Clinical trials: sponsored by University of Colorado, Denver
Chronic Illness
Virtually-integrated Co-management Between Complex Care and Community-based Primary Care Providers
This is a pilot trial to test whether tertiary center-affiliated pediatricians with expertise in medical complexity joining medical visits with patients' community primary care providers is feasible and acceptable.
- Trial name
- CoTS (NCT03530709)
- Testing
- videoconferencing
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Nevi and Melanomas
Assessing Gene-Environment Interactions in Clinical Presentation of Nevi and Melanoma
This research study is designed to better understand the role of genetics, sun-exposure and phenotypic factors in melanoma.
- Trial name
- NCT03783325
- Testing
- UV Counseling, UV Photo, Biological Sample
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gram-Positive Bacterial Infections, Gram-Positive Bacteraemia
Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition
The Investigators aim to study the outcomes of serious infections due to vancomycin susceptible infections in gram-positive organisms susceptible to vancomycin in people who use drugs (PWUD).
- Conditions
- Gram-Positive Bacterial Infections, Gram-Positive Bacteraemia, Substance Use Disorders, Intravenous Substance Abuse
- Trial name
- SUDDEN-OUT (NCT04847921)
- Testing
- Dalbavancin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Colorado, Denver
Cancer
Improving Physical Activity Maintenance of Cancer Survivors
Participants enrolled in the BfitBwell Cancer Exercise Program at the University of Colorado Cancer Center will be randomized 1:1 to receive the current BfitBwell program, or BfitBwell plus six, group-based behavior change…
- Trial name
- NCT03976193
- Testing
- BfitBwell program, 6 bi-weekly PA Behavior Change counseling sessions
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Colorado, Denver
Obesity, Insulin Resistance
Microbiome Insulin Sensitivity Study
The Microbiome Insulin Sensitivity Study "MISS" is a pilot study designed to study microbiome composition across puberty and how it relates to insulin sensitivity and secretion in obese girls, who are at increased risk for…
- Conditions
- Obesity, Insulin Resistance, Type2 Diabetes
- Trial name
- MISS (NCT03120871)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Colorado, Denver
Pregnancy, Anesthesia
Continuous Noninvasive Method for Estimating and Predicting Maternal and Fetal Hemodynamic Changes During Regional Anesthesia
Machine learning techniques and algorithms originally developed for use in the field of robotics can be applied to continuous, noninvasive physiological waveform data to discover hidden, hemodynamic relationships.
- Trial name
- NCT01699243
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Intervertebral Disc Degeneration, Osteoarthritis, Spine
Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages.
- Trial name
- NCT03076658
- Testing
- EOS imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Burnout, Professional, Self Compassion
Better Together Physician Coaching to Mitigate Burnout in Male-Identifying Trainees
Better Together Physician Coaching ("Better Together", or "BT"), a 4-month, web-based positive psychology multimodal coaching program was built to decrease burnout in medical trainees.
- Conditions
- Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome
- Trial name
- BTPC (NCT05550753)
- Testing
- Better Together Physician Coaching Program
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vital Signs
A Machine Learning Approach to Continuous Vital Sign Data Analysis
Study hypothesis: Machine Learning algorithms and techniques previously developed for use in the robotics field can be applied to the field of medicine.
- Trial name
- NCT01448161
- Volunteers
- 605 people
- Sponsor
- University of Colorado, Denver
Trauma
Continuous Assessment of Hemodynamic Compensation in Pediatric Trauma Patients
This is an observation study using the Flashback CRI T1 tablet to collect data on compensatory reserve index in pediatric trauma patients.
- Trial name
- NCT04911465
- Testing
- Flashback CRI T1 Tablet
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Burnout, Professional
Better Together Physician Coaching: An Innovative Solution to Medical Trainee Burnout
Burnout refers to feelings of exhaustion, negativism, and reduced personal efficacy resulting from chronic workplace stress. In healthcare, burnout leads to increased medical errors, poorer patient care and negatively affects…
- Trial name
- NCT05222685
- Testing
- Better Together Physician Coaching
- Where
- United States
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adolescent Idiopathic Scoliosis
Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on child health, the etiology of AIS and molecular mechanisms underlying…
- Trial name
- NCT02315729
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Colorado, Denver
Interpersonal Psychotherapy, Polycystic Ovary Syndrome
Interpersonal Psychotherapy in Adolescents With Polycystic Ovary Syndrome
The main purpose of this study is to find out whether taking part in a group-based interpersonal psychotherapy (IPT) program designed to improve mood and lessen stress in girls with PCOS will improve depression, unhealthy eating…
- Trial name
- IPAP (NCT06056453)
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parturition, Fetal Intervention
Evaluation of Compensatory Reserve in Obstetrical Patients
Using a pulse oximeter, the investigators have developed an algorithm that assesses central volume status. Pregnant women present some unique opportunities for us to investigate the algorithm under different circumstances.
- Trial name
- NCT02408588
- Testing
- Pulse oximeter
- Volunteers
- 600 people
- Sponsor
- University of Colorado, Denver
Obesity
Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program
The primary aim of this study is to evaluate the extent to which an exercise intervention timed after diet-induced weight loss (rather than initiated at the same time) improves exercise adherence and long-term weight loss.
- Trial name
- NCT01985568
- Testing
- Sequential BT, Standard BT
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Total Knee Replacement
Novel Strategies for Personalized Clinical Decisions in Knee Arthroplasty
This study will compare the postoperative recovery of two patient cohorts who attended outpatient physical therapy at two clinics in the Greenville, South Carolina area.
- Trial name
- NCT05900453
- Testing
- Clinical decision support (CDS) tool
- Where
- United States
- Volunteers
- 675 people
- Sponsor
- University of Colorado, Denver
Melanoma
Ipilimumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma
The purpose of this study is to assess the safety and efficacy of combined treatment with Ipilimumab and all-trans retinoic acid (ATRA) in melanoma patients.
- Trial name
- NCT02403778
- Testing
- VESANOID, Ipilimumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes, Insufficient Sleep
Assessment of Sleep and Sleep Disruptors in Adolescents With Type 1 Diabetes
The goal of this study is to identify causes of insufficient sleep and sleep disruptors in adolescents with type 1 diabetes. For this study, adolescents will wear an actigraphy watch and complete sleep diaries for seven days.
- Trial name
- NCT05370339
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Colorado, Denver
Breast Cancer Female
Facial Skin Health Tracking Feasibility in Breast Cancer Patients
This feasibility study will assess if tracking objective and subjective facial skin changes over time is acceptable to pre and perimenopausal women undergoing chemotherapy and/or endocrine therapy for breast cancer.
- Trial name
- NCT04035408
- Testing
- Skin health assessment
- Where
- United States
- Sponsor
- University of Colorado, Denver
Motor Activity, Health Behavior
Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes
This study plans to learn more about physical activity and physical function in sedentary older adults with type 2 diabetes.
- Conditions
- Motor Activity, Health Behavior, Diabetes Mellitus, Type 2
- Trial name
- NCT02473926
- Testing
- Physical Activity, Questionnaires
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Colorado, Denver
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