Clinical trials: sponsored by University of Calgary
Bone Marrow Failure Syndrome
The Impact of Red Cell Age on Product Utilization in the Chronically Transfused Outpatient Population
In this study, the investigators will be evaluating the impact of red blood cell age in patients receiving chronic blood transfusions in the outpatient setting.
- Trial name
- ABC-TOP (NCT02393508)
- Testing
- Fresh Human Red Blood Cells, Aged Human Red Blood Cells
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Acute Pain Following Decompressive Lumbar Spinal Surgery
The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery
The primary aim of this study is to assess the impact of intrathecal morphine on post-operative pain following instrumented fusion for degenerative lumbar spine disease.
- Trial name
- ITMP (NCT01053039)
- Testing
- Intrathecal Morphine, Intrathecal Saline
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Knee Osteoarthritis
Wedged Insoles for Management of Knee Osteoarthritis
Knee osteoarthritis (OA) is commonly treated using laterally wedged insoles. Although these insoles typically reduce knee abduction moments (KAM) - a variable associated with knee osteoarthritis - and thus are believed to be…
- Trial name
- NCT02067208
- Testing
- wedged insole
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Calgary
Crisis Resource Management
Can Adherence to PALS Guidelines be Improved by Team Training of Pediatric Resuscitation Members?
A multi-centre prospective cohort study, which examines the effect of a team training educational intervention for pediatric resuscitation team members.
- Trial name
- Teams4Kids (NCT02075645)
- Testing
- Team training course
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Coronary Artery Disease, Complication of Coronary Artery Bypass Graft
Negative Pressure Dressing After Saphenous Vein Harvest
This study will test the effectiveness of negative pressure wound therapy (using the VAC Prevena device, KCI Canada Inc.) applied to the saphenous vein harvest site after Coronary Artery Bypass Grafting (CABG).
- Conditions
- Coronary Artery Disease, Complication of Coronary Artery Bypass Graft, Wound Complication
- Trial name
- NCT01698372
- Testing
- Prevena device (Group A)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Heart Failure, Congestive, Cardiac Pacing, Artificial
Effect of Targeting Left Ventricular Lead Position on the Rate of Response to Cardiac Resynchronization Therapy.
Identifying \& optimizing strategies to reduce the burden of heart failure is vital. Despite advances in pharmacotherapy, patients with heart failure are at high risk for death \& hospitalization.
- Conditions
- Heart Failure, Congestive, Cardiac Pacing, Artificial, Defibrillators
- Trial name
- INCREMENTAL (NCT00399594)
- Testing
- A, B
- Where
- 3 sites in Canada
- Volunteers
- 96 people
- Sponsor
- University of Calgary
Heart Failure, Congestive
Torsion Optimization to Reduce Symptoms and Improve Outcomes in Non-responders
Approximately 40% of resynchronization therapy recipients do not appear to clearly benefit. These patients are termed 'non-responders'.
- Trial name
- TORSION (NCT00867984)
- Testing
- Torsion optimized, Usual Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Heart Failure
Optimal Programming to Improve Mechanical Indices, Symptoms and Exercise in Cardiac Resynchronization Therapy.
This international study is assessing if repeat adjustment of the timing between the three leads in a cardiac resynchronization therapy (CRT) defibrillator will increase the likelihood of benefit (symptoms and heart function)…
- Trial name
- OPTIMISE-CRT (NCT00489177)
- Testing
- A, B
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University of Calgary
Hepatitis C
Triple-Therapy in Patients With HCV Genotype 3 Who Previously Failed Treatment
The purpose of this study is to test the potential antiviral efficacy of triple-combination therapy with Peginterferon α-2b + ribavirin + boceprevir (PRB) in patients with HCV genotype 3 who previously failed Peginterferon α +…
- Trial name
- LeeG3 (NCT01585584)
- Testing
- Boceprevir
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Running, Leg Injuries
Exercise Interventions, Running Biomechanics and Injury in Novice Runners
The purpose of this study is to understand the effects of muscle strengthening and balance exercise interventions on muscle strength, running mechanics and postural control in novice recreational runners.
- Trial name
- NCT01900262
- Testing
- Strengthening, Balance Training, Stretching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Intradialytic Hypotension, End Stage Renal Failure on Dialysis
Adjusting Fluid Removal Based on Blood Volume in Hemodialysis: A Randomized Study
As kidney function declines, the ability to maintain water balance is impaired and is most often treated with hemodialysis. The removal of excess water in hemodialysis often leads to a sudden drop of blood pressure and causes…
- Trial name
- NCT01988181
- Testing
- BVM-UF biofeedback, Fresenius 5008 HD machine (Fresenius Medical Care, Bad Homburg, Germany)
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Calgary
Sinusitis
Endoscopic Sinus Surgery for Refractory Chronic Sinusitis
Chronic sinusitis is a disease involving severe swelling of your facial sinuses and nasal cavity. Chronic sinusitis is a common disorder and roughly 5% of adult men and women have chronic sinusitis in Canada.
- Trial name
- NCT02506426
- Testing
- Endoscopic sinus surgery + Septoplasty, Septoplasty alone
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Joint Instability, Shoulder Dislocation
Arthroscopic Versus Open Stabilization for Traumatic Shoulder Instability
The purpose of this study is to compare arthroscopic and open shoulder stabilization procedures by measuring the disease-specific quality of life outcome in patients with traumatic unidirectional anterior instability of the…
- Trial name
- NCT00251264
- Testing
- Open stabilization, Arthroscopic stabilization
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- University of Calgary
Shoulder Dislocation
Electrothermal Arthroscopic Capsulorrhaphy (ETAC) and Open Inferior Capsular Shift in Patients With Shoulder Instability
This trial will compare the effectiveness of electrothermal arthroscopic capsulorrhaphy (ETAC) to the current reference standard procedure, open inferior capsular shift (ICS), for the treatment of shoulder instability caused by…
- Trial name
- NCT00251160
- Testing
- Electrothermal arthroscopic capsulorrhaphy (ETAC), Open inferior capsular shift (ICS)
- Where
- 7 sites in Canada
- Volunteers
- 58 people
- Sponsor
- University of Calgary
Gastroparesis
Temporary Gastric Electrical Stimulation for Gastroparesis
This is a prospective study of temporary gastric mucosal electrical stimulation (tGES) in 30 patients with gastroparesis (GP). After a 7 day baseline assessment of symptoms, subjects will have an endoscopically-placed tGES lead…
- Trial name
- NCT01054794
- Testing
- Gastric mucosal stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Gastroesophageal Reflux
An Assessment of pH Testing Methods
Gastroesophageal reflux disease (GERD) is a common and potentially debilitating disorder. Typical symptoms include heartburn and regurgitation of acid tasting substances.
- Trial name
- NCT01364610
- Testing
- Bravo, Standard Care
- Where
- 2 sites in Canada
- Volunteers
- 86 people
- Sponsor
- University of Calgary
Atrial Fibrillation, Cardiac Pacing, Artificial
Dual Chamber Versus Single Chamber Cardiac Pacing in People 80 Years of Age and Older
Of the 19,000 pacemakers implanted across Canada in 2002, 1/3 of them were for patients 80 years and older. This is the fastest growing segment of our population, yet no study has specifically been done in this age group to…
- Trial name
- NCT00116987
- Testing
- Dual chamber cardiac pacemaker, Single chamber cardiac pacemaker
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
Sport Injury
The Effect of a Behavioural Intervention on Injury Prevention Program Adherence in Female Youth Soccer
Soccer accounts for more than 10% of all sport injuries in youth requiring medical attention. The injury rates in youth soccer where there is no established injury prevention program are estimated at 22-30 injuries/100…
- Trial name
- NCT01817049
- Testing
- HAPA-based coach education workshop
- Where
- Canada
- Volunteers
- 214 people
- Sponsor
- University of Calgary
Perinatal Stroke, Cerebral Palsy
Enhancing Motor Plasticity After Perinatal Stroke Using tDCS
The purpose of this study is to test tDCS (transcranial direct current stimulation), a type of non-invasive brain stimulation, to determine whether it can improve motor function in children with perinatal stroke and hemiparesis.
- Trial name
- tDCS (NCT02170285)
- Testing
- Interventional TDCS
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Calgary
Myocardial Infarction
Post Conditioning in PCI for Acute ST Elevation Myocardial Infarction
The purpose of this trial is to compare post-conditioning to standard angioplasty (50/50 chance) in patients who present with an acute heart attack and are taken directly for an angioplasty procedure.
- Trial name
- NCT00334373
- Testing
- Post conditioning
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary