Clinical trials: sponsored by University of Cincinnati
Alcohol Consumption, Anxiety
Motivational and Cognitive Intervention for College Drinkers
In the proposed project the investigators will develop and test a novel brief intervention targeting college students who drink heavily to cope with anxiety and depression, a behavior that increases risk for the development of…
- Conditions
- Alcohol Consumption, Anxiety, Depression
- Trial name
- MCID (NCT01204229)
- Testing
- Motivational and Cognitive Intervention for Drinkers (MCID), Brief Motivational Intervention (BMI)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Stroke
Robotic Brace Incorporating Electromyography (EMG) for Moderate Affected Arm Impairment After Stroke
Stroke is the leading cause of disability in the United States. One of the reasons that it is so disabling is because of upper extremity hemiparesis (weakness in one arm), which is commonly seen after stroke.
- Trial name
- NCT01322997
- Testing
- Myomo e100 Robot and repetitive task specific training, Repetitive task specific training (RTP) targeting the affected arm, Myomo e100 neurorobotic brace
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
End Stage Liver Disease
End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)
The purpose of this research study is to see how effective bioelectric impedance analysis (BIA) is in determining body composition (the amount of fat versus muscle in the body) and nutritional status in patients with End Stage…
- Trial name
- NCT00374582
- Testing
- Bodystat Quadscan 4000, bodystat quadscan 400
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Incomplete Spinal Cord Injury
Mental Practice Impact on Gait and Cortical Organization in Spinal Cord Injury (SCI)
Spinal cord injury (SCI) is a disabling condition that impairs fundamental abilities, such as ambulation, respiration, and toileting. Compromised ambulation is a common, devastating impairment following SCI.
- Trial name
- NCT01302522
- Testing
- Mental practice
- Sponsor
- University of Cincinnati
Sarcoidosis
Use of Focalin for Fatigue in Sarcoidosis
Patients diagnosed with chronic sarcoidosis with fatigue for more than 6 months. Sarcoidosis and its treatment can greatly affect your quality of life.
- Trial name
- NCT00361387
- Testing
- d-methylphenidate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Alcoholism, Alcohol Abuse
Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI)
This study is being done to determine if citalopram is safe and effective in the treatment of alcohol dependence. A second purpose is to evaluate whether alcohol dependent individuals who differ in a specific genetic marker…
- Trial name
- NCT00249405
- Testing
- Citalopram + MI
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Cincinnati
Alcohol Consumption, Alcohol Negative Consequences
Brief Intervention for Socially Anxious College Drinkers
The purpose of this study is to develop and test a new brief intervention to reduce heavy drinking and social anxiety in college drinkers.
- Conditions
- Alcohol Consumption, Alcohol Negative Consequences, Social Anxiety
- Trial name
- BISAD (NCT00872118)
- Testing
- Brief Intervention for Socially Anxious Drinkers (BISAD), Enhanced Alcohol Skills Building and Education Program
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Cincinnati
Premature Birth, Premature Labor
Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor
Primary Hypothesis: Acute tocolysis (48 hours) using oral nifedipine is more effective than intravenous magnesium sulfate in prolonging pregnancy in women with preterm labor with intact membranes between 24 and 32 6/7 weeks'…
- Trial name
- NCT00306462
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Attention Deficit Hyperactivity Disorder
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
The purpose of this study is to evaluate the safety and efficacy of two medications--clonidine and methylphenidate--alone or in combination to treat attention deficit hyperactivity disorder in children ages 4 through 6.
- Trial name
- kiddie-CAT (NCT00414921)
- Testing
- clonidine, methylphenidate
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Attention Deficit Disorder With Hyperactivity
Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.
- Trial name
- NCT00031395
- Testing
- clonidine, methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Cincinnati
Stroke
Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial
The purpose of this study is determine the effects of using of a combination of two drugs--integrilin (eptifibatide) and activase (recombinant tissue plasminogen activator, rt-PA, or recombinant t-PA)--to dissolve blood clots in…
- Trial name
- NCT00250991
- Testing
- activase, integrilin
- Where
- 19 sites in United States
- Volunteers
- 94 people
- Sponsor
- University of Cincinnati
Pulmonary Hypertension
Right Ventricular Hypertrophy and Pulmonary Hypertension: A Correlation Analysis
The study hypothesis is that a quantitative index can be derived from Tc-99m myocardial perfusion scans that accurately identifies the presence of left ventricular hypertrophy and pulmonary hypertension.
- Trial name
- NCT00875940
- Testing
- Diagnostic imaging procedures.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Cincinnati
Parkinson Disease
Botulinum Toxin Type A (Botox) in the Management of Levodopa-Induced Peak-Dose Dyskinesias in Parkinson's Disease
The primary objective of this study is to determine whether intramuscular injections of botulinum toxin type A (Botox®) in selected cervical muscles at antidystonic dosages can reduce levodopa-induced peak-dose dyskinesias (LID)…
- Trial name
- NCT00477802
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Cincinnati
Chronic Myeloid Leukemia, Blast Crisis, Acute Myeloid Leukemia
A Study Evaluating the Effects of CLAG With Gleevec in Refractory or Relapsed Acute Myeloid Leukemia
The purpose of this study is to evaluate the safety of combined chemotherapy treatment (CLAG regimen) with Imatinib Mesylate (Gleevec) in patients with AML.
- Trial name
- NCT00594555
- Testing
- Imatinib Mesylate, CLAG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Urethrocystoscopy Skills
Standardized Criteria to Judge Diagnostic Urethrocystoscopy Skills
Develop a tool to objectively quantify technical skills necessary to perform diagnostic cystoscopy (using Objective Structured Assessment of Technical Skills- OSATS).
- Trial name
- NCT00631761
- Testing
- educational workshop, no intervention (usual resident activities)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Cincinnati
Overweight, Obesity
Effect of High Monounsaturated Fat Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes
The purpose of this proposed randomized, controlled trial is to compare the effects of high monounsaturated fat diets and high carbohydrate diets on body weight, body composition, glycemic control, plasma lipids, and other…
- Conditions
- Overweight, Obesity, Type 2 Diabetes
- Trial name
- NCT00622960
- Testing
- High-MUFA diet, High-CHO diet
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Cincinnati
Kidney Transplant
The Paired Donation Consortium Paired Donation Program
The purpose of the protocol is to increase the number of living donor transplants by eliminating immune incompatibilities between donors and recipients through paired donation.
- Trial name
- NCT00374400
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Polyomavirus
Monitoring of Biopsy-Proven Interstitial Polyomavirus Nephritis in Kidney and Kidney Pancreas Transplant Recipients
Evaluate techniques for monitoring the course of interstitial therapy for polyomavirus nephritis in kidney and kidney pancreas transplant recipients by monitoring blood, urine, and renal transplant biopsies of patients affected…
- Trial name
- NCT00374283
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Acid Reflux Disease, Obstructive Sleep Apnea
Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea
The purpose of this study is to determine if using Pantoprazole decreases your daytime sleepiness and improves your reaction time when compared to using a placebo (sugar pill).
- Trial name
- NCT00307944
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Obstructive Sleep Apnea
Study to Determine the Effectiveness of Pillar Palatal Implants to Treat Obstructive Sleep Apnea
The Pillar palatal implant procedure is a minimally invasive and commercially available treatment for mild to moderate obstructive sleep apnea (OSA) in the United States and Europe.
- Trial name
- NCT00307957
- Testing
- Pillar Palatal Implants
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati