Clinical trials: sponsored by University of Manchester
Family Caregivers
Supporting Family Carers to People Living With Symptoms of Dementia at Home up to the End of Life
This is a qualitative study that will seek to gain further understanding of the support needs of family carers to people living with symptoms of dementia up to the end of life.
- Trial name
- NCT03666611
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Psychosis
Cognitive Remediation for First Episode of Psychosis Patients
This study aims to look at the effectiveness of a combination of cognitive remediation and social cognition training to improve cognition and functioning when compared to cognitive remediation alone.
- Trial name
- NCT01967420
- Testing
- Cognitive remediation, Social cognition training
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Manchester
Health Behaviour
Evaluating Specific Plans to Increase Smoking Quit Attempts in Prison
Tobacco use is the greatest cause of ill health and early mortality, and smoking is the main contributor to around 75,000 deaths a year in England.
- Trial name
- NCT02567097
- Testing
- Self-Incentive
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Major Depression (in Remission)
Investigating the Mechanisms of Mindfulness-based Cognitive Therapy (MBCT)
This research will investigate the neuropsychological mechanisms underlying the eight-week Mindfulness-based Cognitive Therapy (MBCT) programme.
- Trial name
- NCT02226042
- Testing
- Mindfulness-based Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Glaucoma, Diagnostic Self-evaluation
Development and Evaluation of a Self-administered/Assisted Visual Field Screening Tool for Glaucoma
This project aims to evaluate a self-administered screening test for glaucoma, the second largest cause of blindness in the western world.
- Trial name
- NCT02162043
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Smoking Cessation
Testing Familial Self-affirmation for Smoking Cessation
Evidence suggests that affirming the self can help people to make changes in their health behavior. Typically, people affirm a personally-important value, but evidence suggests that affirming the values of family ("familial…
- Trial name
- NCT03295409
- Testing
- Self-affirmation
- Where
- 2 sites in Hong Kong
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Fetal Distress, Fetal Heart Rate Disorder Nos
A Mixed Methods Study to Explore the Feasibility of a Novel Continuous Fetal Monitoring Device
A stillbirth describes when a baby dies after 24 weeks of pregnancy and before being born. In the UK there are roughly 9 stillbirths every day.
- Trial name
- NCT03370822
- Testing
- MONICA AN24 device
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Manchester
Accidental Falls
Cluster RCT of Falls Prevention Exergames for Older Adults
This cluster RCT study will investigate the effectiveness of strength/balance Exergames (exercise and computer games that use body movements as controls) developed to improve balance, function, prevent falls and increase exercise…
- Trial name
- Profexs (NCT02634736)
- Testing
- Exergame plus usual treatment
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Photoaging
Efficacy in Daily Use of a Novel Skin Care Product for the Treatment of Photoaged Skin
Photoaged or chronically sun-exposed skin is characterised by a number of clinical features including fine and coarse wrinkles. The pathogenesis of wrinkle formation has yet to be determined fully but recent work suggests that…
- Trial name
- NCT03144193
- Testing
- Topical anti-aging cosmetic cream
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Mental
Sleep Intervention
A trial that tests whether implementation intentions improve sleep among adoelescents.
- Trial name
- NCT03047356
- Testing
- "If-then" plans, Control
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Hypochondriasis
Metacognitive Therapy for Health Anxiety
The study involves a comparing a new psychological treatment- Metacognitive Therapy (MCT) which has shown promising results in the treatment of health anxiety to no treatment at all- a waiting list.
- Trial name
- NCT02404116
- Testing
- Metacognitive Therapy, Wait List
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Healthy Volunteers, Schizophrenia
Effects of Ketamine and Risperidone on Cognition
The primary objective of this study is: To determine the effects of ketamine, which blocks the ion-channel gated by the NMDA receptor, on performance of cognitive tasks and the extent to which these effects can be reversed by the…
- Trial name
- Schiz_2 (NCT01140620)
- Testing
- ketamine, risperidone, saline
- Where
- 3 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Attention Deficit Hyperactivity Disorder
The Feasibility of a Brief Attention Training Technique in Improving Behaviour and Attention in Children With ADHD
This study aims to investigate the application of the Attention Training Technique in children with ADHD aged 7-11 years old. The research aims to investigate both the feasibility of this technique in this population as well as…
- Trial name
- NCT02516917
- Testing
- Attention Training Technique
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Manchester
Cancer
Triple P for Parents of Children With a Diagnosis of Cancer
The purpose of the study is to assess the characteristics of parents who enroll in parenting interventions and to assess the utility and efficacy of a self-directed Triple-P intervention for parents of children with a diagnosis…
- Trial name
- NCT02647684
- Testing
- Self-Directed Triple P
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Manchester
Generalized Anxiety Disorder
A Feasibility Study of Group Metacognitive Therapy Versus Mindfulness Meditation Therapy
The study will examine the effectiveness of group metacognitive therapy in comparison with group meditation therapy, in patients with Generalised Anxiety Disorder.
- Trial name
- MCT (NCT02096484)
- Testing
- Group Metacognitive Therapy, Mindfulness Meditation Therapy
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Manchester
Schizophrenia, Spectrum
Self Directed Positive Parenting Program (Triple P) for Psychosis: A Clinical Case Series
The aim of the case series study is to explore if a self directed version of the Positive Parenting Program (Triple P) is a feasible and acceptable intervention for individuals with psychosis who are parents.
- Conditions
- Schizophrenia, Spectrum, Disorders
- Trial name
- NCT02199704
- Testing
- Self Directed Positive Parenting Program
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Manchester
Macular Degeneration, Age-Related Macular Degeneration
Development of a Device to Measure Dark Adaptation
Age Related Macular Disease (AMD) is easily the leading cause of blindness in older people in developed countries. It affects between 30 and 50 million individuals worldwide, with around 30% of the over 65's showing early signs…
- Trial name
- NCT02090751
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Intrabony Periodontal Defects
Using MIST With or Without EMD in Treatment of Intrabony Periodontal Defects.
After performing the power calculation, healthy adult participants for the study will be randomly allocated into two groups. The intervention group will receive minimally invasive surgical techniques (MIST) with enamel matrix…
- Trial name
- NCT02810054
- Testing
- Minimally Invasive Surgical Techniques (MIST), Enamel Matrix Derivative (EMD)
- Volunteers
- 30 people
- Sponsor
- University of Manchester
Parenting, Psychosis
Understanding and Helping Families: Parents With Psychosis
The purpose of this trial is to explore parent-child interactions in parents with and without psychosis, and ascertain whether a brief (10 week) supported self-help parenting program offered to parents in their own homes can help…
- Conditions
- Parenting, Psychosis, Schizophrenia
- Trial name
- NCT02622048
- Testing
- Triple P Positive Parenting Programme
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Early Diffuse Cutaneous Systemic Sclerosis
Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
The aim of the study is to compare the effectiveness of commonly used immunosuppressant treatments for early diffuse cutaneous systemic sclerosis (SSc).
- Trial name
- ESOS (NCT02339441)
- Testing
- Methotrexate, Mycophenolate mofetil, Cyclophosphamide
- Volunteers
- 320 people
- Sponsor
- University of Manchester