Clinical trials: sponsored by University of Iowa
Spinal Injuries, Sarcoma
Spine and Tumor Screening and Supplementation
This project aims to evaluate an implementable screening tool and nutritional interventions that will lead to improved quality and patient safety.
- Conditions
- Spinal Injuries, Sarcoma, Nutritional Deficiency
- Trial name
- NCT03660540
- Testing
- Juven
- Where
- United States
- Sponsor
- University of Iowa
Quality of Life, Social Interaction
Music Therapy for Persons With Dementia
The purpose of this study is to examine the effectiveness of a specific, protocol-based group music therapy intervention, relative to a verbal discussion activity.
- Conditions
- Quality of Life, Social Interaction, Emotions, Mood
- Trial name
- NCT03643003
- Testing
- Music therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Iowa
Glioblastoma
Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)
This is a multi-institutional, consortium-based, non-interventional prospective blinded endpoints clinical study to determine whether high activity of Cytochrome C Oxidase (CcO) in tumor specimens from subjects with newly…
- Trial name
- NCT02997423
- Where
- 19 sites in United States
- Volunteers
- 153 people
- Sponsor
- University of Iowa
Neuroendocrine Tumors, Meningioma
Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)
This is a Phase 2 peptide receptor radionuclide therapy trial of 90Y-DOTATOC in patients with somatostatin receptor positive tumors.
- Conditions
- Neuroendocrine Tumors, Meningioma, Neuroblastoma, Medulloblastoma
- Trial name
- NCT03273712
- Testing
- 90Y-DOTA tyr3-Octreotide, 68Ga-DOTATOC PET Positron Emission Tomography (PET) whole body scan, Amino Acids
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Iowa
Multiple Sclerosis
tDCS and Glucose Uptake in Leg Muscles
This study is to examine the efficacy of tDCS to improving walking in people with Multiple Sclerosis (PwMS). Our study compromises 1 group of subjects with MS which will attend the lab for three sessions.
- Trial name
- NCT04016844
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Iowa
Infection
Use of Provodine to Protect HCW Hands (Aim II.1)
The investigators will assess whether applying Provodine, an FDA-approved hand hygiene product with a long duration of anti-microbial action, to healthcare workers' hands protects against self-contamination during the removal of…
- Trial name
- NCT03972826
- Testing
- Provodine
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Sepsis
TELEmedicine as an Intervention for Sepsis in Emergency Departments
Sepsis is a life-threatening condition that has doubled in incidence over the past decade, and timely aggressive medical intervention has been shown to save lives.
- Trial name
- TELEvISED (NCT04441944)
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 1,191 people
- Sponsor
- University of Iowa
Acute Ischemic Stroke, Ischemic Stroke
Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke
We will recruit men and non-pregnant women of any ethnic background between the age ≥ 18 and ≤ 90 years that have acute ischemic stroke and underwent Mechanical Thrombectomy (MT) with TICI 2b or 2b following MT.
- Trial name
- iTREMT (NCT04818944)
- Testing
- Tirofiban Hydrochloride
- Where
- United States
- Sponsor
- University of Iowa
Multiple Sclerosis
tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple Sclerosis
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) on neuropathic pain and fatigue in people with MS. The investigators will conduct tDCS or sham on 5 consecutive days.
- Trial name
- NCT03870048
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Iowa
Foot Injuries and Disorders
SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry
Orthotists currently use a range of weight bearing conditions when casting or scanning a patient's limb during the Ankle foot orthosis (AFO) fitting process.
- Trial name
- NCT04600102
- Testing
- Structure Sensor
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Parkinson Disease, Healthy Adult
Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease
Parkinson's disease (PD) affects approximately 1 million people in the US, with annual health care costs approaching $11 billion. PD results from a loss of dopamine-producing cells in the brain.
- Trial name
- NCT04762823
- Testing
- Cerebellar transcranial direct current stimulation at 4 mA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Tooth Loss
Harnessing Chronomodulation to Enhance Osteogenesis
Chronotherapy is an emerging field in biomedicine that leverages on fine-tuning the timing of drug delivery to obtain a therapeutic effect. Dr.
- Trial name
- NCT03911336
- Testing
- Group A - test:Tooth extraction and intake of NSAID and a non-NSAID, Group B - Control 1: tooth extraction and intake of NSAID and a non-NSAID, Group C - Control 2: tooth extraction and intake of a Non-Nsaid
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Depression
Optimizing Fidelity of Interpersonal Psychotherapy
The study is designed to develop and validate an instrument to measure quality and adherence to IPT for research and training purposes. The measure is now being used to evaluate training in IPT.
- Trial name
- NCT03053765
- Testing
- training in IPT
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Depressive Symptoms
Effective Implementation of Interpersonal Psychotherapy
The study is designed to observe the impact of improved measures of the fidelity on the community delivery of Interpersonal Psychotherapy.
- Trial name
- NCT03170908
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Iowa
Child Behavior Disorders, Implementation Science
Pre-Implementation Enhancement Strategy To Improve Teachers' Intention to Implement Evidence-Based Practices
Background: As the most common setting where youth access behavioral health services, the education sector frequently employs training and follow-up consultation as cornerstone implementation strategies to promote the uptake and…
- Conditions
- Child Behavior Disorders, Implementation Science, Adolescent Problem Behavior at School, Healthcare Providers
- Trial name
- SC-PIES (NCT05240222)
- Testing
- Pre-implementation enhancement strategies (SC-PIES)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dental Caries on Pit and Fissure Surface
A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants
The purpose of this split-mouth, randomized, controlled trial is to evaluate the retention rates of sealants placed under Isolite vs. cotton roll isolation.
- Trial name
- NCT02668874
- Testing
- Isolite System, Cotton Roll Technique
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hearing Loss, Unilateral, Hearing Loss, Profound
Iowa Cochlear Implant Clinical Research Center Study of SSD Using Med-El Cochlear Implants
The purpose of this study is to understand the speech perception in noise and in quiet and localization benefits in a laboratory setting in listeners that receive a cochlear implant in an ear with severe to profound hearing loss…
- Trial name
- NCT03929809
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Iowa
Multiple Sclerosis
Cerebral Blood Flow and tDCS
With this study, the investigators will substantiate if regional cerebral blood flow (CBF) is affected by tDCS, assess the amount of CBF change in relation to different currents, and measure differences in regional CBF under…
- Trial name
- NCT04033133
- Testing
- tDCS
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hearing Loss, Hearing Disorders
Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe)
The purpose of this project is to validate a quick, easy-to-use and administer smartphone hearing-in-noise test. The Hearing-in-Noise Test (HINT) measures an individual's ability to hear speech in quiet and in noise.
- Conditions
- Hearing Loss, Hearing Disorders, Hearing Abnormality, Hearing Disability
- Trial name
- HearMe (NCT03429777)
- Testing
- HearMe Smartphone Application
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Healthy
Micropore Closure Kinetics at Various Body Sites
The study to be performed will define the rate of skin barrier recovery following micropatch application to the skin on the upper arm, volar forearm, and abdomen in healthy subjects.
- Trial name
- NCT03657277
- Testing
- Micropatch
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Iowa