use of a Heart-lung Machine; a Monocentric Pilot Observational Study
Basics (state of scientific knowledge): Delirium is an acute disturbance of consciousness and attention that develops over a short period of time and fluctuates in severity.
- Trial name
- MO-FA2-(TB) (NCT07276503)
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
PARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)
Dual-task Cognitive-motor Telerehabilitation in Persons With PD-MCI
Telerehabilitation is a promising tool for treating and preventing further disease progression in Parkinson's disease (PD) [1, 2].
- Trial name
- HomeFitPD (NCT07411365)
- Testing
- Dual-task Cognitive Motor Training, Cognitive Motor Training
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University Hospital Tuebingen
Rectal Cancer
Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive Radiotherapy
This study is testing whether radiation delivered with MRI guidance using a so-called MR-linac in distal rectal cancer can result in a high rate of organ preservation.
- Trial name
- MARS (NCT07337876)
- Testing
- Dose escalated radiotherapy using a 1.5 T MR-Linac
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
TNBC - Triple-Negative Breast Cancer
Immunotherapy-related CRP Kinetics in Early and Metastatic Triple-negative Breast Cancer
ICK-breast is a prospective, multicentric, non-interventional investigator-initiated trial (IIT) that aims to investigate the prognostic value of CRP kinetics in early and advanced or metastatic triple negative breast cancer…
- Trial name
- NCT05914961
- Where
- Germany
- Volunteers
- 225 people
- Sponsor
- University Hospital Tuebingen
Delivery Mode
Individual Choice of Delivery Mode
The primary aim of the study is to investigate personal attitudes regarding mode of delivery among both medical health care professionals and non-professionals.
- Trial name
- NCT03131830
- Testing
- Online-based questionnaire
- Where
- Germany
- Volunteers
- 2,605 people
- Sponsor
- University Hospital Tuebingen
Diabetes (DM), Prediabetes
Artificial-Intelligence-based Early Detection of Diabetic Retinopathy (FUNDUS AI)
Examination of individuals with prediabetes and established diabetes for early signs of diabetic retinopathy.
- Trial name
- FUNDUS AI (NCT07378891)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
Gynecological Malignancies, Cervical Cancer
Immunotherapy-related CRP Kinetics in Metastatic Gynecological Malignancies
ICK-Gyn is a prospective, multicentric, non-interventional investigator-initiated trial (IIT) that aims to investigate the prognostic value of CRP kinetics in advanced or metastatic gynecological malignancies under immune…
- Conditions
- Gynecological Malignancies, Cervical Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT05914974
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Excessive Musculoskeletal Stress
Save Our Surgeons - Differences in Stress of Robot-assisted Laparoscopic Surgery vs. Conventional Laparoscopic Surgery
Monocentric trial to evaluate differences in musculoskeletal and cognitive stress of robot-assisted laparoscopic surgery (RALS) vs. conventional laparoscopic surgery (CLS).
- Trial name
- SOSII (NCT04352452)
- Testing
- laparoscopic surgery
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- University Hospital Tuebingen
Hormone Receptor Positive HER-2 Negative Breast Cancer
Impact of Endocrine Therapy, Menstrual Cycle, PAM50, Ki67 on Treatment Decisions in HR+ and HER2- Breast Cancer
PEAK is a prospective, multicenter, non-interventional investigator-initiated trial (IIT) that aims to investigate the influence of the menstrual cycle phase on Ki67 in patients who either receive Tamoxifen, Aromatase inhibitors…
- Trial name
- NCT05878314
- Where
- Germany
- Volunteers
- 504 people
- Sponsor
- University Hospital Tuebingen
Detection of Surgical Smoke Gas Using AI
AI-Based Real-Time Detection of Surgical Smoke Using Endoscopic Data
The goal of this observational, prospective monocentric pilot study is to generate a pilot dataset to train a computer-assisted model for automatic, intraoperative detection of surgical smoke gas.
- Trial name
- NCT07397000
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
ALL, Childhood B-Cell, Acute Lymphoid Leukemia Relapse
Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia
The objective of the trial is to evaluate the safety, clinical toxicity and in vivo immunological effects of MOR00208 in pediatric patients with acute lymphoblastic leukemia who showed newly emerging or persistent MRD after a…
- Conditions
- ALL, Childhood B-Cell, Acute Lymphoid Leukemia Relapse, Acute Lymphocytic Leukemia Refractory
- Trial name
- Anti-CD19-ALL (NCT05366218)
- Testing
- Tafasitamab
- Where
- 11 sites in Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Crohn Disease, Nutrition Assessment
Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients
Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is on the rise globally. Although medical treatments have advanced, CD still leads to significant health issues due to disease progression and medication side…
- Conditions
- Crohn Disease, Nutrition Assessment, Diet Therapy
- Trial name
- CONSISTENT (NCT06953791)
- Testing
- aCDED + Modulen, Prednisolone
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University Hospital Tuebingen
Advanced/Metastatic Breast Cancer, Breast Cancer (Early Breast Cancer)
Praegnant Breast Cancer: Early/Advanced/Metastatic
Among patients with breast cancer the subgroup of patients with metastases are considered the group of patients with the worst prognosis.
- Trial name
- PRAEGNANT (NCT02338167)
- Testing
- Blood sampling
- Where
- 61 sites in Germany
- Volunteers
- 13,500 people
- Sponsor
- University Hospital Tuebingen
Uterine Diseases
Prospective Data Collection to Compare RAL for Hysterectomies and Other Indications in to Conventional Laparoscopy
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- NCT05613816
- Testing
- Senhance Surgical System
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- University Hospital Tuebingen
Endometriosis
AI Based Real Time Detection of Endometriosis Lesions
Development of AI-based approaches for automated real-time detection of endometriosis lesions using endoscopic image and video material.
- Trial name
- NCT06873373
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- University Hospital Tuebingen
Musculoskeletal Diseases or Conditions
Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- ERCON (NCT06109753)
- Testing
- Robotically Assisted Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- Germany
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Breast Carcinoma, Breast Carcinoma in Situ
Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )
The present study aims to investigate the impact of Tumescent Local Anesthesia (TLA) on pain perception following surgeries typical for breast cancer.
- Trial name
- NCT06335108
- Testing
- General Anaesthesia, Local tumescent anaesthesia
- Where
- Germany
- Volunteers
- 349 people
- Sponsor
- University Hospital Tuebingen
Surgical Procedure, Unspecified
Electrosurgical Intervention Analysis: Comparing Procedure Patterns
The purpose of this prospective, single center study is to verify the hypothesis that each type of intervention creates a specific data pattern like a digital "fingerprint".
- Trial name
- NCT06873347
- Testing
- Procedure type
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- University Hospital Tuebingen
Pregnancy
Reducing False Positives in Prenatal Screening
Combined first-trimester screening represents the gold standard of risk assessment for the presence of trisomy 21, 18, and 13. The concept is based on the age risk, the measurement of fetal nuchal translucency (NT), and the…
- Trial name
- ReFaPo02 (NCT03375359)
- Testing
- cfDNA screening
- Where
- Germany
- Volunteers
- 1,127 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Resolve Infertility
Acceptance of Uterus Transplantation
Transplantation of an uterus
- Trial name
- NCT03048396
- Testing
- Uterus transplantation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen