Clinical trials: sponsored by University of Alabama at Birmingham
Onychomycosis, Dermatophytosis
Study Evaluating the Effect of Jublia on Dermatophytomas
This study will examine how Jublia affects dermatophytomas, which are difficult to treat with other therapeutic options.
- Trial name
- NCT03098615
- Testing
- Jublia (Efinaconazole 10% Topical Solution)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Multiple Sclerosis, Restless Legs Syndrome
Impact of Acute Leg Cycling at Various Intensities on RLS Severity in Persons With MS
The purpose of this study is to evaluate the impact of acute leg cycling conditions at three different intensities versus a control condition condition on symptoms of restless legs syndrome (RLS) in persons with multiple…
- Trial name
- NCT03849001
- Testing
- Exercise Conditions
- Sponsor
- University of Alabama at Birmingham
Multiple Sclerosis
A Study for Testing Text Messaging and Newsletter as a Strategy for Interrupting Sedentary Behavior
The study will examine the possibility of reducing sedentary behavior (SB) in African Americans with MS. SB consists of any waking activities that are done lying or sitting and do not demand significant physical effort (e.g.…
- Trial name
- SLMM (NCT03671499)
- Testing
- Social Cognitive Theory based text messages
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Catheter Related Complication
Fluoroscopic-Guided Micropuncture Technique for Common Femoral Artery Access
The main objective of this proposed study is to examine if oblique projection (20- degrees right anterior oblique (RAO) for right femoral artery access or 20-degree left anterior oblique (LAO) for left femoral artery access) is…
- Trial name
- ACCESS (NCT03955653)
- Testing
- Femoral artey access
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Type 2 Diabetes
A Specialized Diet for the Unique Metabolic Characteristics of Peripubertal African American Girls
A diet (42% carbohydrate) specialized to the unique metabolic characteristics of peripubertal African AMerican girls (hyperinsulinemic, low insulin sensitive) will be more effective in maintaining glucose and insulin homeostasis…
- Trial name
- PRIMO (NCT00718874)
- Testing
- Dietary
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Body Composition, Energy Balance
Bad Genes or Genes Behaving Badly
A key factor in the determination of body composition over the lifecourse is fat accumulation during childhood. Periods of life associated with the greatest changes in organ development and growth, i.e.
- Conditions
- Body Composition, Energy Balance, Metabolism
- Trial name
- NCT01041664
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bone Mineral Density, Body Fat Distribution
The Bone-Fat-Pancreas Axis in Children
The overarching hypothesis of this proposal is that obesity and positive energy balance in children promote both low bone mass accrual and risk for diabetes through events that are mechanistically associated and that involve bone…
- Conditions
- Bone Mineral Density, Body Fat Distribution, Insulin Homeostasis
- Trial name
- NCT01041898
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fasting Blood Measures, Body Scans
Mediators of Kidney-Bone Communication in Childhood
An identified hormone linking bone and kidney function is Fibroblast Growth Factor-23 (FGF23). Data on the variation of FGF23 levels for bone and mineral metabolism in children are scarce.
- Trial name
- PAKC (NCT02040740)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Changes in Bone Mineral Content, Changes in Bone Marrow Adipose Tissue
Tissue Partitioning in Early Childhood
Early childhood (~4-6 years of age) is an important window for determining body composition trajectory and may be a critical period for the development of tissue partitioning patterns that influence later disease risk, including…
- Trial name
- NCT01041794
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Metabolism
Critical Periods of Exercise
Early childhood (~3-7 years of age) is an important window for determining body composition trajectory and may be a critical period for the development of tissue partitioning patterns that influence obesity risk.
- Trial name
- NCT01041820
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Puberty Related Intervention to Improve Metabolic Outcomes (The PRIMO Study)
Puberty represents a critical period in terms of metabolic health. Racial differences in insulin dynamics, reproductive maturation, and the associated endocrine changes may affect a female's health later in life.
- Trial name
- PRIMO (NCT01410643)
- Testing
- Macronutrient Modification
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gout
Virtual Gout Clinic
The overarching goal of the investigators project is to identify best practices in gout and hyperuricemia management, translate these evidence-based practices into a highly generalizable strategy for optimal delivery of gout…
- Trial name
- NCT02790463
- Testing
- Pharmacist-Led Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,463 people
- Sponsor
- University of Alabama at Birmingham
Cervical Cancer, Healthy Diet
HPV Vaccination Among Daughters of Latina Immigrants
The overall goal of this study to promote HPV vaccine uptake among daughters of Latina immigrants between the ages of 9 and 12.
- Trial name
- NCT04154319
- Testing
- HPV Vaccination, Healthy Eating
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tobacco Use Cessation
Gender-Relevant Tobacco Cessation Among Women in Brazil
The overall goal of this renewal is three-fold: (1) to continue to sustain and strengthen the network; (2) to conduct a group randomized controlled trial to assess the efficacy of a theory-based, culturally- and gender-relevant…
- Trial name
- NCT03845413
- Testing
- Control, 12-home visits by the Community Health Worker + referring to an appointment for the participant to attend the tobacco cessation program
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Opioid-Related Disorders, Opioid Withdrawal
Comparison of Three Opioid Detoxification Treatment Regimens
Despite an increased focus on treating opioid use disorder there are relatively few studies that compare the length of time required for detoxification with medications other than buprenorphine.
- Trial name
- NCT03678792
- Testing
- Buprenorphine/naloxone, Morphine, Tramadol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Chronic Low Back Pain
Chronic Low Back Pain Graded - Exposure Psychoeducation Intervention
This study will examine the effectiveness of one of two psychoeducation treatments on chronic low back pain.
- Trial name
- VRGE (NCT03909048)
- Testing
- Interactive - Psychoeducation, Non-interactive Psychoeducation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Metastatic Breast Cancer
Study of Avastin (Bevacizumab) to Reverse Acquired Estrogen Independence in Previously Hormone Responsive Metastatic Breast Ca.
The purpose of this study is to determine if acquired hormone therapy resistance can be reversed by Avastin (Bevacizumab), as measured by time to disease progression and evaluate toxicity of the combination of hormone treatment…
- Trial name
- NCT00240071
- Testing
- Avastin, Hormonal therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Gout
Novel Methods for Ascertainment of Gout Flares -A Pilot Study
The purpose of this study is to determine the feasibility and acceptability of using different remote data collection technologies to ascertain flare occurrence among gout patients.
- Trial name
- NCT02855437
- Testing
- IVR (Phone call), RheumPro (Smartphone application)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Actual Electronic Cigarette Use
Secondary data analysis will be performed as our approach to complete the study. A nationally representative dataset (BRFSS, 2017) will be used to answer the above hypotheses.
- Trial name
- NCT04135404
- Testing
- health-related telephone surveys
- Volunteers
- 400,000 people
- Sponsor
- University of Alabama at Birmingham
Car Seat Installation
Improving Child Restraint Installation
The investigators will conduct a pre-post trial with 150 parents in rural South Central Montana. The study will recruit families to cooperating community locations (e.g., churches, public libraries) to participate in research…
- Trial name
- NCT03508843
- Testing
- interactive virtual presence
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham