Clinical trials: sponsored by University of Calgary
Neurosurgery
Neurosurgical Skill Enhancement Using Transcranial Stimulation
Recent changes in medical training environments and restrictive work-hour regulations have greatly impacted trainees, limiting the number of opportunities to gain proficiency in procedural skills.
- Trial name
- LETS-LEARN (NCT02987816)
- Testing
- Anodal tDCS
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pelvic Girdle Pain
Biomechanical Effects of Wearing a Sacroiliac Belt in Women
Women with pelvic girdle pain PGP) often get relief from using a sacroiliac belt. The study will explore if there are differences and in the changes of lower body movement in stability with the belt on and with the belt off.
- Trial name
- NCT03334799
- Testing
- sacroiliac belt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Acute Coronary Syndrome, Heart Failure
Epicardial Infarct Repair Using CorMatrix®-ECM: Clinical Feasibility Study
Epicardial Infarct Repair with CorMatrix-Extracellular Matrix (ECM) is an open-label, non-randomized, feasibility pilot study. Following ischemic injury the ECM of the heart adversely remodels leading to cardiac fibrosis, left…
- Trial name
- EIR (NCT02887768)
- Testing
- Epicardial Infarct Repair with CorMatrix-ECM, Coronary Artery Bypass Grafting Surgery
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Calgary
Overweight, Obesity
Effect of Prebiotic Intake on Adiposity, Satiety and Gut Microbiota in Overweight and Obese Children
Currently, over one third of Canadian children and youth aged five to seventeen are overweight or obese. Childhood obesity leads to increased risks of co-morbidities such as type 2 diabetes, fatty liver disease, cardiovascular…
- Trial name
- NCT02125955
- Testing
- Prebiotic fiber
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Surgical Wound Infection, Pancreatic Neoplasms
The Use of Wound Protector in Whipple's Procedure With Intrabiliary Stent
Background: There are no published studies regarding the use of wound protectors in the context of surgical site infection (SSI) rates among patients receiving a pancreatoduodenectomy (Whipple) with preoperatively placed…
- Trial name
- NCT01836237
- Testing
- Alexis - a wound protector
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- University of Calgary
Obesity
Effect of Protein and Prebiotic Fiber Intake on Adiposity in Overweight and Obese Adults
The metabolic syndrome is rising worldwide as a consequence of the continued obesity epidemic. The current obesogenic environment makes the regulation of energy intake difficult and impedes the maintenance of weight loss.
- Trial name
- NCT02217579
- Testing
- Protein, Prebiotic fiber, Protein plus prebiotic fiber
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Non-Alcoholic Fatty Liver Disease
Histological Improvement of NASH With Prebiotic
This trial will investigate the therapeutic potential of a prebiotic supplement to improve histological parameters of NASH. In a single-blind, placebo controlled, randomized pilot trial will be conduced in individuals with liver…
- Trial name
- NCT03184376
- Testing
- Prebiotic oligofructose
- Volunteers
- 14 people
- Sponsor
- University of Calgary
Colorectal Disorders, Surgery
A Comparison of Protein Intake Between ERAS and Conventional Care After Elective Colorectal Surgery
The primary objective of this prospective cohort study is to compare protein intake and adequacy between patients receiving Enhanced Recovery After Surgery (ERAS) protocols with patients receiving conventional care.
- Trial name
- NCT02940665
- Testing
- ERAS
- Volunteers
- 115 people
- Sponsor
- University of Calgary
Post-concussion Syndrome, Post-concussive Symptoms
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
PURPOSE: The long-term goal of this line of research is to develop rational, biologically based evidence for the treatment of post-concussion syndrome (PCS) in children.
- Conditions
- Post-concussion Syndrome, Post-concussive Symptoms, Traumatic Brain Injury, Concussion
- Trial name
- PLAYGAME (NCT01874847)
- Testing
- Melatonin, Sugar pill
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression, Psychosis
Cognitive Remediation in Youth at Risk of Serious Mental Illness
The primary aim of the project is to test the effectiveness of a cognitive remediation treatment (CRT) program, My Brain Solutions (MBS), in addition to motivational interviewing (MI) in improving cognition and functional outcome…
- Conditions
- Depression, Psychosis, Anxiety, Mental Illness
- Trial name
- NCT02582528
- Testing
- Cognitive remediation treatment, Motivational Interviewing
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Arsenic Poisoning
High-selenium Lentils Versus Arsenic Toxicity
About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases.
- Trial name
- NCT02429921
- Testing
- high-selenium lentils, Low-Se lentils
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Premature Birth
Fathers and Late Preterm Babies Study
The purpose of this study is to test an educational intervention for first-time fathers of late preterm (34 to 36 weeks gestation) infants.
- Trial name
- FLPTB (NCT01056653)
- Testing
- Standard Dose, High Dose, Comparison Group
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- University of Calgary
Obesity, Overweight
Does Motivational Interviewing Improve Behavioral Weight Loss Outcomes for Obesity?
The purpose of this study is to determine whether adding motivational interviewing (MI) to a behavioural weight loss program (BWLP) results in improved weight loss for adults who are overweight or obese.
- Trial name
- BWLP+MI (NCT02649634)
- Testing
- Motivational Interviewing, Attention Control
- Volunteers
- 135 people
- Sponsor
- University of Calgary
Dupuytren Contracture, Dupuytren's Disease of Finger
Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's Disease
Dupuytren's disease is a non-curative, progressive disorder leading to function-impairing deformities of the hand. Although numerous treatments exist, the most common and widely accepted therapy is removal of diseased fascia.
- Trial name
- NCT03000114
- Testing
- Percutaneous Needle Aponeurotomy, XIAFLEX
- Where
- Canada
- Volunteers
- 334 people
- Sponsor
- University of Calgary
Wheeze
Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children
The investigators goal is to conduct a pilot randomized controlled trial (RCT) whose purpose is to determine the feasibility of a randomized trial designed to determine if either inhaled beclomethasone or a combination of inhaled…
- Trial name
- CONjuGATE (NCT02319564)
- Testing
- Beclomethasone, Beclomethasone and Salbutamol, Aerochamber Max®
- Where
- Canada
- Sponsor
- University of Calgary
Patellofemoral Pain Syndrome
Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is the most common overuse injury seen in the athletic population, particularly amongst runners. The standard of care treatment for PFPS is a comprehensive active rehabilitation program.
- Trial name
- NCT02613247
- Testing
- Hylan G-F 20
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Depression, Anxiety
Mental Health E-screening in Pregnant and Postpartum Women
To compare e-screening versus usual screening on: 1) women's and healthcare providers' views on feasibility and acceptability; 2) rates of detection of prenatal and postpartum depression and anxiety; 3) perceived risk and benefit…
- Trial name
- NCT01899534
- Testing
- E-screening
- Where
- 3 sites in Canada
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cancer of Head and Neck
Exercise and Nutrition for Head and Neck Cancer Patients
Research on physical activity and nutrition interventions aimed at positively impacting symptom management, treatment-related recovery and quality of life has largely excluded head and neck cancer populations.
- Trial name
- ENHANCE (NCT01681654)
- Testing
- Lifestyle Intervention, Maintenance Intervention
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Cancer, Autologous Hematopoietic Stem Cell Transplantation
Exercise in Pediatric Autologous Stem Cell Transplant Patients
Hematopoietic stem cell transplantation is an intensive therapy used to improve survivorship and cure various oncologic diseases. However, this therapy is associated with high mortality rates and numerous negative side-effects.
- Trial name
- SCORE (NCT01666015)
- Testing
- EXERCISE (EX), Standard Care
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Family Caregivers
Renewing Caregiver Health and Well-being Through Exercise
The RECHARGE study is evaluating the effect of a 24 week structured exercise and education program on the physical and emotion health, quality of life, physical activity and fitness levels of family caregivers.
- Trial name
- RECHARGE (NCT02580461)
- Testing
- A 24 week center-based structured exercise and education program
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Calgary