Clinical trials: sponsored by University of Florida
Healthy
LXRA Gene Polymorphisms and Response to Fenofibrate
This is a research study of how a cholesterol medication known as fenofibrate works differently in people with different genetic backgrounds.
- Trial name
- NCT00644592
- Testing
- Fenofibrate capsule daily for 4 weeks, Fenofibrate
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Inflammation
Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis
The purpose of the study is to test whether atorvastatin (also known as Lipitor) has anti-inflammatory effects in people with no known heart disease or high cholesterol.
- Trial name
- NCT00361283
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aphasia, Cerebrovascular Accident
Treating Intention In Aphasia: Neuroplastic Substrates
The purpose of this study is to determine if an "intentional act" improves treatment response for patients with nonfluent aphasia. The treatment involves naming pictures and saying members of categories.
- Trial name
- NCT00567242
- Testing
- Word-finding with intention component, Word-finding with no intention component
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Infection
Timing of Antibiotic Prophylaxis for Cesarean Deliveries
The current standard of care to prevent post partum infectious morbidities is to administer antibiotic prophylaxis to all women undergoing a cesarean delivery.
- Trial name
- NCT00805545
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson's Disease
Masked Faces in Parkinson Disease: Mechanism and Treatment
The purpose of this study is to examine the effectiveness of high intensity respiratory muscle strength training in treating blunted facial expression in people with Parkinson disease.
- Trial name
- NCT00350402
- Testing
- Respiratory muscle strength training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Florida
Hormone Refractory Prostate Cancer
RNActive®-Derived Therapeutic Vaccine
This is a Phase I/IIa open, uncontrolled, prospective study, to be conducted in an out-patient setting. The present study is one of two clinical trials of the RNActive®-derived vaccine CV9103 being conducted concurrently in the…
- Trial name
- NCT00906243
- Testing
- CV9103
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Drug Interaction
PPI and Clopidogrel Response
Clopidogrel, in combination with aspirin, is currently the recommended treatment for secondary prevention of ischemic events in high-risk patients and for prevention of coronary artery stent thrombosis.
- Trial name
- NCT01170533
- Testing
- omeprazole and pantoprazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 2 Diabetes Mellitus, Coronary Artery Disease
Aspirin Dosing in Diabetic Patients
Since diabetic platelets are characterized by an enhanced turnover rate, it may be hypothesized that an increase in the frequency, rather than the dose, of drug administration may be a more effective strategy to inhibit platelet…
- Trial name
- NCT01201785
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Lung Cancer
Stereotactic Body Radiation Therapy (SBRT) for Lung Tumors
The purpose of this research study is to determine if Stereotactic Body Radiation Therapy(SBRT) is a good way to treat tumors near the thorax.
- Trial name
- NCT00632281
- Testing
- Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Florida
Non-Hodgkin's Lymphoma, Follicular Lymphoma
Study to Treat Relapsed Follicular Non-Hodgkin's Lymphoma With Radiation and Bexxar
The purpose of this study is to determine the feasibility of treating relapsed follicular lymphoma with a combination of Bexxar and External Beam Radiotherapy (EBRT).
- Trial name
- NCT00475332
- Testing
- Iodine I -01 Tositumomab (Bexxar), External Beam Radiation Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Spinal Tumors
Stereotactic Body Radiation Therapy (SBRT) for Tumors Near the Spinal Cord
The purpose of this research study is to determine if Stereotactic Body Radiation Therapy (SBRT) is a good way to treat tumors near the spinal cord.
- Trial name
- NCT00631670
- Testing
- Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Disorder of Vitamin B12
Evaluation of Holotranscobalamin as an Indicator of Vitamin B12 Absorption
Vitamin B12 is an essential nutrient that the body needs for cells to divide and function normally. Individuals may develop a deficiency of vitamin B12 by either limiting the amount in the diet or by decreased vitamin B12 intake…
- Trial name
- NCT00235573
- Testing
- Vitamin B12
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Florida
Vascular Closure
Patient Comfort With Vascular Closure
The purpose of this research study is to collect information on the amount of discomfort patients experience with one of two different vascular blood vessel closure devices, the MynxM5 Vascular Closure Device and the Angio-Seal…
- Trial name
- NCT00998023
- Testing
- Mynx Vascular Closure Device, AngioSeal Vascular Closure Device
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Florida
Asthma
Dose-response of Inhaled Formoterol Using Methacholine Challenge as a Bioassay
The purpose of this study is to find out whether a difference between two doses of formoterol can be detected by methacholine challenge.
- Trial name
- NCT00643578
- Testing
- formoterol, Dry Powder Inhaler (Twisthaler)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Florida