Clinical trials: sponsored by University of Calgary
Diabetes Mellitus
Diabetes Exercise and Lifestyle Trial
The objective of this study is to determine the effects of supervised combined aerobic and resistance training, and the effects of stage-matched written materials delivered by mail or internet, alone or in combination, on…
- Trial name
- DEAL (NCT00877864)
- Testing
- High volume combined aerobic/resistance exercise, Low volume combined aerobic/resistance exercise, High volume combined A/R exercise, printouts, pedometers
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Hepatitis c
Pegylated Interferon Plus Ribavirin in the Treatment of Active and Past Intravenous Drug Users Infected With Hepatitis C
Hepatitis C infects as many as 300,000 Canadians. Up to 25% of those infected will develop cirrhosis and be at risk for liver failure and liver cancer.
- Trial name
- NCT00203606
- Testing
- pegylated interferon alfa-2a ( Roche) and ribavirin
- Where
- 2 sites in Canada
- Volunteers
- 66 people
- Sponsor
- University of Calgary
EBUS-TBNA Training Methods
Evaluation of Clinical Endobronchial Ultrasound Skills Following Clinical Versus Simulation Training.
Bronchoscopy is a procedure whereby a small flexible camera is used to inspect and biopsy abnormalities in the lungs. Linear endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) is a revolutionary diagnostic…
- Trial name
- NCT01269931
- Testing
- EBUS-TBNA
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Neck Dissection
Use of the Harmonic Scalpel in Neck Dissection
Neck dissection is the main technique used by head and neck surgeons to treat known or suspected metastatic cancer to the neck. The traditional radical neck dissection was effective at treating metastatic cancer to the neck…
- Trial name
- NCT00875953
- Testing
- standard neck dissection, Harmonic Scalpel Dissection
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Calgary
Aneurysmal Subarachnoid Hemorrhage, Intraventricular Hemorrhage
Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage
The proposed study is to evaluate the acceleration the clearance of intraventricular blood (IVH) and subarachnoid hemorrhage (SAH) following ruptured intracranial aneurysms, thereby ameliorating complications, such as cerebral…
- Trial name
- NCT01098890
- Testing
- Tissue Plasminogen Activator
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Traumatic Brain Injury
Safety Study of Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Traumatic Brain Injury: Dosing Tier 1
Prospective, Open Label, Cohort Study in Traumatic Brain Injury Patients. The goal of this study is to assess the safety of NTx®-265.
- Trial name
- NCT01239706
- Testing
- NTx 265
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Pain, Pain, Postoperative
Study of Whether 15 mg Dose of Ketorolac IV is as Effective as a 30 mg Dose.
The primary aim of this study is to show the non-inferiority of 15 mg intraoperative dose of ketorolac as compared to the standard 30 mg ketorolac by looking at the VAS scores 4 hours after an adult spine surgery.
- Trial name
- NCT01230463
- Testing
- Ketorolac Tromethamine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Chronic Sinusitis
The Effect of Tranexamic Acid on Intraoperative and Post-Operative Bleeding in Functional Endoscopic Sinus Surgery
Sinus surgery is a common, day surgery procedure performed by general and subspecialty trained otolaryngologists. In most cases, this is a safe surgery with a low incidence of complications.
- Trial name
- NCT00671281
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- University of Calgary
Exfoliation Syndrome, Ocular Hypertension
Randomized Prospective Study of Selective Laser Trabeculoplasty (SLT) Versus Argon Trabeculoplasty (ALT) in Patients With Pseudoexfoliation Glaucoma and Ocular Hypertension
Multi-center, prospective, randomized, controlled clinical trial to compare selective laser trabeculoplasty (SLT) and Argon laser trabeculoplasty (ALT) in pseudoexfoliation glaucoma and ocular hypertension patients.
- Trial name
- SLT (NCT01126203)
- Testing
- SLT, ALT
- Where
- 5 sites in Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Stress
Does a Portable Biofeedback Tool Reduce Physician Stress?
Given the nature of their work duties and work environment, physicians often experience stress within the workplace and chronic stress negatively impacts physician wellness.
- Trial name
- NCT01067183
- Testing
- portable biofeedback tool and relaxation breathing technique
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cardiovascular Diseases, Hypertension
U-CHAMP: Urban Cardiovascular Health Assessment and Management Program
High blood pressure, elevated blood glucose and high cholesterol are related to the increased risk of stroke and heart disease. Many studies have shown that this risk can be significantly reduced by lowering blood pressure, blood…
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia, Hyperglycemia
- Trial name
- U-CHAMP (NCT00626041)
- Testing
- participant referral to primary care network physician
- Where
- 2 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
ACL Reconstruction
Home Vs. Physiotherapy Supervised Rehabilitation After ACL Reconstruction
This study was designed to determine whether or not there were any differences in knee range of motion, both statically and during gait, sagittal plane knee laxity, and quadriceps and hamstrings strength in patients three months…
- Trial name
- NCT00564837
- Testing
- Home-based rehabilitation program, Physiotherapy-supervised rehabilitation program
- Where
- Canada
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Diabetic Neuropathies
Efficacy Study of Nabilone in the Treatment of Diabetic Peripheral Neuropathic Pain
Neuropathic pain occurs as a result of damage or disease of the peripheral or central nervous system. Regardless of its cause, neuropathic pain (NeP) leads to a characteristic clinical picture characterized by ongoing pain with…
- Trial name
- NCT01035281
- Testing
- Nabilone, flexible dosing
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Chronic Rhinosinusitis
Effect of Sinufoam-Dexamethasone Mixture on Post Endoscopic Sinus Surgery Outcomes
Dexamethasone added to sinufoam, which is placed in the ethmoid cavity at the completion of endoscopic sinus surgery, will improve sinonasal mucosal healing.
- Trial name
- NCT01024075
- Testing
- Dexamethasone, Saline
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Epistaxis
Minimally Invasive Control of Epistaxis (MICE)
Epistaxis is a common disorder with 60% of the population suffering from one episode and 10% of these cases requiring medical attention.
- Trial name
- MICE (NCT00666471)
- Testing
- MICE, SPA ligation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Calgary
Chronic Sinonasal Symptoms
The Use of Oral N-Acetyl Cysteine for the Treatment of Chronic Sinonasal Symptoms
Chronic sinonasal symptoms (CSNS), such as coughing, throat clearing, nasal obstruction, crusting, dryness and discharge are extremely common in the general population.
- Trial name
- NCT00866866
- Testing
- N-Acetyl Cysteine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Brain Injuries, Traumatic
Proteomics of Severe Traumatic Brain Injury: A Feasibility Study
The purpose of this study is to: 1. Determine the temporal course of matrix metalloproteinase (MMP) expression in patients wiht severe traumatic brain injury 2.
- Trial name
- NCT00522496
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Calgary
Neuropathic Pain
Intravenous Immunoglobulin (IVIG) for Resistant Neuropathic Pain
This project addresses a vexing problem that has alluded the best efforts of the medical/scientific community: treatment of resistant neuropathic pain.
- Trial name
- NCT00850005
- Testing
- Intravenous immunoglobulin, Normal Saline
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary