Clinical trials: sponsored by University of Calgary
Cancer-related Fatigue
Tailored Exercise Interventions to Reduce Fatigue in Cancer Survivors
Cancer-related fatigue (CRF) is a common and distressing symptom of cancer and/or cancer treatment that can persist for months or years in cancer survivors.
- Trial name
- NCT03049384
- Testing
- Traditional Exercise, Tailored Exercise
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Calgary
Concussion, Mild, Diagnoses, Syndromes, and Conditions
Diagnosis of Sport-related Concussion Using Urine Metabolites
Millions of sport related concussions (SRC) occur yearly in the United States, and current diagnosis of concussion is based upon largely subjective clinical evaluations.
- Trial name
- NCT03653195
- Testing
- urine metabolomics
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Cancer
Living With Colorectal Cancer: Patient and Caregiver Experience
This observational study will gather outcome and experience data of patients living with advanced colorectal cancer and their caregivers.
- Trial name
- NCT03572101
- Where
- 3 sites in Canada
- Volunteers
- 280 people
- Sponsor
- University of Calgary
Sternal Closure
Montage-Enhanced Sternal Closure
Post-operative recovery after cardiac surgery is influenced by early sternal bone stability. Traditional sternal closure of median sternotomy usually entails the use of 6-10 stainless steel wires.
- Trial name
- NCT03365843
- Testing
- Montage bone putty, Conventional Sternal Closure
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Calgary
Concussion, Brain, Traumatic Injury
Sport Concussion Performance-Based Prevention Program
Sport-related concussions and traumatic lower body injuries (e.g., anterior cruciate ligament (ACL) tears) occur frequently in high-speed and contact/collision sports contributing to significant time loss from…
- Trial name
- NCT04992130
- Testing
- Pre-season supplementary neurologic training program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Crohn Disease, Ulcerative Colitis
Digital Nutrition Therapy for Patients With IBD
Background: Alberta's Center of Excellence for Nutrition in Digestive Diseases (Ascend) is dedicated to generating new discoveries regarding the link between nutrition and digestive diseases and mobilizing existing research to…
- Trial name
- LYFEMD (NCT04653259)
- Testing
- LYFE MD app
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Psychotic Disorders
Brain Effects of Memory Training in Early Psychosis
Background: People with psychosis show profound deficits in memory. A new cognitive remediation therapy using an app on a computer or mobile phone to improve memory has been effective in this population, but the neurobiological…
- Trial name
- NCT02584114
- Testing
- Peak app for memory training, Non-memory training group
- Volunteers
- 14 people
- Sponsor
- University of Calgary
Multiple Sclerosis, Primary Progressive
Hydroxychloroquine in Primary Progressive Multiple Sclerosis
The purpose of this clinical trial is to determine if HCQ in a dose of 400mg daily can prevent worsening of walking ability in people PPMS. The number of participants in this study will be 35.
- Trial name
- NCT02913157
- Testing
- Hydroxychloroquine
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Rotator Cuff Tears
Superior Capsule vs Bridging Study
Randomized controlled trial examining superior capsule reconstruction versus tendon repair with graft interposition in "irreparable" rotator cuff tears.
- Trial name
- SCR (NCT04965103)
- Testing
- SCR, Bridging
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Knee Osteoarthritis
Mindfulness Meditation for Surgical Pain and Anxiety
Health care professionals are dedicated to the ongoing evaluation of the peri-operative experience, and always striving to improve patient satisfaction.
- Trial name
- NCT04932499
- Testing
- Standard of Care, Mindfulness Meditation
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary
BPPV, Vertigo, Peripheral
Virtual Reality Epley Maneuver System (VREMS) for Treatment of Benign Paroxysmal Positional Vertigo
Background and Rationale: Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo, affecting 2.4% of the general population and 30% of those over 70 years old.
- Trial name
- NCT04436783
- Testing
- Virtual Reality Epley Maneuver System (VREMS), Instructional Handout (IH)
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Iron Deficiency Anemia, Abnormal Uterine Bleeding
Tolerability of Iron Therapy in Women With AUB
Telephone surveys of female patients using liposomally-bound iron and traditional iron sulphate preparations for the management of iron deficiency anemia to determine gastrointestinal tolerability.
- Trial name
- NCT04915196
- Testing
- Liposomally-bound Iron
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Pelvic Organ Prolapse
Hysterectomy Versus Uterine Preservation for Pelvic Organ Prolapse Surgery
Pelvic organ prolapse (POP) is the descent of pelvic organs into the vagina resulting in bulge symptoms and occurs in approximately 50% of women. Almost 20% of women will elect surgical correction of this condition by age 85.
- Trial name
- HUPPS (NCT04890951)
- Testing
- Hysteropexy, Hysterectomy and vaginal vault suspension
- Where
- Canada
- Volunteers
- 321 people
- Sponsor
- University of Calgary
Fissure in Ano, Rectal Diseases
Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure
Anal fissure is a common anorectal diseases characterized by tear of the anoderm from the dentate line to the anal verge leading to pain and bleeding during and post defecation.
- Conditions
- Fissure in Ano, Rectal Diseases, Rectal Bleed
- Trial name
- NCT04887818
- Testing
- 2% Diltiazem ointment with 1.5% lidocaine, 0.3% Nifedipine ointment with 1.5% lidocaine
- Where
- Canada
- Volunteers
- 430 people
- Sponsor
- University of Calgary
Depression
The Impact of Disclosing Personalized Depression Risk Information on High-risk Individuals' Outcomes
Major depressive episode (MDE) is one of the most prevalent and disabling form of mental illness in the general population. Despite increased mental health services and antidepressants use in the past 10 years, there has been no…
- Trial name
- NCT02943876
- Testing
- personalized depression risk information
- Where
- 2 sites in Canada
- Volunteers
- 712 people
- Sponsor
- University of Calgary
Prehabilitation, Colorectal Surgery
Pragmatic Prehabilitation for Colorectal Surgery
Colorectal surgery is a common surgery for the treatment of colon and rectal cancers as well as other bowel diseases. Recovery from colorectal surgery is difficult because of the many potential negative side effects.
- Conditions
- Prehabilitation, Colorectal Surgery, Enhanced Recovery After Surgery
- Trial name
- NCT04247776
- Testing
- Prehab, ERAS, Fitbit
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Calgary
Psychology, Pain
Reframe the Pain: A Parent-Led Intervention to Alter Children's Memories for Pain
Pain is a common experience in youth and influences youth long after the painful situations are over. Youth memory of pain after surgery can affect painful experiences in the future.
- Conditions
- Psychology, Pain, Stress, Behavior
- Trial name
- NCT03110367
- Testing
- Pain Reframing Intervention, Attention Control Group
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bone Lesion, Bone Metastases
Ablation and Cementoplasty for Painful Bone Lesions
The aim of this research study is to assess the effectiveness of combined ablation and cementoplasty in the treatment of spinal, pelvic, and extraspinal lesions causing pain resistant to conventional treatment at our centre.
- Conditions
- Bone Lesion, Bone Metastases, Spine Metastases
- Trial name
- NCT04635137
- Testing
- Ablation and Cementoplasty
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
End Stage Heart Failure
Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation
Continuous-flow left ventricular assist devices (LVAD) move blood from the left ventricle (the largest chamber of the heart) to the aorta (the body's main artery) to help the heart better meet the needs of the body and to improve…
- Trial name
- NCT03356353
- Testing
- Sildenafil Citrate
- Where
- 4 sites in Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Renal Dialysis, Fatigue
Pilot Study of an Educational Program for Adults on Hemodialysis With Fatigue
Fatigue is a common and problematic symptom of end-stage renal disease (ESRD). The investigators have developed a new program, called the Personal Energy Planning (PEP) program, that teaches people with ESRD to manage fatigue by…
- Conditions
- Renal Dialysis, Fatigue, Rehabilitation, Quality of Life
- Trial name
- Fatigue-HD (NCT03825770)
- Testing
- The "PEP" (Personal Energy Planning) Program, General Education about Kidney Disease
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Calgary