Clinical trials: sponsored by University of Iowa
Sedentary Lifestyle
MapTrek for Sedentary Workers
The aim of this study is to determine if participants randomized to our mHealth MapTrek game increases daily physical activity (average steps/day, active minutes/day) compared to a control group among sedentary office workers…
- Trial name
- NCT03109535
- Testing
- Fitbit + Maptrek, Fitbit only
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Depression, Heart Failure
Combined Illness Management and Psychotherapy in Treating Depressed Elders
The purpose of this research study is to test a program developed to help patients with chronic heart or lung problems take care of themselves and cope with their illness or limitations.
- Conditions
- Depression, Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- COPE (NCT01337726)
- Testing
- Combined Psychotherapy and Illness Management, Illness Management Only
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- University of Iowa
Cleft Lip, Cleft Palate
Oral Cleft Prevention Program
The purpose of this study is to asses if taking 4 mg of folic acid per day at preconception and during the first three months of pregnancy decreases the risk of having a child with cleft lip and palate compared to 0.4 mg folic…
- Trial name
- NCT00397917
- Testing
- Folic acid: 4 mg versus 0.4 mg per day
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- University of Iowa
Tonsillitis
Celecoxib as a Post-tonsillectomy Pain Medication
The hypothesis is that celecoxib effectively reduces pain after a tonsillectomy and reduces post-operative narcotic use. To test this hypothesis, the study is placebo controlled (sugar pill).
- Trial name
- NCT00583453
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Iowa
Borderline Personality Disorder
Treatment for Borderline Personality Disorder
This study will expose patients to either a Systems Training for Emotional Predictability and Problem Solving (STEPPS) or treatment as usual (TAU) to determine the more effective therapy for treating borderline personality…
- Trial name
- NCT00055315
- Testing
- Systems Training for Emotional Predictability and Problem Solving (STEPPS), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- University of Iowa
Breast Cancer
Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment
The purpose of this research study is to understand effects of a complementary medicine therapy, Healing Touch on quality of life and immunity of patients who are receiving treatment for breast cancer.
- Trial name
- NCT00565305
- Testing
- Healing Touch, Standard Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Iowa
Pathological Gambling
Bupropion in the Treatment of Pathological Gambling
This study will determine whether the drug bupropion is an effective treatment for Pathological Gambling.
- Trial name
- NCT00055393
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Anesthesia
Pediatric Radial Arterial Cannulation
This prospective randomized study was designed to compare ultrasound guided technique with Doppler assisted technique for radial arterial cannulation in infant and small children.
- Trial name
- NCT01276158
- Testing
- Ultrasound, Doppler
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Iowa
Knee Osteoarthritis
Improving Walking in Older Adults With Knee Osteoarthritis
Knee osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults.
- Trial name
- NCT00583245
- Testing
- Gait Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Iowa
Relapsed Multiple Myeloma
ATRA, Celecoxib, and Itraconazole as Maintenance
The purpose of this study is to evaluate the safety and tolerability associated with the combination of ATRA/celecoxib/itraconazole as maintenance therapy given after an autologous stem cell transplant in relapsed multiple…
- Trial name
- NCT02401295
- Testing
- ATRA, Celecoxib, Itraconazole
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Iowa
Graft vs Host Disease
Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHD
The purpose of this study is to see whether serious graft versus host disease which is not well controlled with steroid treatment can be controlled with therapy with both daclizumab and infliximab.
- Trial name
- NCT00574470
- Testing
- daclizumab, infliximab
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Iowa
Acute Coronary Syndrome
Heart Rate Variability as a Predictor of Ischemic Heart Disease
Identification of patients who are at highest risk for heart attack is an important task for emergency medicine physicians. Currently, physicians use a variety of different scoring systems to stratify their risk for having a…
- Trial name
- NCT02959788
- Testing
- Heart rate variability
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Iowa
Chronic Lymphocytic Leukemia
A Dose Finding Study of CpG in Patients With Chronic Lymphocytic Leukemia Who Have Been Previously Treated
CpG has the potential to stimulate the immune system this study will evaluate the safety of CpG given sub-q or IV purpose is to measure biological changes in CLL cells after receiving CpG
- Trial name
- NCT00233506
- Testing
- CpG 7909
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Iowa
Anxiety Disorder, Fatigue
Effects of Healing Touch on Patients Undergoing Hematopoietic Stem Cell Transplant
This randomized pilot clinical trial studies healing touch or usual care in improving quality of life in patients undergoing stem cell transplant.
- Conditions
- Anxiety Disorder, Fatigue, Hematopoietic/Lymphoid Cancer, Pain
- Trial name
- NCT02194413
- Testing
- therapeutic touch, quality-of-life assessment, questionnaire administration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Iowa
Nasotracheal Intubation, Nasal Bleeding
Nasotracheal Intubation Over a Bougie
The purpose of this study is to determine whether nasal intubation over a bougie placed via a nasal trumpet will decrease nasal trauma when compared to the conventional technique of blind nasal endotracheal tube passage.
- Trial name
- NCT03003455
- Testing
- Nasotracheal intubation over a bougie, Conventional Nasotracheal Intubation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to improve quadriceps strength…
- Trial name
- PBFR2 (NCT01440972)
- Testing
- partial blood flow restriction (PBFR), low intensity resistance training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Primary Glioblastoma Multiforme
Gliadel Wafers and Temodar in the Treatment of Glioblastoma Multiforme
The purpose of this research study is to determine if combining all three treatments of Gliadel wafers, Temozolomide and Radiation therapy at the same time is safe and more effective than one treatment at a time.
- Trial name
- Temodar (NCT00574964)
- Testing
- Gliadel Wafer, Temodar and Radiotherapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Dense Deposit Disease
TP10 Use in Patients With C3 Glomerulopathy (C3G)
The purpose of this study is to evaluate the safety of repeated TP10 dosing in pediatric and adult patients with C3G and to evaluate the activity of TP10 in pediatric and adult patients with C3G, as measured by the proportion of…
- Trial name
- NCT02302755
- Testing
- TP10
- Where
- United States
- Sponsor
- University of Iowa
Low Cardiac Output
Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery
Measurement of the cardiac output is one of the important hemodynamic monitoring tools in cardiac surgery. It helps determine the type of medications needed to maintain optimal hemodynamic status in the entire perioperative…
- Trial name
- NCT02511457
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Iowa
Pregnancy
Study of Changes in the Feet With Pregnancy
This research is being conducted to determine whether use of an arch-supporting insole during pregnancy prevents alterations in foot structure and lower limb rotational movements.
- Trial name
- NCT01868074
- Testing
- Insole
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Iowa