Clinical trials: sponsored by University of Cincinnati
ADHD, Substance Abuse
Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)
The purpose of this study is to determine the efficacy of osmotic-release methylphenidate (OROS-MPH) versus placebo for the treatment of ADHD in adolescents with SUD.
- Trial name
- NCT00264797
- Testing
- Methylphenidate (OROS-MPH)
- Where
- 12 sites in United States
- Volunteers
- 303 people
- Sponsor
- University of Cincinnati
Healthy, Attention
Effect of 8-Week Dietary DHA Supplementation on Cerebral Blood Flow and Metabolic Function
The goal of this study is to determine if 8-week dietary treatment with the omega-3 fatty acid docosahexaenoic acid (DHA) improves attention performance and associated cortical activity and metabolism in 8 - 10 year old males…
- Trial name
- NCT00662142
- Testing
- docosahexaenoic acid
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Sarcoidosis, Pulmonary Arterial Hypertension
Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
Patients with advanced sarcoidosis often develop pulmonary hypertension. Pulmonary hypertension is a condition where the right side of the heart has to push the blood though the lungs at a higher pressure than normal.
- Trial name
- BOSAPAH (NCT00581607)
- Testing
- Bosentan
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Cincinnati
Sarcoidosis, Pulmonary Arterial Hypertension
Inhaled Iloprost for Sarcoidosis-associated Pulmonary Hypertension
This trial will study the treatment of sarcoidosis-associated pulmonary arterial hypertension with inhaled iloprost, a drug approved for primary pulmonary arterial hypertension.
- Trial name
- NCT00403650
- Testing
- Iloprost
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Sarcoidosis, Cutaneous Sarcoidosis
The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis
To determine whether CC-10004, a phosphodiesterase inhibitor, is useful in treating chronic cutaneous sarcoidosis.
- Trial name
- NCT00794274
- Testing
- CC-100004
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Cincinnati
Traumatic Brain Injury, Elevated Intracranial Pressure
Hypertonic Saline vs. Mannitol for Elevated Intercranial Pressure
This study examines the role of osmotic agents in controlling brain swelling in brain injured individuals. Two osmotic agents -- mannitol and hypertonic saline -- are in common use, and they will be compared in the context of a…
- Trial name
- NCT01111682
- Testing
- Mannitol, Hypertonic Saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Cincinnati
Task Saturation
Enhanced Critical Care Air Transport Team Training for Mitigation of Task Saturation
This study involves two tasks. The first involves observation of patient care during simulated aeroevacuation missions in order to gauge task saturation.
- Trial name
- NCT01628224
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Cincinnati
Multiple Trauma
Effects of Omega-3 Fatty Acid Supplementation on Inflammatory Response in Multisystem Trauma Patients
This study will evaluate the effects of omega-3 fatty acid supplementation on inflammation in trauma patients. The main hypothesis is that such supplementation will reduce the presence of biomarkers of systemic inflammation, as…
- Trial name
- NCT01477697
- Testing
- Omega-3
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Traumatic Brain Injury
Effects of Transport on Patients With Traumatic Brain Injury
Hospitalized patients are often moved from their rooms to other hospital locations, particularly imaging facilities. For patients with traumatic brain injury, such movements may raise the risk of secondary brain injuries.
- Trial name
- NCT01077089
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Cincinnati
HPV Vaccine Acceptability
A Health Belief Model Based Intervention to Increase Human Papilloma Virus (HPV) Vaccination Among College Men
The purposes of this study are to (1) identify predictors of Human papillomavirus (HPV) vaccine acceptability among college men based on the Health Belief Model through focus groups, (2) triangulate focus group results with a…
- Trial name
- NCT01431079
- Testing
- HPV vaccine acceptability
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Depression, Healthy
Quetiapine in Melancholic Depression
In summary, the investigators propose to integrate fMRI assessments within a clinical trial of quetiapine XR in patients with melancholic depression in order to test the predictions that: 1.
- Trial name
- NCT01200901
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Patient/Ventilator Asynchrony
Study to Measure the Prevalence of Asynchrony In Mechanically Ventilated Patients
This study will examine the prevalence of patient-ventilator asynchrony and its determinants. Mechanically ventilated trauma patients often experience asynchrony when their pattern of breathing does not match the triggering of a…
- Trial name
- Asynchrony (NCT01049958)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Cincinnati
ADHD, Smoking
Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation…
- Trial name
- NCT00253747
- Testing
- Osmotic-Release Methylphenidate
- Where
- 6 sites in United States
- Volunteers
- 255 people
- Sponsor
- University of Cincinnati
Heroin Dependence, Opiate Dependence
Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction
The planned research will adapt an intervention of known efficacy to target a new outcome of significant importance to public health.
- Conditions
- Heroin Dependence, Opiate Dependence, Substance Dependence
- Trial name
- NCT00609089
- Testing
- CRAFT-T, Treatment as usual
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Cincinnati
Stroke
Interventional Management of Stroke (IMS) II Study
The purpose of this study is to examine the effects of delivering intra-arterial recombinant tissue plasminogen activator (rt-PA) and ultrasound to the site of the blood clot blocking blood flow to the brain of stroke patients.
- Trial name
- NCT00243906
- Testing
- Recombinant tissue plasminogen activator, Low-intensity ultrasound
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Cincinnati
Mood Disorders
A Study of Quetiapine for the Treatment of Mood Disorders in Adolescents
The purpose of this research study is to obtain preliminary data regarding the effectiveness, tolerability, and safety of quetiapine therapy for adolescents who have a mood disorder and have at least one parent with bipolar…
- Trial name
- NCT00221468
- Testing
- quetiapine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Polycystic Ovary Syndrome, Normal Volunteers
Proteomics & Glyco-Proteomic Analysis of Follicular Fluid
To the best of the investigators knowledge, exhaustive characterization of the low and high abundant proteins and glyco-proteins of the Follicular Fluid (FF) has not yet been achieved.
- Trial name
- NCT01487486
- Testing
- IVF Antagonist Protocol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Surgical Site Infection in Obese Women Undergoing C-section
Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery
The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section.
- Trial name
- SSI (NCT01194115)
- Testing
- cephalexin & metronidazole
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- University of Cincinnati
Pressure Ulcers
Interdisciplinary Mobility Approach To Reduction Of Facility-Acquired Pressure Ulcers
Musical reminder will raise compliance with mobility in the long-term care setting and reduce facility-acquired pressure ulcers.
- Trial name
- TEAM (NCT01008254)
- Testing
- Musical prompt, Delayed musical prompt, No musical prompt
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Schizophrenia, Fatty Acid Deficiency
Omega-3 Fatty Acid Deficiency Replacement in Early Schizophrenia
The purpose of this research study is to find out what effects (good and bad) that omega-3 fatty acids has on schizophrenia.
- Trial name
- NCT00585390
- Testing
- Omega-3 Fatty Acids, EPA fish oil concentrate; DHA fish oil concentrate
- Where
- United States
- Sponsor
- University of Cincinnati