Clinical trials: sponsored by University of Iowa
Sedentary, Overweight
Efficacy of a Combined Ergonomic Health Promotion Intervention on Employee Health
Our objective in this pilot study is to test the combined effect of a) replacing office workers' sedentary workstations with active workstations (LifeBalance Station) and b) optimizing computer workstation ergonomics on daily…
- Trial name
- NCT02071420
- Testing
- Active Workstation Intervention, Ergonomic Intervention, Email Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Tooth Loss, Peri-implant Mucosa Defect
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
The purpose of this non-inferiority trial is to determine the clinical efficacy of acellular dermal matrix (ADM) in the augmentation of the gum around dental implants as compared to an autologous gum graft (sCTG) obtained from…
- Trial name
- NCT02450383
- Testing
- Acellular Dermal Matrix, Autologous subepithelial connective tissue graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Respiratory Failure, Critical Illness
Sleep and Circadian Rhythms in Mechanically Ventilated Patients
This study examines the feasibility of assessing sleep and circadian rhythmicity in critically ill patients undergoing mechanical ventilation.
- Trial name
- NCT01276652
- Testing
- Environmental modification
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Iowa
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Atrophy of Edentulous Alveolar Ridge
Efficacy of Socket Grafting for Alveolar Ridge Preservation
The purpose of this study is to clinically and radiographically assess whether the use of a ridge preservation technique significantly minimizes alveolar ridge resorption following tooth extraction.
- Trial name
- NCT01794806
- Testing
- Tooth extraction and grafting with allograft, Tooth extraction
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cardiovascular Disease
Feasibility Study of Omega-3 Fatty Acids in Dialysis Patients
Cardiovascular disease and mortality is the largest comorbidity within the dialysis population. Nearly 50% of hemodialysis patients will have congestive heart failure at initiation.
- Trial name
- NCT01002118
- Testing
- Omega-3 Acid Ethyl Esters
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Iowa
Carcinoma, Non-Small-Cell Lung
Study to Evaluate Using Nelfinavir With Chemoradiation for Non-small Cell Lung Cancer
This study combines nelfinavir (NFV) with radiation therapy and chemotherapy as a treatment for non-small cell lung cancer (NSCLC) who are considered candidates for pre-operative treatment.
- Trial name
- NCT00791336
- Testing
- Nelfinavir
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Iowa
Conduct Disorder
Trial of Aripiprazole in the Treatment of CD in Adolescents
The proposed study will be a 6-week open label study evaluating aripiprazole in the treatment of 12 male post-pubertal adolescents (13-17 years, Tanner Stage 4) diagnosed with conduct disorder.
- Trial name
- NCT00250705
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Metastatic Melanoma
Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat
The purpose of this study is to treat metastatic melanoma with a combination of standard chemotherapy (decitabine and Temozolomide in a dose escalation scheme) with an study drug called panobinostat.
- Trial name
- NCT00925132
- Testing
- Temozolomide, Decitabine, Panobinostat
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Iowa
Sedation
Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients
The purpose of this study is to determine if intranasal ketamine is equally as effective and safe as intramuscular ketamine for procedural sedation in pediatric patients.
- Trial name
- NCT01170247
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Anesthesia
Ultrasound-image Guided Versus Doppler Guided Versus Palpation Technique for Arterial Cannulation in Adults
Radial arterial cannulation is a common invasive procedure for real-time measurement of arterial blood pressure. Placement of the arterial catheter using conventional palpation is often relatively easy and quick, but this is not…
- Trial name
- NCT01276171
- Testing
- Ultrasound, Doppler, Palpation
- Where
- United States
- Volunteers
- 749 people
- Sponsor
- University of Iowa
Newborn Infant
Temporal Artery Temperature Measurement in Neonates
The aim of this study was to evaluate the temporal artery thermometer by comparing temporal artery and axillary thermometer temperature measurements with rectal thermometer temperature measurements in neonatal patients.
- Trial name
- NCT02405429
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Multiple Myeloma
Tandem Auto Transplantation in Myeloma Patients With <12 Months of Prior Treatment
This study is designed to decrease toxicity associated with prior tandem transplant protocols by reducing the intensity of induction, consolidation and maintenance therapy, while increasing event-free survival by adding…
- Trial name
- NCT01548573
- Testing
- Dexamethasone, Tandem autologous stem cell transplant, Cisplatin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Iowa
Radial Artery Cannulation
Target Sign vs Palpation for Radial Arterial Line Placement
Invasive blood pressure monitoring is achieved by cannulating an artery and transducing the pressure. During arterial cannulation the artery can be located by palpation, but use of ultrasound has increased the success rate of…
- Trial name
- NCT02557828
- Testing
- arterial line placement
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hearing Loss
The Effect of Low-Level Laser Stimulation on Hearing Thresholds
The purpose of this study is to determine whether low-level laser therapy can improve hearing thresholds in individuals with hearing loss. Subjects will be randomly assigned to a treatment, placebo, or control group.
- Trial name
- NCT01820416
- Testing
- Low-level Laser Therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Iowa
Uncomplicated Bacterial Cystitis
A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department
Pilot study to compare the efficacy and safety of 3-day, twice-daily regimens of nitrofurantoin and ciprofloxacin in emergency department (ED) patients presenting with UBC.
- Trial name
- NCT01749605
- Testing
- Nitrofurantoin monohydrate/macrocrystals 100 mg BID x 3 days, ciprofloxacin 250 mg BID x 3 days
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Obesity, Vascular Diseases
Technique for Successful Ultrasound-guided Peripheral Vascular Access
Obtaining peripheral vascular access in medical patients is a necessary procedure for many healthcare providers. Peripheral vascular access is traditionally performed using palpation or visual inspection to identify appropriate…
- Trial name
- NCT01975974
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Pathological Gambling
Acamprosate in the Treatment of Pathological Gambling
The purpose of this study is to see whether acamprosate (Campral) will curb the desire to gamble in people with pathological gambling disorder.
- Trial name
- NCT00571103
- Testing
- acamprosate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Sedentary Lifestyle
MapTrek for Sedentary Workers
The aim of this study is to determine if participants randomized to our mHealth MapTrek game increases daily physical activity (average steps/day, active minutes/day) compared to a control group among sedentary office workers…
- Trial name
- NCT03109535
- Testing
- Fitbit + Maptrek, Fitbit only
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Astigmatism
Evaluation of the Bausch & Lomb PureVision Under Nighttime Driving Conditions
The objective of this study is to quantify differences in nighttime driving performance between the Bausch \& Lomb PureVision™ aspheric contact lenses and a conventional spherical contact lens.
- Trial name
- NCT00581659
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Iowa