Clinical trials: sponsored by University of Calgary
Type 1 Diabetes
Diabetes Transition Coordinator Study
The goal of this interventional study is to assess the effects and evaluate the implementation of a pediatric to adult care transition intervention in youth with T1D on clinical, patient-reported, and implementation outcomes…
- Trial name
- NCT06300047
- Testing
- Non-Medical Transition Coordinator
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- University of Calgary
Sleep Disturbance, Aging
Sleep Quality in Assisted-Living Residents
Assisted living residents who have sleep disturbances are at great risk of developing cognitive impairments. The identification of factors that increase sleep problems in this population is the first step towards improving sleep…
- Trial name
- NCT04400617
- Testing
- Cross-sectional assessments to examine the relationship among sleep quality, functional/physical capacity, and cognitive performance.
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Type 1 Diabetes
Prebiotics in Patients With Type 1 Diabetes
Evidence suggests that prebiotic fibre can correct dysbiosis, reduce intestinal permeability and improve glycemic control. The investigators hypothesize that microbial changes induced by prebiotics contribute to gut and endocrine…
- Trial name
- NCT04963777
- Testing
- Prebiotic
- Where
- 3 sites in Canada
- Volunteers
- 144 people
- Sponsor
- University of Calgary
Postural Orthostatic Tachycardia Syndrome (POTS)
aVNT in POTS - Pilot
Autonomic nervous system imbalance causes postural tachycardia and related cardiac symptoms in Postural Orthostatic Tachycardia Syndrome (POTS). The impact of POTS is more far-reaching than postural tachycardia.
- Trial name
- NCT07026643
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Pain, Delirium in the Intensive Care Unit
Therapeutic Cuddling in Critically Ill Children
2.1 CONTEXT Pain and agitation are common comorbidities of pediatric critical illness due to both underlying disease processes and ICU related therapies.
- Trial name
- THE ChICKS (NCT07562048)
- Testing
- Therapeutic cuddling, Standard of care
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- University of Calgary
Anxiety
Effect of SPG Block for Patients With Anxiety at Electronic Dance Music Festivals
The goal of this clinical trial is to learn about the effect of a sphenopalatine ganglion (SPG) block in anxious patients at electronic dance music festivals.
- Trial name
- NCT05729503
- Testing
- Lidocaine 2% Injectable Solution
- Where
- 4 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Calgary
Postural Orthostatic Tachycardia Syndrome
Low Dose Naltrexone Use in Patients With POTS
Many patients with Postural Orthostatic Tachycardia Syndrome (POTS) experience debilitating fatigue and this significantly impacts their daily lives.
- Trial name
- NCT05363514
- Testing
- Low Dose Naltrexone, Microcrystalline cellulose
- Volunteers
- 80 people
- Sponsor
- University of Calgary
Chronic Pain, Drug Dependence of Morphine Type
Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
The proposed clinical trial will address the problem of opioid withdrawal. Opioids are essential for pain-relief in the short term, but their continued use is associated with a host of adverse effects.
- Conditions
- Chronic Pain, Drug Dependence of Morphine Type, Symptom, Withdrawal
- Trial name
- NCT04939623
- Testing
- Probenecid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Sickle Cell Disease, Stem Cell Transplant Complications
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
The aim of this study to evaluate the safety and efficacy of a nonmyeloablative conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with sickle cell disease (SCD) who have a…
- Conditions
- Sickle Cell Disease, Stem Cell Transplant Complications, Red Blood Cell Disorder, Pure Red Cell Aplasia
- Trial name
- Sickle-AID (NCT03214354)
- Testing
- Alemtuzumab, Total Body Irradiation, Sirolimus
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Cancer
Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes.
- Trial name
- RESPONd (NCT07024329)
- Testing
- Remote Symptom Monitoring and Management, Clinic Team Huddle
- Where
- 4 sites in Canada
- Volunteers
- 1,055 people
- Sponsor
- University of Calgary
Transplantation
Transplant Wellness Program
Wellness is defined as the active pursuit of activities, choices and lifestyles that lead to a state of overall health. Prehabilitation, or using rehabilitation in the period before surgery, can improve the pre, during, and post…
- Trial name
- TWP (NCT06367244)
- Testing
- Transplant Wellness Program - Kidney and Liver
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- University of Calgary
Choking, Airway Obstruction
Evaluation of Foreign Body Airway Obstruction Interventions Through Simulation
WHY IS THIS STUDY BEING DONE? Little is known about the best treatment for choking. New airway clearance devices like LifeVac© and Dechoker© are being sold to help a choking person.
- Trial name
- NCT06227234
- Testing
- Dechoker, LifeVac, Abdominal Thrusts
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Biliary Disease, Choledocholithiasis
Optimizing the Evaluation and Management of Patients With Suspected Choledocholithiasis
Choledocholithiasis (stone(s) in the common bile duct) is common. Untreated or missed, choledocholithiasis has high morbidity and mortality.
- Trial name
- NCT05141916
- Testing
- Endoscopic Retrograde Cholagiopancreatography (ERCP)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of Calgary
Biliary Disease, Pancreatic Diseases
Calgary Registry for Advanced and Therapeutic Endoscopy
The aim of the Calgary Registry for Advanced and Therapeutic Endoscopy (CReATE) is to be a high-fidelity prospective multi-centre registry.
- Trial name
- CReATE (NCT04259580)
- Testing
- Endoscopic retrograde pancreatography (ERCP)
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- University of Calgary
Alzheimer Disease, Dementia
Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias
The estimated annual cost of dementia in Canada is $15 billion, with a projected cumulative economic burden of $800 billion by 2038.
- Trial name
- BIMII (NCT03035851)
- Testing
- Aerobic exercise, Stretch and Strength
- Where
- Canada
- Volunteers
- 264 people
- Sponsor
- University of Calgary
ERCP
IV Fluids and Post-ERCP Pancreatitis
Aggressive intravenous hydration has been shown in randomized trials to prevent post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP), though studied regimens are often impractical.
- Trial name
- NCT05211206
- Testing
- IV fluids
- Where
- Canada
- Volunteers
- 13,000 people
- Sponsor
- University of Calgary
Bile Leak
The Need for Repeat ERCP After Endoscopic Treatment of Postsurgical Biliary Leaks
Post-surgical biliary leaks are relatively common after surgeries associated with hepatobiliary health. Left untreated, biliary leaks can lead to significant morbidity.
- Trial name
- NCT05141942
- Testing
- Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Post-ERCP Acute Pancreatitis
Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).
- Trial name
- STRIPE (NCT06260878)
- Testing
- Intravenous Ringer's lactate
- Where
- Canada
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pulmonary Aspiration
Semaglutide and Preoperative Residual Gastric Volumes
Given the pharmacodynamic and pharmacokinetic properties of glucagon-like peptide-1 (GLP-1) agonists, the Canadian Anesthesiologists' Society has recognized that patients on GLP-1 agonists may have an increased aspiration risk…
- Trial name
- NCT06263595
- Testing
- gastric antral sonography
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary
Cerebral Palsy, Perinatal Stroke
Home-based Early Intensive Hemiparesis Therapy: Engaging Nurture
The purpose of the study is to assess implementation and effectiveness of a caregiver-delivered rehabilitation intervention for infants and toddlers with cerebral palsy.
- Trial name
- HEIGHTEN (NCT05346887)
- Testing
- Home-based Therapy
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary