Clinical trials: sponsored by University of Manitoba
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba
Vasectomy, Contraception
Utility of ChatGPT in Pre-vasectomy Counselling in an Office-based Setting
The investigators wish to perform a pilot study at the Manitoba Men's Health Clinic to assess if pre-vasectomy counseling with ChatGPT can safely streamline the consultation process by reducing visit times, while increasing…
- Trial name
- NCT06009783
- Testing
- ChatGPT Language Model
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Post-operative Delirium
EEG Guidance of Anesthesia (ENGAGES-CANADA)
This study examines the potential link between deep levels of anesthesia and delirium.
- Trial name
- ENGAGES (NCT02692300)
- Testing
- EEG-Guided Group
- Where
- Canada
- Volunteers
- 1,225 people
- Sponsor
- University of Manitoba
Odontogenic Infection of Jaw (Disorder)
The Prospective Evaluation of Peri-Operative Glucocorticoid Use in the Management of Cervicofacial Infections of Odontogenic Origin
This study is a clinical trial. In Manitoba, the treatment of cervicofacial infections of odontogenic origin which require inpatient medical and surgical management by Oral and Maxillofacial Surgeons are treated in a reproducible…
- Trial name
- NCT05951504
- Testing
- Methylprednisolone
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- University of Manitoba
Healthy
The Anabolic and Catabolic Effect of Loaded and Unloaded Exercise on Articular Cartilage Health
The serum concentration of cartilage oligomeric matrix protein (sCOMP) has been considered a mechano-sensitive biomarker of articular cartilage turnover, and N-propeptide of type II collagen (PIIANP) is a proposed biomarker of…
- Trial name
- NCT05925244
- Testing
- Control Condition, +12% Body Mass, -12% Body Mass
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Concussion, Mild
Omega-3 Treatment for Concussion in Adolescents
The goal of this clinical trial is to test omega-3 fatty acid supplementation as a treatment in adolescents with a concussion. The main questions it aims to answer are: Does supplementing with omega-3 fatty acids improve time to…
- Trial name
- CONCUSS (NCT05847608)
- Testing
- Omega-3
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Manitoba
Cerebral Palsy
Use of Transcranial Magnetic Stimulation and Constraint Induced Movement Therapy in Pediatric Unilateral Cerebral Palsy
Cerebral Palsy (CP) is the most common cause of childhood physical disability. Early CP diagnosis and intervention are crucial to improving outcomes in these patients.
- Trial name
- NCT04902521
- Testing
- Transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Body Surface Cooling Methods
Cooling During Exercise in the Heat
The goal of this clinical trial is to compare the effectiveness of upper-body surface cooling with whole-body surface cooling on exercise performance while wearing firefighter clothing in the heat.
- Trial name
- NCT05890261
- Testing
- Cold water-perfused cooling garment
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
SARS-CoV Infection, Covid19
The CHILD Cohort COVID-19 Add-On Study
The objective of this study is to determine the prevalence and transmission of SARS-CoV-2 infection among Canadian children and parents in the CHILD cohort, identify predictors of infection susceptibility and severity, and…
- Trial name
- NCT05234359
- Testing
- Serology Testing, Stool sample
- Where
- Canada
- Volunteers
- 5,385 people
- Sponsor
- University of Manitoba
Inflammatory Bowel Diseases, Anxiety
Internet-Based Cognitive Behavioural Program for Managing Stress With IBD: An RCT
The study will examine the efficacy of an internet-based cognitive behavioural therapy (iCBT) for Inflammatory Bowel Disease (IBD) intervention to reduce stress, anxiety, and depression in individuals with IBD and comorbid…
- Conditions
- Inflammatory Bowel Diseases, Anxiety, Depression, Stress
- Trial name
- iCBT (NCT04700917)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 352 people
- Sponsor
- University of Manitoba
Amblyopia
Visual Functional Connectivity and Visual Improvement After TMS/Binocular Treatment
The purpose of this study is to assess the effectiveness of combining binocular treatment with repetitive transcranial magnetic stimulation (rTMS) in improving the vision of adults with amblyopia.
- Trial name
- NCT03151200
- Testing
- Computer based binocular treatment, Transcranial magnetic stimulation
- Where
- Canada
- Sponsor
- University of Manitoba
Depression, Anxiety
Building Emotion Awareness and Mental Health (BEAM): Mothers of Toddlers
During the COVID-19 pandemic, the prevalence of maternal depression and anxiety has increased and research suggests that the cognitive development of children born during the pandemic has been impacted.
- Trial name
- NCT05306626
- Testing
- Building Emotion Awareness and Mental Health (BEAM)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Manitoba
Functional Neurological Disorder
Behavioural and Electrophysiological Effects of rTMS in Functional Neurological Disorders
The purpose of this study is to better understand Functional Neurological Disorders (FND) by measuring movement timing and brain activity in patients with FND during deliberate movements and when expressing an 'intention' to…
- Trial name
- NCT04942600
- Testing
- MagStim Rapid2 Transcranial Magnetic Simulation
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Manitoba
Diabetes Prevention, Obesity Prevention
Acute Food INtake Effect of Hemp Protein (A FINEH Protein) Trial - Part 2
The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2)…
- Trial name
- NCT02458027
- Testing
- Hemp Shake, Hemp, Soybean Shake
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diabetes, Cardiovascular Diseases
The Manitoba Personalized Lifestyle Research (TMPLR) Study
Lifestyle factors, such as diet, physical activity and sleep, are associated with the development of many chronic diseases. The objective of The Manitoba Personalized Lifestyle Research (TMPLR) study is to understand how these…
- Conditions
- Diabetes, Cardiovascular Diseases, Chronic Kidney Diseases
- Trial name
- NCT03674957
- Where
- Canada
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Depression, Anxiety
Building Emotion Awareness and Mental Health (BEAM): Community Partnership With Family Dynamics
Throughout the COVID-19 pandemic, postpartum depression and anxiety has increased dramatically. This is problematic as mothers in Manitoba must wait 12-18 months for therapeutic services.
- Trial name
- NCT05398107
- Testing
- Experimental: Building Emotion Awareness and Mental Health (BEAM), Control: MoodMission
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Hypercholesterolemia
Validating the "Foods for Health" Portfolio of Functional Food Products
The objective of this research project is to investigate the ability to affect cardiovascular disease (CVD) risk factors through a novel, easily implemented functional food-based approach.
- Trial name
- NCT02341924
- Testing
- Portfolio of functional foods, Control foods
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy Ageing
Use of Coconut Nourish and Queen Garnet Plum to Improve Health in an Elderly Population
The purpose of this study is to identify whether the combination of coconut Nourish and Queen Garnet plum are able to attenuate ageing-related complications, including muscle mass loss and inflammation.
- Trial name
- NCT03594097
- Testing
- Treatment cookies, Control cookies
- Where
- 2 sites in Australia, Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Disease, Diabetes
Canola Oil Multi-Centre Intervention Trial II
The objectives of the study are to examine the health benefits of dietary canola oils on body composition, specifically on android fat, and weight management.
- Conditions
- Cardiovascular Disease, Diabetes, Metabolic Syndrome
- Trial name
- COMIT2 (NCT02029833)
- Testing
- Regular Canola Oil, High Oleic Canola Oil, Western Type Diet - Common Dietary Oils
- Where
- 4 sites in United States, Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Metabolic Syndrome
Canola Oil, Fibre and DHA Enhanced Clinical Trial
The purpose of this study is to examine the effects of consumption of a novel food supplement consisting of Canola Oil, Fibre and DHA, containing the most effective food bioactives, including n-3 fatty acid enriched dietary oil…
- Trial name
- NCT02091583
- Testing
- Butter, sunflower and safflower oil, High Oleic Canola Oil and DHA (HOCO-DHA), Barley beta-glucan
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba