Clinical trials: sponsored by University of Calgary
POTS
POTS Stroke Volume
the investigators propose studies of a tiny, wearable, wireless, beat-to-beat blood pressure monitor that will be both a transformative research platform and an enabler of patient self-care in the diagnosis, investigation, and…
- Trial name
- NCT05796154
- Testing
- ear blood pressure monitor
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Syncope
Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial
The Study To Understand Tilt Tests versus Extended Recordings (STUTTER, POST 10) will test the hypothesis that first performing a diagnostic HUT in older patients with syncope of unknown cause will provide earlier and more…
- Trial name
- (POST10) (NCT05776810)
- Testing
- Diagnostic Test: Head Up Tilt Table (HUT), Device: Implantable Loop Recorder
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- University of Calgary
Ehlers-Danlos Syndrome, Anesthesia, Local
Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers
Local anesthetic resistance is commonly reported by patients with EDS. However, there are no objective data on the occurrence of local anesthetic resistance in EDS patients and in healthy volunteers.
- Trial name
- NCT05603741
- Testing
- 0.9% Sodium Chloride Injection, Lidocaine Injection 2%
- Where
- Canada
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Neuropathic Pain
Treatment of Neuropathic Pain Following Spinal Cord Injury - a RTMS Approach
This study aims to determine if repetitive transcranial magnetic stimulation (rTMS) can improve pain symptomology in adults with neuropathic pain (NP) following a spinal cord injury (SCI).
- Trial name
- NCT06284694
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Diet, Healthy, Health Risk Behaviors
Impact of BC Farmers' Market Nutrition Coupon Program on Diet Quality and Psychosocial Well-being of Low-income Adults
The British Columbia (BC) Farmers' Market Nutrition Coupon Program (FMNCP) provides low-income households with $21/week in coupons to purchase healthy foods at farmers' markets and supportive nutrition skill-building activities.
- Trial name
- NCT03952338
- Testing
- Food coupons, Nutrition skill-building
- Where
- Canada
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Premature Birth
A Cluster Randomized Controlled Trial of FICare At 18 Months
In Alberta, one in every twelve babies is born preterm. Compared with their full term counterparts, preterm infants who survive are at higher risk for respiratory problems, jaundice, infections, feeding problems, behavioural…
- Trial name
- NCT03337659
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 297 people
- Sponsor
- University of Calgary
Juvenile Idiopathic Arthritis
Virtual Self-Management Program for JIA
The aim of this project is to conduct a pilot randomized controlled trial (RCT) to evaluate the feasibility and preliminary effectiveness of a virtual group based self-management program (SMP) in adolescents with JIA across…
- Trial name
- NCT06184100
- Testing
- Virtual Self-Management Program (SMP), No Intervention
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Osteo Arthritis Knee, Obesity
Effect of Prebiotics on Function and Pain in Patients with Osteoarthritis and Obesity
The purpose of the present study is to determine if prebiotic supplementation can, through changes in the intestinal gut microbiota, lead to improvements in knee function and physical performance and reduce knee pain in adults…
- Trial name
- NCT04172688
- Testing
- Prebiotic oligofructose-enriched inulin
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Atrial Fibrillation, Obesity
Behavioural Weight Loss Treatment for Patients with Atrial Fibrillation and Obesity in Cardiac Rehabilitation
One-in-four Canadians will be diagnosed with an abnormal heart rhythm called atrial fibrillation (AF) in their lifetime. People with AF have an increased chance of having serious medical problems like stroke and heart failure.
- Trial name
- BE-WEL in CR (NCT05230823)
- Testing
- CR with added BWLT
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Calgary
Insomnia, Sleep Disturbance
Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk
Emerging evidence has shown that sleep interventions such as Cognitive Behavioral Therapy for Insomnia (CBT-I) improve depressive and anxiety symptoms in adults, even when the intervention is brief, such as four to six sessions.
- Conditions
- Insomnia, Sleep Disturbance, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT06358495
- Testing
- Cognitive Behavioral Therapy for Insomnia, Active Control
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Recurrent or Progressive Diffuse Intrinsic Pontine Glioma
Re-Irradiation of Progressive or Recurrent DIPG
This is a single-arm, non-randomized study of re-irradiation of diffuse intrinsic pontine glioma (DIPG)
- Trial name
- NCT03126266
- Testing
- re-irradiation
- Where
- 18 sites in Australia, Canada and 1 more
- Volunteers
- 27 people
- Sponsor
- University of Calgary
Peripheral Pulmonary Lesions, Lung Cancer
Peripheral EBUS With ROSE vs no ROSE; Slim Bronchoscope Without Guide Sheath vs Standard Bronchoscope With Guide Sheath
Peripheral pulmonary lesions (PPL) are defined as nodules or masses that are located in the lung periphery; hence cannot be seen via regular bronchoscopy.
- Trial name
- NCT03809169
- Testing
- Rapid on-site evaluation (ROSE), Slim bronchoscope without a guide sheath, Standard pEBUS with guide sheath
- Where
- 2 sites in Canada
- Volunteers
- 186 people
- Sponsor
- University of Calgary
Bone Loss, Bone Loss, Age-related
Strength Training for Osteoporosis Prevention During Early Menopause
The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females.
- Conditions
- Bone Loss, Bone Loss, Age-related, Osteoporosis, Musculoskeletal Diseases
- Trial name
- STOP-EM (NCT05961371)
- Testing
- Resistance Training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Violence, Gender-Based
Evaluation of the WiseGuyz Program for Adolescent Boys
Adolescent dating violence (ADV) is a pressing public health problem in North America, and strategies to prevent perpetration are needed.
- Trial name
- NCT03994016
- Testing
- WiseGuyz
- Where
- Canada
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Breast Cancer, Medication Adherence
Motivational Enhancement Therapy to Improve Adherence to Aromatase Inhibitors
The proposed research is a randomized controlled investigation of the efficacy of motivational interviewing (MI) to improve adherence to aromatase inhibitors (AI) in a community sample of patients with poor adherence to AIs.
- Trial name
- MI for AIs (NCT02883361)
- Testing
- Motivational enhancement therapy, Attention Control
- Where
- Canada
- Sponsor
- University of Calgary
Malaria, Pregnancy Malaria
LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial
Objective: The aim of this study is to evaluate the impact of enhanced malaria cases detection using molecular testing (LAMP) on maternal and infant morbidity and mortality in a prospective study design.
- Conditions
- Malaria, Pregnancy Malaria, Malaria in Pregnancy
- Trial name
- LAMPREG (NCT03754322)
- Testing
- LAMP, Microscopy/RDT
- Where
- 4 sites in Canada, Ethiopia
- Volunteers
- 2,424 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Suicidal Ideation, Suicide, Attempted
iTBS+D-Cycloserine for Youth Suicide
Background and Rationale: Suicide is the second leading cause of death in Canadian Emerging Adults (EAs; 18-24yrs). Current treatments for suicidal thoughts and behaviors are limited and novel treatments are required to save…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Depression, Anxiety
- Trial name
- NCT06121284
- Testing
- D-Cycloserine, intermittent Theta-Burst-repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Congenital Heart Disease (CHD)
Feasibility of a Virtual Mental Health Intervention for Children with Congenital Heart Disease
Children with congenital heart disease are at much higher risk for behavioral and emotional difficulties in early childhood and beyond 1.
- Trial name
- NCT06659302
- Testing
- I-inTERACT North Step 1, I-inTERACT North step 2, I-inTERACT North
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Autoimmune Rheumatologic Disease
Hepatitis A Vaccine Dosing Regimens Among Pediatric Patients on Immunosuppressive Therapy
The study is a prospective, single centre, double-blinded randomized controlled trial whose goal is to compare the immune response of a population of immunosuppressed pediatric rheumatology patients on immunosuppressive…
- Trial name
- NCT02917577
- Testing
- Avaxim Pediatric®, Avaxim ® (adult)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Calgary