Clinical trials: sponsored by University of Manitoba
Motivational Interviewing
MI for Physical Activity Among Older Adults
The purpose of this study is to determine the feasibility of VIrtual Motivational INTerviewing (VIMINT) to promote physical activity levels among older adults; post-intervention and at two-month follow-up.
- Trial name
- NCT05179148
- Testing
- Motivational Interviewing
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Lung Cancer
Excretion of Acetylamantadine (AA) by Lung Cancer Patients During a Chemotherapy Regimen
This study is designed to determine if changes in acetyl amantadine (AA) metabolism with systemic chemotherapy - reflective of SSAT1 activity - are predictive of response to systemic therapy in patients with lung cancer.
- Trial name
- NCT02331290
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Hypothermia Due to Cold Environment
Characterization of Corticospinal Excitability During Progressive Skin Cooling
This study characterizes the changes in corticospinal excitability that accompany basic cold stress via skin cooling that result in reduced skin or core temperature and shivering.
- Trial name
- NCT04253730
- Testing
- Cold Stress
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Fracture Fixation, Internal, Metacarpal Fracture
The Effect of Forearm Nerve Blocks on Pain-free Tourniquet Time Compared to Local Anesthetic for Awake Hand Surgery
Wide-awake surgery with local anesthesia is a widely described approach to performing numerous minor hand procedures, such as tendon repairs and percutaneous fracture pinning, but is less frequently used for longer procedures…
- Conditions
- Fracture Fixation, Internal, Metacarpal Fracture, Finger Fracture, Anesthesia, Local
- Trial name
- NCT04787835
- Testing
- Forearm nerve block, Local anesthetic infiltration
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Hydrocele, Spermatocele
Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective Study
The goal of this observational study is to evaluate patient reported outcomes and tolerability of scrotal and penile urologic procedures under the administration of minimal conscious sedation.
- Conditions
- Hydrocele, Spermatocele, Varicocele, Epididymal Cyst
- Trial name
- NCT05617261
- Testing
- Conscious sedation
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Anxiety, Anxiety Disorders
Prazosin Use in Adults With Anxiety Disorders
Prazosin has shown effectiveness in treating Post-Traumatic Stress Disorder through improving sleep quality and global functioning.
- Trial name
- NCT03894345
- Testing
- Prazosin
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Intradialytic Hypotension, Hemodialysis-Induced Symptoms
Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension
The objective of this study is to compare the rate of low blood pressure events (Intradialytic Hypotension: IDH) when intradialytic exercise is performed in the first half of the hemodialysis (HD) session as compared to that when…
- Trial name
- NCT03504943
- Testing
- Early Intradialytic Exercise, Late Intradialytic Exercise
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- University of Manitoba
MEP Onset Latency
Deep Brain Stimulation (DBS) and Motor Evoked Potentials (MEP)
MEP onset latencies from the hand muscle using two different stimulus methods will be compared from each study participant. Conventional MEP data will be collected prior to skin incision.
- Trial name
- DBS MEP (NCT05569213)
- Testing
- motor evoked potentials
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Blood Glucose
A Pilot Study Evaluating Oat Polyphenols on Post-prandial Glucose Response
The trial will use a two period acute double-blind cross-over design to compare the effects of a serving of oatmeal containing high or low amounts of avenanthramides (AV) on post-prandial blood glucose response in healthy adults.
- Trial name
- NCT04260425
- Testing
- Serving of oatmeal made from low avenanthramides oats and water, Serving of oatmeal made from high avenanthramides oats and water
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Social Isolation, Loneliness
The CONNECT Program: Testing a Telephone-Based Mental Health Intervention for Older Adults
This study will test a telephone-based group intervention called "The CONNECT Program" which is designed for adults aged 65+ who are currently experiencing social isolation or loneliness, and symptoms of anxiety or depression.
