Clinical trials: sponsored by University of Cincinnati
Traumatic Brain Injury
Inhaled Nitric Oxide in Brain Injury
This study will evaluate the changes in respiratory mechanics following traumatic brain injury and determine the effect of inhaled nitric oxide on gas exchange.
- Trial name
- NCT03260569
- Testing
- Inhaled Nitric Oxide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Cincinnati
Bipolar Disorder
Bipolar Disorder Measures in Clinical Care
Measurement based care (MBC) is an emerging best practice involving serial assessment of clinical status and using those findings to inform clinical decision making.
- Trial name
- NCT05300919
- Testing
- Measurement based care
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Advanced Adult Primary Liver Cancer, Liver Metastases
Pilot Study to Assess Lung Shunting of Yttrium-90 Microspheres Using PET/CT
This pilot clinical trial studies positron emission tomography (PET)/computed tomography (CT) in finding beads after Yttrium-90 bead therapy in patients with primary liver cancer or cancer that has spread to the liver…
- Conditions
- Advanced Adult Primary Liver Cancer, Liver Metastases, Localized Unresectable Adult Primary Liver Cancer, Recurrent Adult Primary Liver Cancer
- Trial name
- NCT02119065
- Testing
- positron emission tomography, computed tomography
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Eye Cancer
MRI in Diagnosing Solid Tumors of the Eye and Orbit
This study is being done due to a new imaging method that may help others in the future to improve evaluation of diseases in the eye and eye socket and to help make a decision concerning best treatment of the disease.
- Trial name
- NCT01653080
- Testing
- dynamic contrast-enhanced MRI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Cincinnati
Prostate Cancer
3-Tesla MRI in Finding Tumors in Patients With Known or Suspected Prostate Cancer
In standard clinical care, the prostate is imaged by magnetic resonance imaging (MRI) which is a procedure to take pictures of body structures by using a strong magnetic field and radio waves.
- Trial name
- NCT01653093
- Testing
- 3-Tesla magnetic resonance imaging (3T MRI), diffusion-weighted magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Cincinnati
Bladder Cancer
3 Tesla MRI in Patients With Bladder Cancer
RATIONALE: New diagnostic procedures, such as 3 Tesla magnetic resonance imaging (MRI), may help find bladder cancer and learn the extent of disease.
- Trial name
- NCT00938145
- Testing
- Specimen Ultra-High field MRI, chemotherapy, Cystectomy and Lymphadenectomy
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Cincinnati
Bipolar Disorder, Weight Gain
Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine
The primary objective of this study is to examine the efficacy of topiramate in combination with olanzapine for the prevention of weight gain in youth with bipolar disorder.
- Trial name
- NCT00394095
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Cincinnati
Fracture of Posterior Wall of Acetabulum
Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin/Hematocrit
This multi-center, prospective study will evaluate the use of topical tranexamic acid (TXA - Cyklokapron; Pfizer, New York, NY) on pre-operative and post-operative hemoglobin (Hb)/hematocrit (Hct) in patients undergoing operative…
- Trial name
- NCT05357079
- Testing
- Tranexamic Acid, Normal saline
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Cincinnati
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Early Intervention in Cognitive Aging
Nutritional intervention in overweight middle aged individuals with subjective memory complaints.
- Trial name
- NCT02751866
- Testing
- Berry fruit powder OR nutritional ketosis
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Cincinnati
Pulmonary Arterial Hypertension
HRV as a Marker of Treatment Response in PAH Arterial Hypertension
This is a prospective longitudinal cohort study to determine the value of HRV obtained using noninvasive actigraphy to quantify the response to pulmonary vasodilator therapy in newly diagnosed PAH patients
- Trial name
- NCT04451850
- Testing
- Noninvasive actigraphy monitor
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Stroke
Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke
The objective of this study is to determine the optimal training intensity and the minimum training duration needed to maximize immediate improvements in walking capacity in chronic stroke.
- Trial name
- NCT03760016
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Cincinnati
Pediatric Obesity
Healthy Eating for My Infant (HEMI)
Infants from underserved and minority backgrounds are at increased risk for obesity and poor feeding and nutrition outcomes, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT04977947
- Testing
- Healthy Eating for My Infant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Major Depressive Disorder
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder
This pilot clinical trial will evaluate the efficacy and safety of transcutaneous direct current stimulation (tsDCS) in major depressive disorder.
- Trial name
- SPIDEP (NCT03433339)
- Testing
- Active transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
LAM, Lymphangioleiomyomatosis
Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial
This is a study to determine if early, long-term low dose sirolimus is effective for preventing progression to more advanced stages.
- Trial name
- MILED (NCT03150914)
- Testing
- Sirolimus
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Lymphangioleiomyomatosis
Safety and Durability of Sirolimus for Treatment of LAM
The MIDAS study aims to follow male and female LAM patients who are currently taking, have previously failed or been intolerant of, or may (at some time in the future) take mTOR inhibitors (sirolimus or everolimus) as part of…
- Trial name
- MIDAS (NCT02432560)
- Testing
- Sirolimus, Everolimus
- Where
- 20 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Cincinnati
Breast Neoplasm
CanRestoreFunction Cancer-related Fatigue ( CRF )
The goal of this randomized control trial is to determine if participating in an 8-week online cancer-related fatigue management intervention consisting of individualized exercise program, one-on-one goal setting and action plan…
- Trial name
- CRF (NCT05868187)
- Testing
- Exercise, Problem-Solving Session and Education
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
BLS Competence, Debriefing
The Effect of Immediate Versus Delayed Debriefing on Basic Life Support Competence In Undergraduate Nursing Students.
The goal of this clinical trial is to find out if immediate (hot) or delayed (cold) debriefing is better for undergraduate nursing students during Basic Life Support (BLS) training.
- Trial name
- NCT06624449
- Testing
- Cold debriefing, Hot Debriefing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
ACE Inhibitor-Induced Angioedema
Safety and Efficacy of Conestat Alfa for ACE-Induced Angioedema
Angiotensin-converting enzyme inhibitors (ACE-Is), prescribed most often to treat hypertension, have been used extensively since the 1980s.
- Trial name
- NCT06679426
- Testing
- Conestat Alfa
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Anxiety Disorders
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.
- Trial name
- EV-SoPRANO (NCT04221997)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Cancer, Renal Failure
Fernald Community Cohort -18 Year Observational Study
The Fernald Community Cohort consists of the 9782 persons who were enrolled in the Fernald Medical Monitoring Program (FMMP) (1990-2008).
- Conditions
- Cancer, Renal Failure, Diabetes, Cardiovascular Disease
- Trial name
- FCC (NCT02295085)
- Where
- United States
- Volunteers
- 9,782 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati