Clinical trials: sponsored by University of Florida
Cough, Parkinson's Disease
Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease
The purpose of this research study is to test cough function in individuals with Parkinson's disease and healthy older adults. Cough is a complex, defensive function which involves movement of the chest and lungs.
- Trial name
- NCT02183519
- Testing
- Capsaicin, Voluntary cough test
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Florida
Contrast Allergies
Reactions to Contrast Media (CM) Administered at the Time of the Endoscopic Retrograde Cholangiopancreatography (ERCP)
The aim of this study is to prospectively document the incidence of CM adverse reactions at the time of ERCP and to determine whether various perceived risk factors are predictive of adverse reaction.
- Trial name
- NCT00900640
- Testing
- ERCP as medically indicated by subjects referring physician
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Florida
Nerve Sheath Tumors, Neurofibroma
Proton Radiation Therapy for Spinal Tumors
The purpose of this study is to determine if Proton Therapy can provide effective and safe treatment for Malignant Peripheral Nerve Sheath Tumors of the spine and Neurofibromas of the spine.
- Trial name
- NF01 (NCT01567787)
- Testing
- Proton Radiation for MPNST, Proton Radiation for neurofibromas
- Sponsor
- University of Florida
Soft Tissue Sarcomas
Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas
The goal of this study is to evaluate the effects of temozolomide and radiation combination in the treatment intended of soft tissue sarcomas.
- Trial name
- SA02 (NCT00881595)
- Testing
- Chemoradiotherapy Temozolomide, Proton therapy, Proton Chemoradiotherapy followed by surgery
- Sponsor
- University of Florida
Retroperitoneal Sarcoma
Preoperative Proton Radiotherapy for Retroperitoneal Sarcoma
The goal of this study is to evaluate radiation treatment intended to increase the chance of curing your sarcoma and decrease the side effects of proton therapy.
- Trial name
- SA03 (NCT00901836)
- Testing
- Preoperative proton therapy, Surgery
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Nasopharynx Cancer
Photon/Proton Radiation Therapy for Carcinoma of the Nasopharynx
The purpose of this study is to collect outcomes information to see what effects photon/proton beam radiation has on nasopharynx cancer.
- Trial name
- NP01 (NCT00797290)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Survival of Probiotics During GI Transit, GI Symptoms
Acidophilus Pearls Fecal Recovery Study
Commercial probiotics can be delivered in numerous forms. The two most common delivery forms are similar to the two product formats to be tested.
- Trial name
- NCT02001610
- Testing
- Acidophilus pearls, Hard shell gelatin capsules
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heart Failure
Cardiac Resynchronization Therapy (CRT) and Left Ventricular Assist Devices (LVAD) Therapy
Cardiac resynchronization therapy (CRT) or biventricular pacing is a useful treatment for heart failure and those suffering from arrhythmias.
- Trial name
- NCT02083419
- Testing
- LVAD CRT
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Malignant Neoplasm of Skin Head and Neck
Photon/Proton Radiation Therapy for Carcinoma of the Skin of the Head and Neck
The purpose of this study is to collect information from the questionnaire and your medical records to see what effects the proton radiation has on you and your cancer and collect and analyze morbidity outcomes: Incidence of…
- Trial name
- SK01 (NCT00797043)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Florida
Oropharyngeal Cancers
Photon/Proton Radiation Therapy for Oropharyngeal Cancers
The purpose of this study is to collect information from the questionnaire and medical records to see what effects proton radiation has on cancer and collect and analyze morbidity outcomes: incidence of xerostomia (dry mouth) and…
- Trial name
- OP01 (NCT00797446)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Vitamin B6 Deficiency
Vitamin B6 Effects for Women Taking Birth Control Pills
Chronically inadequate B6 nutritional status is associated with aberrant one-carbon (1C) metabolism and health. Plasma pyridoxal phosphate (PLP) >30 nmol/L often has been considered to be the cutoff indicative of nutritional…
- Trial name
- NCT01128244
- Testing
- Vitamin B6, Infusion of labeled serine, methionine and leucine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Arterial Stiffness in Youth With Type 1 Diabetes
Arterial Stiffness in Type I Diabetes Mellitus
Using radial artery tonometry to study arterial stiffness, the plan is to study a cohort of 65 children with Type I diabetes mellitus.
- Trial name
- NCT02218268
- Testing
- Pre-meal bolus, No meal bolus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cerebellar Diseases
Emotional Communication Disorders in Cerebellar Disease
The cerebellum has been linked to cognitive and emotional functions and there is increasing evidence that damage to posterior portions of the cerebellum can result in frontal-executive, visuospatial, and verbal deficits…
- Trial name
- NCT02106819
- Testing
- Testing of emotional communication ability, magnetic resonance imaging (MRI) of the brain
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Ischemic Stroke
Cough and Swallow Rehab Following Stroke
Stroke is the leading case of neurologic swallow dysfunction, or dysphagia. Post stroke dysphagia is associated with approximately 50% increase in the rate of pneumonia diagnoses; aspiration pneumonia is the most common…
- Trial name
- NCT01907321
- Testing
- Expiratory muscle strength training, Measures performed on all subjects, Pulmonary function test
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Gastrointestinal Symptoms, Gastrointestinal Transit Time
Potato Fiber and Gastrointestinal Function: Phase 3
The primary physiological impacts of fiber intake include the gastrointestinal effects of stool bulking, increased stool frequency and decreased gastrointestinal transit time (GTT).
- Conditions
- Gastrointestinal Symptoms, Gastrointestinal Transit Time, Stool Frequency
- Trial name
- NCT01964599
- Testing
- PF-RS, PF-RO1, PF-RO2
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Florida
Breast Neoplasms
Mobile Health (mHealth) Black Women With Breast Cancer
This research study will test whether a series of video clips with breast cancer information improves knowledge of breast cancer, breast cancer treatment and living with breast cancer.
- Trial name
- NCT02463474
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Alteration of Cognitive Function
Physiologic Effects of Topiramate on Cognition
Data generated from this pilot project will be used to support a larger, NIH funded study to investigate the physiologic mechanisms associated with the cognitive side effects of a commonly prescribed antiepileptic drug (AED)…
- Trial name
- NCT02884050
- Testing
- Topiramate
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
Tongue Motor Recruitment During Exercise
The prevalence of dysphagia may be as high as 22% in individuals over 50 years of age. There are few therapeutic options offered to these individuals.
- Trial name
- NCT02687737
- Testing
- Electromyography, Maximum expiratory pressure, Videofluoroscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Coronary Artery Disease
Pharmacological Effects of Crushing Prasugrel in STEMI Patients
Prasugrel has shown to be superior to clopidogrel, in adjunct to aspirin, in preventing recurrent ischemic events. Prasugrel is approved in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous…
- Trial name
- NCT02212028
- Testing
- prasugrel
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Florida
Vitamin D Deficiency (10 ng/mL to 30 ng/mL)
Vitamin D as a Supplement Against Falls in Elderly Study
The role of vitamin D deficiency on increased risk for falls and physical dysfunction is unclear. It is also unclear if taking vitamin D improves physical function and reduces fall risk in older adults.
- Trial name
- D-SAFE (NCT01827345)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida