Clinical trials: sponsored by University of Calgary
Hemolytic-Uremic Syndrome
Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion
This study will provide feasibility data regarding the conduct of a clinical trail evaluating the use of early aggressive inpatient intravenous rehydration in children with Shiga Toxin producing E. coli infection.
- Trial name
- NCT03275792
- Testing
- D5-0.9%NS, Routine home oral rehydration
- Where
- Canada
- Sponsor
- University of Calgary
Migraine
Evaluation of an Aerobic Exercise Program in Migraine Management
This trial assesses the impact of a supervised aerobic exercise program by a kinesiologist in patients with migraine. Patients can be assigned to one of two groups 1)The exercise group or 2)non-exercise group.
- Trial name
- NCT01857557
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parkinson's Disease, Mild Cognitive Impairment
Longitudinal Study of Mild Cognitive Impairment in Parkinson's Disease
Parkinson's disease (PD) is known for its motor symptoms and affects more than 100,000 Canadians. However, PD patients also show cognitive deficits and neuropsychiatric problems that significantly impair their quality of life.
- Trial name
- PD-MCI (NCT02637089)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Tourette Syndrome
Transcranial Magnetic Stimulation for Children With Tourette's Syndrome
Tics are the core symptom of Tourette syndrome. These are repetitive, sudden, semi-voluntary movements or sounds. In some children, these tics can be especially bad and require treatment, however, options are limited.
- Trial name
- TICS (NCT02356003)
- Testing
- Low frequency repetitive transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Crohn Disease
Modeling Patient Response to a Therapeutic Diet in Crohn's Disease
BACKGROUND: There is an urgent need to understand the role of therapeutic dietary interventions on the treatment of inflammatory bowel disease (IBD).
- Trial name
- TDI (NCT04596566)
- Testing
- Therapeutic diet Intervention
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary
Parkinson's Disease, Mild Cognitive Impairment
Effect of Transcranial Magnetic Stimulation on Cognition and Neural Changes in Parkinson's Disease
Parkinson's disease (PD) affects more than 100,000 Canadians and results in symptoms affecting both motor and cognitive (thinking and memory) functions.
- Trial name
- PD-MCI-TMS (NCT03243214)
- Testing
- TMS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of Calgary
Gastroparesis, Diabetes Mellitus
Prucalopride Versus Placebo in Gastroparesis
The incidence of gastroparesis has been increasing among Canadians. Symptoms of discomfort include early satiety, stomach pain, nausea and vomiting.
- Trial name
- NCT02031081
- Testing
- Prucalopride
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Calgary
Major Depressive Disorder
Transcranial Magnetic Stimulation for Adolescent Depression
Major depression (or MDD) in adolescents is a major public health problem. MDD affects approximately 15% of adolescents; it is associated with impairment in social, family, and academic functioning, and it is a major risk factor…
- Trial name
- TMSAD (NCT01731678)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Essential Tremor
Alternating Current Stimulation for Essential Tremor
Movement disorders are common neurological disorders, characterized by either excess or paucity of movements. Essential tremor (ET) is one of the most common of these disorders, defined as chronic, rhythmic involuntary movements…
- Trial name
- NCT04509349
- Testing
- transcranial Altering Current Stimulation
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Heart Failure, Hyponatremia
Tolvaptan for Advanced or Refractory Heart Failure
This study will clarify the clinical usefulness of Tolvaptan therapy in patients with complicated acute decompensated heart failure and hyponatremia (low blood sodium).
- Trial name
- NCT02959411
- Testing
- Tolvaptan, Standard of care diuretic therapy
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Calgary
Covid19, COVID-19
Tocilizumab in Coronavirus-19 Positive Patients
This is a cohort study of COVID-19 patients with hyperinflammation. It aims to determine the impact of adjunctive Tocilizumab (TCZ) to standard of care on the reduction of hyperinflammation-related mortality in COVID-19.
- Conditions
- Covid19, COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2, Coronavirus
- Trial name
- NCT04423042
- Testing
- Tocilizumab
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome and Exercise
Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder characterized by oligo-ovulatory menstrual dysfunction, androgen excess and polycystic ovaries.
- Trial name
- NCT03362918
- Testing
- High Intensity Interval Training, Continuous Aerobic Exercise Training
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Maternal Death, Newborn Death
Replicating MamaToto in Rural Tanzania
This study aimed to adapt and implement a district-led, policy-based, low cost Maternal and Newborn Health (MNH) intervention package using the MamaToto process, proven successful in Uganda, in rural Tanzania.
- Trial name
- NCT02506413
- Testing
- MamaToto Package
- Where
- Tanzania
- Volunteers
- 8,323 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cesarean Section
Gastric Voume Assessment for Aspiration Risk in OB ERAS Patients
In recent years, human and animal studies have found that carbohydrate-loading prior to surgery leads to improved response to surgical stress and improved postoperative well-being when compared to traditional fasting guidelines.
- Trial name
- NCT03842527
- Testing
- Ultrasound
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary
Chronic Subdural Hematoma
Mgt of Chronic Subdural Hematoma Using Dexamethasone
Chronic subdural hematoma (cSDH) is a collection of blood and its breakdown products in the subdural compartment. It is a condition frequently seen in any neurosurgical practice.
- Trial name
- NCT02938468
- Testing
- Dexamethasone, Any surgical intervention aim at treating chronic subdural hematoma
- Where
- Canada
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Calgary
HIV Associated Neurocognitive Disorder (HAND)
Intranasal Treatment of HIV-associated Neurocognitive Disorders
This study aims to see whether intranasal insulin is an effective treatment for problems with memory, concentration, slowed thinking, or any other cognitive function in people living with HIV/AIDS.
- Trial name
- NCT03277222
- Testing
- IN insulin
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Calgary
ALS, Amyotrophic Lateral Sclerosis
A Clinical Trial of Pimozide in Patients With Amyotrophic Lateral Sclerosis (ALS)
This study will look at whether Pimozide may help to slow the progression of Amyotrophic Lateral Sclerosis. 100 people from several Canadian centres with ALS who have provided their consent will be randomly assigned into one of 2…
- Trial name
- Pimozide2 (NCT03272503)
- Testing
- Pimozide 2mg/day (current) or 4 mg/day (study initiation)
- Where
- 9 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Colorectal Neoplasms
Effectiveness of Endocuff Vision in Improving ADR
The goal of distal attachment devices is to enhance an endoscopist's adenoma detection rate (ADR). A device called EndoCuff Vision (ECV) has been introduced that employs a single row of flexible arms to evert colonic folds, thus…
- Trial name
- NCT04395352
- Testing
- Endocuff Vision (ECV)
- Where
- Canada
- Volunteers
- 15,816 people
- Sponsor
- University of Calgary
Knee Osteoarthritis, Total Knee Arthroplasty
A PROMs Based Educational Tool (PROM-DA) for Patients Considering Total Knee Arthroplasty
The primary objectives of this study are to: 1) develop an educational tool known as the Patient Reported Outcome Measure informed Decision Aid (PROM-DA) that will describe the options for patients considering total knee…
- Trial name
- NCT03240913
- Testing
- Baseline and Follow-up Surveys, Patient Reported Outcome Measure informed Decision Aid, Pamphlet
- Where
- Canada
- Volunteers
- 163 people
- Sponsor
- University of Calgary
Preterm Infant
Preterm Infant Multicentre Growth Study
The purpose of this study is to improve health professionals understanding of preterm infant growth patterns, and to determine if early growth patterns predict risks of adverse metabolic and cognitive outcomes.
- Trial name
- PreMGS (NCT03064022)
- Testing
- Growth
- Where
- 2 sites in Canada
- Volunteers
- 1,275 people
- Sponsor
- University of Calgary