Clinical trials: sponsored by University of British Columbia
Bacterial Vaginosis
BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Study
Bacterial vaginosis (BV), the world's most common vaginal infection, continues to cost patients time, energy, comfort and money.
- Trial name
- NCT00799214
- Testing
- Boric acid, Metronidazole
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Altitude Sickness, Hypertension, Pulmonary
AZ, MZ, and the Pulmonary System Response to Hypoxia
The purpose of this proposal is to compare the physiological effects of acetazolamide (AZ) and methazolamide (MZ) on the control of breathing and hypoxic pulmonary vasoconstriction.
- Trial name
- NCT02760121
- Testing
- Acetazolamide, Methazolamide
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung; Disease, Interstitial, With Fibrosis
Mechanisms of Exertional Dyspnea in Fibrotic Interstitial Lung Disease
Exertional dyspnea is a major source of crippling distress and is the hallmark symptom of fibrotic interstitial lung disease (ILD).
- Trial name
- Dyspnea_ILD (NCT01781793)
- Testing
- Room air, Hyperoxia
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Cystic Fibrosis, Bronchiectasis
Adherence to Airway Clearance. Novel Approaches to Improving Adherence
An airway clearance technique (ACT) is one of the core treatments for children with chronic lung diseases who are unable to clear their secretions effectively.
- Trial name
- NCT02906826
- Testing
- Video game
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Chronic Obstructive Pulmonary Disease
The Effects of Aerobic Exercise Training on Vascular, Cardiac and Cerebral Vascular Function in COPD
The primary cause of chronic obstructive pulmonary disease is smoking, which can lead to inflammation in the lungs and blood vessels that can lead to secondary problems such as blood vessel disease, high blood pressure and heart…
- Trial name
- NCT02875522
- Testing
- Individualized, non-linear aerobic exercise training
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Neoplasms, Neoplasms by Site
The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction
Breast reconstruction is a common procedure with over 86,000 breast reconstruction procedures performed in the United States in 2009. This is a 1.5-fold increase since 2007.
- Conditions
- Breast Neoplasms, Neoplasms by Site, Neoplasms, Breast Diseases
- Trial name
- Botox (NCT01427400)
- Testing
- Botulinum Toxin-A, Saline
- Where
- 2 sites in Canada
- Volunteers
- 128 people
- Sponsor
- University of British Columbia
Diabetes Mellitus Type 2
Online Support for Diabetes Self-Management
The purpose of this study is to evaluate the effect of online support for diabetes self-management for patients with Type II diabetes in the Vancouver region.
- Trial name
- NCT02504086
- Testing
- Online Support
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of British Columbia
Gastrointestinal Hemorrhage, Crohn Disease
Prucalopride Prior to Small Bowel Capsule Endoscopy
Small bowel capsule endoscopy is a test used to investigate for any abnormalities in the small bowel. The small bowel is about 4 meters long. The battery time of the capsule is about 8 hours.
- Conditions
- Gastrointestinal Hemorrhage, Crohn Disease, Celiac Disease, Intestinal Diseases
- Trial name
- NCT02806206
- Testing
- Prucalopride
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- University of British Columbia
Periodontal Disease, Tissue Adhesive
The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound Healing
Periodontal disease is a gum infection caused by plaque on teeth containing both bacteria and calculus (hard) deposits. These need to be removed on a regular basis to maintain gum health and to prevent teeth weakening.
- Conditions
- Periodontal Disease, Tissue Adhesive, Dental Scaling, Wound Healing
- Trial name
- NCT02826109
- Testing
- PeriAcryl®90 HV
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients
Osteoarthritis (OA) is the most common joint disease associated with aging. Although many patients take glucosamine supplements as a non-traditional treatment for osteoarthritis, the effectiveness of these supplements is…
- Trial name
- NCT01074476
- Testing
- Glucosamine sulphate
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Colonoscopy
2L Oral Bi-PegLyte Versus 2L Oral MoviPrep Regimen for Outpatient Colonic Preparation
This study is a randomized, controlled, single centre, endoscopist-blinded non-inferiority trial. The purpose of our study is to determine if using a 2-litre mixture in combination with vitamin C is better than using 2 litres of…
- Trial name
- NCT01865916
- Testing
- Polyethylene Glycol (PEG) and 15 mg Bisacodyl, Polyethylene Glycol (PEG) + ascorbic acid
- Where
- Canada
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Fracture
Diffusion MRI and Growth Plate Injuries: Pilot Study
Children who suffer fractures to the growth plates (physes) of their bones are at risk for premature growth arrest which can lead to long term complications.
- Trial name
- NCT01774539
- Testing
- Diffusion MRI
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Shoe Orthotics for Improvement of Biomechanics and Symptoms of Knee Osteoarthritis
Knee osteoarthritis (OA) is a widespread problem in Canada, leading to decreased quality of life and increased economic burden. Current research has focused on expensive, invasive treatments, whereas inexpensive conservative…
- Trial name
- NCT02234895
- Testing
- Lateral wedge, Lateral wedge plus medial arch support
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Randomized Controlled Trial of Dynamic Balance Training in People With Knee Osteoarthritis
There is a high prevalence of falls in those with knee osteoarthritis (OA) compared to healthy older adults. Balance is a key element of function that allows individuals to maintain posture and respond to perturbations, and poor…
- Trial name
- NCT02103907
- Testing
- Targeted dynamic balance training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Breast Cancer
Can Exercise Improve Cancer Associated Cognitive Dysfunction?
Following chemotherapy, some breast cancer survivors report alterations in their ability to remember, concentrate, or think, which can have significant emotional, psychological, and economic impact on their lives.
- Trial name
- chemobrain (NCT01296893)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of British Columbia
Opioid Dependence, Heroin Dependence
Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)
The purpose of this study, SALOME, is to determine if 1) the closely supervised provision of injectable, hydromorphone (HDM; trade name Dilaudid™) is as effective as injectable diacetylmorphine (DAM; heroin) in the treatment of…
- Trial name
- SALOME (NCT01447212)
- Testing
- Hydromorphone, Injectable, Diacetylmorphine, injectable, Hydromorphone, liquid oral
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- University of British Columbia
Gender Dysphoria
Subcutaneous Testosterone Project
For people who identify as transgender, there is a strong sense that they were born into the wrong body and that their outward looking body does not match how they truly feel about themselves.
- Trial name
- STP (NCT02229617)
- Testing
- Subcutaneous testosterone
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Urinary Tract Infection
Cranberry for the Prevention of Urinary Tract Infections
This study aims to determine whether a cranberry concentrate reduces recurrent urinary tract infections (UTIs) in women. Approximately 150 adult women will be recruited to participate in this study.
- Trial name
- NCT02454309
- Testing
- Cranberry concentrate
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Urinary Incontinence
Treatment of Persistent Urinary Incontinence in Children
The purpose of this study is to determine whether surgical section of the filum terminale in children, when added to standard medical therapy, will result in a reliable and clinically-significant improvement in two main markers…
- Trial name
- NCT00124046
- Testing
- Surgery, Medical Treatment
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia