Clinical trials: sponsored by University of Manchester
Self Injurious Behaviour
Skin Camouflage for Women Prisoners With Self-Harm Scarring
Women prisoners are more likely to commit suicide or self-harm than women in the community or male prisoners. Healthcare services have improved how they manage self-harm in the community and prisons.
- Trial name
- COVER (NCT02638974)
- Testing
- Medical Skin Camouflage
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University of Manchester
Stillbirth
The Midlands and North of England Stillbirth Study
The United Kingdom has one of the highest rates of stillbirth in Europe, with more than 4,000 stillbirths every year; which equates to more than 11 deaths every day.
- Trial name
- MiNESS (NCT02025530)
- Testing
- Questionnaire
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,030 people
- Sponsor
- University of Manchester
Psychological
Service-user Experiences of Text-based Conversations With a Computer About Their Difficulties
Mental health problems such as anxiety and depression are common. Services are finding it difficult to treat people quickly. This has led to computers being used to treat common problems.
- Trial name
- NCT03524196
- Testing
- Manage Your Life Online (MYLO)
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Manchester
Rectal Adenocarcinoma
Optimisation of Radiotherapy in Rectal Cancer (ORREC)
This is a retrospective study using images acquired routinely for diagnosis of rectal cancer to see if these could be used to predict responses to radiotherapy treatment and if it can, whether the treatment can be optimised to…
- Trial name
- ORREC (NCT04090450)
- Testing
- chemo-radiotherapy
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- University of Manchester
Suicide
The INSPiRe Programme: Developing an Intensive Suicide Prevention Therapy for Suicidal Prisoners
This study aims to assess the acceptability and feasibility of a short-term, intensive Cognitive Behavioural Therapy (CBT) delivered to male prisoners who have thoughts of ending their lives.
- Trial name
- NCT03499548
- Testing
- INSPiRe Programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Manchester
Psychosis
Method of Level (MOL) Therapy for Psychosis
The study is a systematic case replication series of a new psychological therapy Method of Levels (MOL) for people who experience psychosis. Between 6 and 8 people with psychosis who receive services from CMHT will be recruited.
- Trial name
- NCT04038112
- Testing
- psychological therapy Method of Levels (MOL)
- Volunteers
- 6 people
- Sponsor
- University of Manchester
Written Information, Written Info and Hearing Aid Reminder
A Self-management Intervention for Adult Patients With Hearing Difficulties to Promote Hearing Aid Use and Benefit
The aim of the present study is to test I-PLAN as a self-management tool to promote hearing aid use and benefit (measured by self-reported questionnaires and hearing aid data-logging) among new adult hearing aid patients via a…
- Conditions
- Written Information, Written Info and Hearing Aid Reminder, Written Info and Planning on Hearing Aid Use, All Materials
- Trial name
- NCT03742609
- Testing
- ii) the reminder, ii) written behavioural plan, iv) all materials
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Hearing Aid
Controlled Trial of the I-PLAN Intervention
That is a need for intervention to promote hearing aid use among adult patients with hearing aids. The aim of the present study was, for the first time, to evaluate the efficacy of the I-PLAN intervention to promote hearing aid…
- Trial name
- NCT04017416
- Testing
- I-PLAN
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- University of Manchester
Psychosis, Medication Adherence
Piloting MOL Intervention for Neuroleptic Decision Making
The aim of the current study is to pilot a novel intervention to help people explore their decision making around the use of neuroleptic medication.
- Trial name
- NCT03537040
- Testing
- Method of Levels
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Neurofibromatosis 1
Non-invasive Stimulation in Neurofibromatosis Type 1
Intellectual impairments are a significant cause of morbidity in children with birth defects along with long term implication on academic and occupational functioning.
- Trial name
- tDCS is NF1 (NCT03310996)
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Manchester
Social Anxiety Disorder, Social Anxiety
Metacognitive Therapy for Social Anxiety in Youth
Social anxiety disorder (SAD) is a fear of social situations that involve interacting with other people. Although it can be very upsetting, there are ways to help people deal with it.
