Clinical trials: sponsored by University of Colorado, Denver
Stroke
Vibrotactile Stimulation for Upper-Extremity Stroke Rehabilitation
The goal of this clinical trial is to investigate upper-extremity vibrotactile stimulation with wearables in stroke patients. The main questions it aims to answer are: Are the wearables well-tolerated by patients? Does the…
- Trial name
- NCT06244719
- Testing
- Vibrotactile Stimulation
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Opioid-use Disorder, Opioid Dependence
Comparing Home, Office, and Telehealth Induction for Medication Assisted Treatment for Opioid Use Disorder
HOMER is a national study comparing three methods of induction for Medication Assisted Treatment (MAT) for Opioid Use Disorder (OUD); home versus office versus telehealth-based inductions.
- Trial name
- HOMER (NCT04664062)
- Testing
- Medication Assisted Treatment
- Where
- 2 sites in United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Staphylococcus Aureus Infection, Surgical Site Infection
Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections
The goal of this study is to test a new way to diagnose and track treatment of spine infections caused by the bacteria Staphylococcus aureus.
- Conditions
- Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
- Trial name
- NCT04897971
- Testing
- Medium enriched for newly synthesized antibodies in spine infection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Age-Related Osteoporosis
Genetic Regulators of Bone Health That Are Unique to Vertebral Bone
Osteoporosis is an age related disease in which a person's bone slowly becomes weaker with time. The bones may become so weak that they break easily such as a fall from standing height.
- Trial name
- NCT05946278
- Testing
- Sample collection for gene expression
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of Colorado, Denver
Healthy Older Adults Ages 60-89
Longitudinal Innate Immunity and Aging Study
This study plans to examine biological bases of cognitive aging. The goals of the study are to better understand how immune system markers, measured in the blood and in the spinal fluid, are related to clinical features of aging…
- Trial name
- LIIA (NCT03944603)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Musculoskeletal Injury, Quality of Life
Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury
This study aims to assess the quality and life and life satisfaction of pediatric and adolescent gymnasts throughout their musculoskeletal injury recovery.
- Trial name
- NCT05110729
- Where
- United States
- Volunteers
- 1,218 people
- Sponsor
- University of Colorado, Denver
Subarachnoid Hemorrhage
Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage
This study evaluates the pharmacokinetic profile of levetiracetam in critically ill patients who have suffered a subarachnoid hemorrhage.
- Trial name
- NCT02866877
- Testing
- Pharmacokinetic modeling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
HIV Infections, Sexually Transmitted Infections
Reducing Disparities in Rural HIV Prevention
HIV and Sexually Transmitted Infection (STI) rates are increasing in rural areas including rural Colorado. Many rural residents find it difficult to access HIV and STI prevention services.
- Trial name
- NCT05319613
- Testing
- Virtual clinical visits with home lab kits and mailed HIV PrEP
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases, Lifestyle Factors
Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
The goal of our pragmatic clinical trial is to compare how well three different strategies might do to reduce risk factors for cardiovascular disease in patients experiencing health disparities.
- Trial name
- NCT06324981
- Testing
- Generic text messages, Interactive AI chatbot text messaging, Proactive pharmacist support
- Where
- 3 sites in United States
- Volunteers
- 2,100 people
- Sponsor
- University of Colorado, Denver
Marginal Zone Lymphoma, Follicular Lymphoma
Ublituximab Followed by Response-driven Addition of Umbralisib for Treatment-naive Follicular or Marginal Zone Lymphoma
This is an open-label, Phase II interventional study in order to assess efficacy and safety of single agent ublituximab as initial therapy for FL (Follicular lymphoma) and MZL (Marginal zone lymphoma ) with response driven…
- Trial name
- NCT04508647
- Testing
- Ublituximab, Umbralisib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Colorado, Denver
Breast Cancer Female
Fertility Changes Due to Cancer: an Investigation of Meaning, Psychological Distress, and Psychologi
Establish the relationship between meaning and psychological distress in young women with breast cancer who experienced reproductive concerns due to cancer diagnosis and treatment and their partners.
- Trial name
- NCT05245162
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Colorectal Cancer
Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors
This study is a two-arm trial, comparing the effects of a virtual 12-week group-based exercise intervention vs. control group on physical activity, physical fitness, and quality of life in colorectal cancer survivors, and explore…
- Trial name
- NCT03781154
- Testing
- Group Exercise
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Colorado, Denver
Blood Pressure, Body Composition
ENRICH Nurse-Family Partnership Study
The overarching goal of the proposed study is to develop and test an enrichment to Nurse-Family Partnership (NFP) using an existing, evidence-based program to improve clients' and their children's cardiovascular health from early…
- Conditions
- Blood Pressure, Body Composition, Blood Sugar, Body Weight
- Trial name
- NCT05798039
- Testing
- ENRICH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ependymoma, Recurrent Childhood, Ependymoma
Study of the Effect of GM-CSF on Macrophages in Ependymoma
This study plans to learn more about the use of Granulocyte Macrophage Colony Stimulation Factor (GM-CSF) on ependymoma tumors. The use of GM-CSF is a potential way of increasing the infiltration of immune cells and this study is…
- Trial name
- NCT04408092
- Testing
- Granulocyte Macrophage Colony Stimulation Factor
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Colorado, Denver
Pregnancy, Obesity
Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth
The purpose of this study is to establish and follow longitudinally a cohort of ethnically diverse pregnant women and their offspring, in order to explore the hypothesis that fetal over-nutrition is associated with obesity…
- Trial name
- NCT02273297
- Testing
- Maternal factors
- Where
- United States
- Volunteers
- 2,821 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Older Adults, Physical Deconditioning
Progressing Home Health Rehabilitation for Older Adults
This research study explores the effects of a progressive, multi-component intervention following a stay in the hospital or rehabilitation facility.
- Trial name
- NCT02905370
- Testing
- Progressive Multi-Component (PMC), Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Colorado, Denver
Opioid Use
Best Practice Alert for Opioid Prescribing
The investigators will embed a developed decision support tool into the electronic health record (EHR) to individualize pain therapy in surgical patients after hospital discharge and test its performance in a pragmatic clinical…
- Trial name
- NCT04446975
- Testing
- BPA
- Where
- United States
- Volunteers
- 21,689 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes, Depression
Depression in Youth Onset Type 2 Diabetes
The main purpose of this study is to compare a group-based interpersonal psychotherapy (IPT) program and a Type 2 Diabetes education program to determine if there are differences in depression levels, diabetes distress, and…
- Trial name
- NCT06285487
- Testing
- Group Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Procedural Anxiety, High Risk Pregnancy
Cognitive Behavioral Intervention to Reduce Procedural Anxiety Among Woman With High Risk Pregnancies With Scheduled Cesarean Deliveries
The goals of this study are to determine the feasibility and efficacy of a brief, single-session cognitive-behavioral intervention for reducing preoperative and postoperative anxiety and for determining satisfaction with the…
- Conditions
- Procedural Anxiety, High Risk Pregnancy, Fetal Complications
- Trial name
- NCT04203082
- Testing
- Exposure Intervention, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Back Pain, Neck Pain
Cannabis Versus Oxycodone for Pain Relief
This study investigates the ability of cannabis to reduce chronic back and neck pain and to reduce sensitivity to an acute painful stimulus. Cannabis will be compared to both oxycodone and a placebo.
- Trial name
- NCT02892591
- Testing
- Cannabis, Oxycodone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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