Clinical trials: sponsored by University of Bern
Healthy, Mild Cognitive Impairment
tES Effects on Associative Memory Performance
Previous studies showed that transcranial electric stimulation (tES) applied over the prefrontal cortex improves cognitive performance in healthy elderly adults as well as in patients suffering from mild cognitive impairment or…
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03351452
- Testing
- real anodal transcranial direct current stimulation, real transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Memory Impairment
The Effect of tES on a Cognitive Training
The aim of this study is to investigate the effect of a transcranial electrical stimulation (tES) on a cognitive training in healthy elderly and memory impaired participants.
- Trial name
- NCT03475446
- Testing
- real anodal tDCS healthy elderly, real tACS healthy elderly, real anodal tDCS MCI
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Bern
Adjustment Disorders
Internet-based Self-help for Negative Life Events
The purpose of the study is to investigate the efficacy of an internet-based self-help intervention for dealing with stressful life events.
- Trial name
- ZIEL (NCT03379155)
- Testing
- Internet-based self-help program
- Where
- 2 sites in Switzerland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Bern
Congenita Nasolacrimal Duct Obstruction, Preterm Neonates
Euphrasia Eye Drops in Preterm Infants With First Signs of Congestion of Nasolacrimal Duct
Congenital nasolacrimal duct obstruction (CNLDO) occurs in approximately 10 to 20% of all term newborns, and is the most common cause of persistent tearing and ocular discharge in children.
- Conditions
- Congenita Nasolacrimal Duct Obstruction, Preterm Neonates, Ocular Discharge
- Trial name
- Euphrasia (NCT04122300)
- Testing
- Euphrasia Officinalis Preparation
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- University of Bern
Unipolar Depression, Anxiety Disorder
Improve: Integrating Emotion Focused Components Into Psychological Therapy
The primary purpose of this study is to compare the efficacy of two treatment-as-usual (TAU) conditions: TAU with integration of emotion focused components (EFT) and TAU with focus on self-regulation (SR).
- Conditions
- Unipolar Depression, Anxiety Disorder, Adjustment Disorder
- Trial name
- Improve (NCT02822443)
- Testing
- Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT), Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR)
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- University of Bern
Cervical Cancer
Human Papillomavirus in Cervical Cancer and Pre-cancer in Switzerland: The CIN3+Plus Study
This study will investigate the types of HPV in samples from women with cervical pre-cancer and cancer and gather information to help investigate the impact of HPV vaccination in Switzerland.
- Trial name
- CIN3+plus (NCT02323997)
- Where
- 10 sites in Switzerland
- Volunteers
- 767 people
- Sponsor
- University of Bern
Gonorrhoea
Rapid Diagnosis of Antibiotic Resistance in Gonorrhoea
The purpose of this study is to develop a laboratory-based assay that will be a real-time PCR test to detect the organism N. gonorrhoeae and its most important genetic markers of antimicrobial resistance.
- Trial name
- RaDAR-Go (NCT02350907)
- Where
- 3 sites in Switzerland
- Volunteers
- 261 people
- Sponsor
- University of Bern
Colorectal Cancer
Colorectal Cancer Screening Among Primary Care Physicians of the Swiss Sentinel Surveillance Network
Colorectal cancer (CRC) is the third leading cause of cancer mortality in Switzerland, and kills 1600 people annually. Most deaths could be prevented by screening, but the 2012 Swiss national health survey found that only 40% of…
- Trial name
- NCT03552744
- Testing
- Mailed training intervention
- Where
- Switzerland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bern
Schizophrenia, Hallucinations
Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Schizophrenia is a severe mental disorder which is accompanied by an enormous individual and societal burden. Despite established efficacy of cognitive behavioral therapy for psychosis (CBTp), its dissemination into routine…
- Conditions
- Schizophrenia, Hallucinations, Persecutory Delusion
- Trial name
- EviBaS (NCT02974400)
- Testing
- Internet-based, CBT-oriented, guided self-help
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 101 people
- Sponsor
- University of Bern
Schizophrenia and Related Disorders
Transcranial Magnetic Stimulation to Improve Gesture Control
The majority of schizophrenia patients is impaired in hand gesture performance, which contributes to poor functional outcome and poor communication skills.
- Trial name
- GestTMS (NCT03483909)
- Testing
- left IFG iTBS, right IPL cTBS
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Trauma, PTSD
Posttraumatic Stress Symptoms Among Rescuers at Risk
This cross-sectional, anonymous online survey aims to examine how salient variables influence PTSS, well-being, and suicidal ideation across the following professions of rescue workers: firefighters, ambulance personnel, police…
- Conditions
- Trauma, PTSD, Self Efficacy, Coping Skills
- Trial name
- NCT03842553
- Testing
- No Intervention: anonymous online survey
- Where
- Switzerland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alveolar Ridge Augmentation
Lateral Ridge Augmentation Using Allograft Blocks and GBR for Implant Sites
Clinicians are increasingly faced with the challenge of reconstructing the alveolar ridge as more patients desire fixed implant-supported restorations.
- Trial name
- NCT03879967
- Testing
- Allograft block graft
- Where
- Switzerland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Bern
Bulimia Nervosa, Eating Disorders
Neural Response to Catecholamine Depletion in Subjects Suffering From Bulimia Nervosa in Their Past and Healthy Controls
Bulimia nervosa is a severe psychiatric disorder characterized by recurrent binge eating episodes followed by inappropriate compensatory behavior to prevent weight gain such as self-induced vomiting.
- Conditions
- Bulimia Nervosa, Eating Disorders, Dopamine, Reward
- Trial name
- NCT02179814
- Testing
- AMPT/ Demser, Diphenhydramine
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bern
Insomnia
i-Sleep: Internet-based Treatment for Insomnia
In this study, people who suffer from insomnia will be randomized to one of three study conditions. The first group receives a multicomponent internet-based cognitive behavioral self-help intervention.
- Trial name
- i-Sleep (NCT03110263)
- Testing
- Multicomponent internet-based self-help, Internet-based sleep restriction
- Where
- Switzerland
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Bern
Prolonged Grief Symptoms
Internet-based Self-help After Spousal Bereavement or Divorce
The purpose of this study is to evaluate the efficacy of an internet-based self-help intervention for older adults with prolonged grief symptoms after spousal bereavement or separation/divorce.
- Trial name
- LIVIA (NCT02900534)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Bern
Stroke
Replacing Canes With an Elasticated Orthosis in Chronic Stroke Patients: The Influence on Gait and Balance. A Series of N-of-1 Trials
This study aims to investigate the effect of an elasticated orthotic garment "Thera Togs" on walking ability and balance in currently cane using chronic stroke subjects (minimum 6 months post stroke) using a series of N-of-1…
- Trial name
- NCT03642444
- Testing
- Cane, Elasticated worn orthotic-garment
- Volunteers
- 4 people
- Sponsor
- Technical University of Bern
Dental Trauma, Avulsion
Effect of Topical Tetracycline and Dexamethasone on Periodontal and Pulpal Regeneration of Replanted Avulsed Teeth
To evaluate the effect of topical tetracycline and dexamethasone on periodontal and pulpal regeneration of avulsed permanent teeth after an observation period between 9-16 years.
- Conditions
- Dental Trauma, Avulsion, Periodontal Regeneration, Pulpal Regeneration
- Trial name
- NCT03611920
- Testing
- Tetracycline, Dexamethasone
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- University of Bern
Stomal Bleeding, Stomatitis, Denture
Clinical Trial for Evaluating Sage-Based Mouthrinse
The investigators aim to evaluate a sage-based mouthrinse (Dr. Hauschka Med, Mundspülung Salbei) whether it is less or equal effective in alleviating inflammatory signs of intra-oral mucosa and gingiva than an water/alcohol-based…
- Conditions
- Stomal Bleeding, Stomatitis, Denture, Tooth Staining, Satisfaction
- Trial name
- NCT02830802
- Testing
- Dr. Hauschka Med Mundspüllösung Salbei / cosmetics
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Fibrous Hyperplasia on Oral Mucosa
Comparison of ER:YAG Laser, CO2 Laser and Scalpel Excision of Fibrous Hyperplasia on the Buccal Mucosa
The aim of the RCT is to analyse clinical and histopathological particularities for excisional biopsies of fibrous hyperplasia in the buccal mucosa performed with Er:YAG laser, CO2 laser and scalpel.
- Trial name
- NCT03001791
- Testing
- Excisional biopsy with Er:YAG laser, Excisional biopsy with CO2 laser, Excisional biopsy with scalpel
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Bern