- Conditions
- Social Isolation, Loneliness, Depression, Anxiety
- Trial name
- CONNECT (NCT05120765)
- Testing
- The CONNECT Program
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Perinatal Anxiety, Perinatal Depression
Evaluating Overcoming Anxiety in Pregnancy and Postpartum as an Online Self-Directed Program
The pregnancy and postpartum periods can be joyous times in life; however, they can also be filled with challenging physical, emotional, and lifestyle changes.
- Trial name
- NCT04844138
- Testing
- Overcoming Anxiety in Pregnancy and Postpartum Online Self-Directed Program
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Brain Injuries, Traumatic
Treatment and Recovery Monitoring of Post TBI Symptoms
This proposal aims to investigate the effect of a promising treatment for persistent post Traumatic Brain Injury (TBI) symptoms, and to monitor TBI patient's recovery by an objective technique along with standard clinical…
- Trial name
- NCT02426749
- Testing
- Active repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Blepharoptosis, Ptosis
Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair
Blepharoptosis (ptosis) repair is a common and generally well tolerated surgical procedure usually performed using local anesthetic.
- Trial name
- NCT02959697
- Testing
- Subcut. + Subconj. Xylocaine, Blepharoptosis Repair
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Chronic Pain
Pilot Study of Revised Online Chronic Pain Treatment for Military and Veterans
This study is being conducted to examine the efficacy of a revised version of an online chronic pain intervention tailored specifically for military, RCMP, and veterans.
- Trial name
- NCT05390957
- Testing
- Acceptance Based Behavioural Therapy - Revised
- Volunteers
- 34 people
- Sponsor
- University of Manitoba
Septic Shock, Vasodilatory Shock
Heparin Anticoagulation in Septic Shock
This study is a pragmatic open-label international randomized trial comparing therapeutic dose intravenous unfractionated heparin (UFH) to standard care venous thromboprophylaxis in patients diagnosed with septic shock.
- Trial name
- HALO (NCT03378466)
- Testing
- Unfractionated heparin, Venous thromboprophylaxis (VTE)
- Where
- 51 sites in United States, Brazil and 5 more
- Volunteers
- 178 people
- Sponsor
- University of Manitoba
Cancer, Cognitive Dysfunction
Feasibility and Acceptability of a Virtual 'Coping With Brain Fog' Intervention for Young Adults With Cancer
Cancer-related cognitive problems, also known as "brain fog", have a significant impact on patients with cancer and cancer survivors.
- Conditions
- Cancer, Cognitive Dysfunction, Cognitive Impairment, Adolescents
- Trial name
- NCT05115422
- Testing
- 'Coping with Brain Fog' program
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dementia, Viral Infection
Electronic Medical Records to Increase Adherence to the Choosing Wisely Recommendations
Audit and Feedback (A\&F), a strategy aimed at promoting modified practice through performance feedback, is a method to change provider behaviour and reduce unnecessary medical services.
- Conditions
- Dementia, Viral Infection, Vitamin D Deficiency
- Trial name
- NCT05385445
- Testing
- Audit and Feedback
- Where
- Canada
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Interstitial Lung Disease
Virtual Exercise Program in Interstitial Lung Disease (ILD) Patients
Design: this pilot-study uses a two-group random assignment pretest-posttest design. Once the groups are being selected an envelope will be mailed to the participant with the printed version of the exercise program and surveys, a…
- Trial name
- NCT04946708
- Testing
- Exercise program (virtual/remote)
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Parasomnia
Impact of Cognitive Behavioral Therapy on Parasomnias
This research aims to determine whether cognitive behavioral therapy can effectively reduce parasomnias in a sample of 20 adult outpatients with Non-REM and REM parasomnias.
- Trial name
- parasomnia (NCT04633668)
- Testing
- CBT for parasomnias (CBT-p), Self-Monitoring
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Cardiometabolic Syndrome, Weight Loss
Virtual Lifestyle Program Evaluation During Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
This is a pilot study evaluating an online cardiometabolic and weight loss program which is offered by The Wellness Institute. The program is 16 weeks and is developed by a multidisciplinary team and delivered by a degreed health…
- Trial name
- NCT04784624
- Testing
- Lifestyle program
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba