Clinical trials: sponsored by University of Manchester
Scleroderma, Systemic, Ulcer
Light Treatment for Scleroderma Finger Ulcers
Digital (finger) ulcers are common in patients with systemic sclerosis (SSc) and causes much pain and affects how patients use their hands.
- Trial name
- DULight (NCT02472743)
- Testing
- Custom-built phototherapy lamp
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Manchester
Skin Cancer
The Effect of Green Tea and Vitamin C on Skin Health
There is little information on the effect of oral bioactive compounds on human skin clinically despite evidence of a beneficial effect from laboratory studies.
- Trial name
- NCT01032031
- Testing
- Green tea + vitamin C high dose
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Pancreas Transplantation
GDT Vs ST for Pancreas Transplant Surgery
A Pancreas Transplant is the accepted treatment in patients with Insulin Dependent Diabetes Mellitus (IDDM) and end-organ failure. Simultaneous Pancreas and Kidney (SPK) Transplant is done in over 90% of cases.
- Trial name
- NCT01619904
- Testing
- Goal-Directed Therapy, Standard Therapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Manchester
Smoking Cessation
Trial of the Smoking Cessation Volitional Help Sheet in Primary Care
The study will recruit patients who smoke from a general practice clinic and randomize them either to: (1) form implementation intentions by linking in memory situations in which they are tempted to smoke with strategies to avoid…
- Trial name
- NCT02454621
- Testing
- Volitional help sheet
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manchester
Diabetes
Wound Healing Process in Diabetic Neuropathy and Diabetic Neuroischemia
Diabetes mellitus is one of the leading causes of illness worldwide. Diabetes can affect nerves, skin and blood vessels. Diabetics with problems in their nerves can lose the sense of touch in their feet (called neuropathy) and so…
- Trial name
- Geko (NCT02378909)
- Testing
- Electrical stimulation device.
- Volunteers
- 60 people
- Sponsor
- University of Manchester
Healthy Volunteers
Sunlight Exposure and Vitamin D Status of Children of South Asian Ethnicity Living in the UK
The purpose of this study is to examine the amount of sunlight exposure and vitamin D status of adolescent schoolchildren of South Asian ethnicity in each season throughout the year.
- Trial name
- NCT01623414
- Where
- United Kingdom
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Mental Health Wellness 1, Depression
Randomised Controlled Trial of Method of Levels Cognitive Therapy
The purpose of this study is to determine whether Method of Levels Cognitive Therapy is an effective intervention for treating clients with a range of presenting problems in primary care by comparing it with a waiting list…
- Conditions
- Mental Health Wellness 1, Depression, Anxiety
- Trial name
- NCT01554150
- Testing
- Method of Levels Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Manchester
Retinal Ageing
Carotenoid Supplementation and Normal Ocular Health
Normal ageing affects vision as a result of preretinal and retinal changes. Photoreceptors, the light sensitive cells in the retina, degenerate and the rods (responsible for night vision) are most susceptible to damage with…
- Trial name
- NCT02147171
- Testing
- VisionAce
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Kidney Transplantation, Pancreas Transplantation
CEUS in Kidney and Pancreas Transplantation
This study is to investigate whether it is possible to use a special type of ultrasound scan (CEUS, Contrast Enhanced Ultrasound Scan) to view the shape, assess blood supply and calculate the amount of oxygen being carried to a…
- Trial name
- NCT02104024
- Testing
- Contrast Enhanced Ultrasound Scanning
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- University of Manchester
Anxiety Disorder, Breast Cancer
Acupuncture or Self-Acupuncture in Managing Cancer-Related Fatigue in Women Who Have Received Chemotherapy for Stage I, Stage II, or Stage IIIA Breast Cancer
RATIONALE: Acupuncture may help relieve fatigue caused by breast cancer. It is not yet known whether acupuncture is more effective than self-acupuncture in managing fatigue in women with breast cancer.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00957112
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United Kingdom
- Volunteers
- 320 people
- Sponsor
- University of Manchester
Anxiety Disorder, Depression
Study of How Caregivers Help Patients Cope With Respiratory and Other Symptoms Caused by Lung Cancer
RATIONALE: Gathering information about how patients, caregivers, and healthcare professionals cope with symptoms caused by lung cancer, such as breathlessness, cough, fatigue, anxiety, depression, pain, and difficulty sleeping…
- Conditions
- Anxiety Disorder, Depression, Dyspnea, Fatigue
- Trial name
- NCT00979888
- Testing
- educational intervention, informational intervention, psychosocial support for caregiver
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Manchester
Anxiety Disorder, Nausea and Vomiting
Acupressure Wristbands or Standard Care in Controlling Nausea Caused by Chemotherapy
RATIONALE: Acupressure wristbands may prevent or reduce nausea caused by chemotherapy. It is not yet known whether acupressure wristbands are more effective than standard care in controlling acute and delayed nausea.
- Conditions
- Anxiety Disorder, Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00978185
- Testing
- medical chart review, questionnaire administration, acupressure therapy
- Where
- United Kingdom
- Volunteers
- 699 people
- Sponsor
- University of Manchester
Skin Cancer
An Immunonutritional Approach to the Prevention of Skin Cancer
Skin cancer incidence continues to rise and ultraviolet radiation (UVR) in sunlight is the principal cause. Solar UVR can promote cancer development through its ability to suppress the immune system.
- Trial name
- NCT01032343
- Testing
- Omega-3 PUFA, Gelatine
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cough, Healthy Controls
Neurophysiology of Cough Reflex Hypersensitivity
Central sensitisation is an increase in the excitability of nerves within the central nervous system, which can lead to heightened sensitivity to certain stimuli. This process is involved in some chronic pain conditions e.g.
- Trial name
- NOTCH (NCT00977366)
- Testing
- Hydrochloric acid (0.15 molar), Saline
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Child Behavioural and Emotional Difficulties, Parenting Practices
Trial of a Parenting Discussion Group in Panama, Central America
The present study aims to examine the effectiveness of a parenting intervention, the Triple P Positive Parenting Program Level 3 discussion groups "dealing with disobedience".
- Trial name
- NCT01771068
- Testing
- Triple P Positive Parenting Program Discussion Group "Dealing with Disobedience"
- Where
- Panama
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Healthy Schoolchildren
Sunlight Exposure and Vitamin D in Children
The purpose of this study is to examine the amount of sunlight exposure and vitamin D status of adolescent schoolchildren in each season throughout the year.
- Trial name
- NCT01477827
- Testing
- None - observational study
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Stroke
ACT NoW: Assessing the Effectiveness of Communication Therapy in the North West
Assessing Communication Therapy in the North West (ACT NoW) is a research project which aims to evaluate the effectiveness, cost effectiveness and service user preferences for communication therapy following stroke when compared…
- Trial name
- ACT NoW (NCT00831740)
- Testing
- Speech and Language Therapy (SLT), Attention Control
- Where
- United Kingdom
- Volunteers
- 170 people
- Sponsor
- University of Manchester
Diabetes, Hypoglycemia
Sitagliptin Versus Sulphonylurea in Type 2 Diabetes During Ramadan
This study will assess if Sitagliptin addition to metformin or glitazone is better than current sulphonylurea based treatments during Ramadan.
- Trial name
- NCT00766441
- Testing
- Sitagliptin, sulphonylurea
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Manchester
Postoperative Pain, Wisdom Tooth
Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
The purpose of this study is to investigate whether robust analgesic regime (protective analgesia) can improve postoperative pain experience for patients undergoing lower wisdom teeth extraction under day case general anaesthetic.
- Trial name
- NCT00895843
- Testing
- Brufen retard, ibuprofen, Bupivacaine
- Where
- 2 sites in United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Low Back Pain
Effects of a Mulligan Mobilisation in the Lumbar Flexion Range of Asymptomatic Subjects
Mulligan's mobilisation techniques are believed to increase the range of movement (ROM) in patients with low back pain. The primary aim of this study was to investigate the mechanical effects of Mulligan's "SNAG" technique on…
- Trial name
- Mulligan (NCT00678093)
- Testing
- Application of the SNAG technique
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Manchester