- Conditions
- Social Anxiety Disorder, Social Anxiety, Social Phobia
- Trial name
- NCT03514225
- Testing
- Metacognitive Therapy for Social Anxiety
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Schizophrenia and Disorders With Psychotic Features
The Benefit of Minocycline on Negative Symptoms in Schizophrenia: Extent and Mechanisms
The purpose of this study is to investigate if minocycline limits the development of negative symptoms in early psychosis and to test via what mechanism of action this change occurs.
- Trial name
- BeneMin (NCT02928965)
- Testing
- Minocycline
- Volunteers
- 207 people
- Sponsor
- University of Manchester
Mental Health Wellness 1, Anxiety
Enhancing One's Sense of Self Using Self-Affirmation
This study evaluates whether a brief psychological intervention, known as a self-affirmation intervention which works by allowing one to recognise their own value, can improve well-being.
- Conditions
- Mental Health Wellness 1, Anxiety, Self Esteem
- Trial name
- NCT03849924
- Testing
- Self-affirmation
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Obesity
Effects of Sweetness on Neurocognitive Responses, Glycemia and Food Intake
This study aims to examine potential differences in neurocognitive responses to food-related cues, physiological and appetite responses as well as subsequent energy intake following the consumption of preloads differing in…
- Trial name
- NCT03711084
- Testing
- Natural high potency sweetener from leaf extract, Glucose, Sucrose
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Speech Sound Disorder
Sharing Books With Children
The promotion of language and communicative development in the early years is extremely important. Children who enter school with good language skills have better educational and economic success.
- Trial name
- NCT03006744
- Testing
- Phonological awareness training, Reading enjoyment training
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manchester
Stillbirth
Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study
The study is a multicentre evaluation of maternity care delivered through the Saving Babies' Lives care bundle using both quantitative and qualitative methodologies.
- Trial name
- SPiRE (NCT03231007)
- Testing
- Questionnaire
- Where
- 20 sites in United Kingdom
- Volunteers
- 4,952 people
- Sponsor
- University of Manchester
Colorectal Cancer, Liver Metastasis Colon Cancer
The CLiFF Study: Change in Liver Function and Fat in Pre-operative Chemotherapy for Colorectal Liver Metastases
The CLiFF Study will assess changes in liver function and liver fat in patients with colorectal liver metastases (CLM) undergoing pre-operative chemotherapy before liver resection.
- Conditions
- Colorectal Cancer, Liver Metastasis Colon Cancer, Chemotherapy Effect, Obesity
- Trial name
- CLiFF (NCT03562234)
- Testing
- MR, LiMAx
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Manchester
Overweight
Using Implementation Intentions to Self-incentivise Weight-loss
The aim of the present research is to test the effect of helping people to reward themselves when they have successfully lost weight and the impact this will have on subsequent weight.
- Trial name
- NCT03522727
- Testing
- Single self-incentivising implementation intention, Multiple self-incentivising implementation intentions, Self-generated self-incentivising implementation intentions
- Where
- 2 sites in United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Aortic Aneurysm, Abdominal
The AAA Get Fit Trial: A Pilot Randomised Controlled Trial of Community Based Exercise in Patients With Abdominal Aortic Aneurysms
Rupture of abdominal aortic aneurysms(AAA) causes 12,000 deaths/year in the UK.1 Elective repair to prevent this carries a perioperative mortality of 4.5% for open surgery and 1% for endovascular repair.
- Trial name
- NCT02997618
- Testing
- Community based exercise programme, Control
- Volunteers
- 58 people
- Sponsor
- University of Manchester
Peripheral Arterial Disease, Cardiovascular Diseases
The RESPECT-PAD Trial
Peripheral arterial disease affects around 25% of the UK population aged over 55. Left untreated it can lead to debilitating pain, gangrene, amputation and death.
- Trial name
- NCT03298230
- Testing
- REmotely SuPervised Exercise Training, Supervised Exercise Training
- Volunteers
- 60 people
- Sponsor
- University of Manchester