Clinical trials: sponsored by University of Manitoba
COVID-19, Pneumonia
Antithrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC)
Endothelial injury as a consequence of SARS-CoV-2 infection leads to a dysregulated host inflammatory response and activation of coagulation pathways.
- Trial name
- ATTACC (NCT04372589)
- Testing
- Heparin
- Where
- 60 sites in United States, Brazil and 2 more
- Volunteers
- 1,200 people
- Sponsor
- University of Manitoba
Obesity, Inflammation
Effects of Dietary Fatty Acids on Octadecanoid Production and Biological Actions in Obesity-induced Inflammation
This is a single site, double-blind, randomized, crossover study designed to compare the effects of dietary supplementation with flax oil rich in alpha-linolenic acid (ALA) and fish oil rich in docosahexaenoic acid (DHA) on…
- Trial name
- OXBIO (NCT03583281)
- Testing
- Capsules containing flax oil, Capsules containing DHA-enriched fish oil
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Depressive Symptoms, Anxiety Symptoms
The Acceptability and Effectiveness of Stepped Care Psychoeducation Classes in Rural Manitoba
This study will examine the acceptability and effectiveness of using a stepped care treatment model, and specifically, the CBTm classes, in a rural population.
- Trial name
- NCT04105790
- Testing
- Cognitive Behavioural Therapy with Mindfulness classes
- Where
- 2 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University of Manitoba
Maternal Depression
Building Emotional Awareness and Mental Health
Since its emergence in December 2019, COVID-19 has reshaped the world. Mental health problems are predicted to rise dramatically as a secondary effect of the disease and measures put in place to contain it.
- Trial name
- BEAM (NCT04772677)
- Testing
- BEAM Mental Health and Parenting Program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Heart Failure
The Effects of DVD Education on Physical Activity and Self Management of Heart Failure
The purpose of this research is to determine if there is a greater behaviour change in self management of heart failure following reinforced multimedia education focusing on physical activity as compared to standard care.
- Trial name
- NCT01622010
- Testing
- Allied Health Education Class Option, Physiotherapy treatment intervention on referral, Keeping the Beat with Physiotherapy: Heart Failure edition
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Total Knee Arthroplasty
The Health Impact of Mindfulness Based Stress Reduction on Total Knee Arthroplasty
Despite surgical success of total knee arthroplasty (TKA), reports of dissatisfaction and poor outcomes including increased pain, reduced function for daily activities, and compromised psychological health are common.
- Trial name
- NCT03228745
- Testing
- Pre-operative MBSR
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Spinal Cord Injuries, Spinal Cord Injury Cervical
Developing Strategies to Optimize the Exercise Response After Tetraplegia.
To identify means to improve exercise performance in participants with tetraplegia.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury Cervical, Paraplegia, Spinal
- Trial name
- NCT04465825
- Testing
- HITT: intermittent high intensity exercise
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Gambling Disorder
Effectiveness of an Online Integrated Treatment for Problem Gambling and Tobacco Smoking
Research has shown that problem gambling and tobacco smoking are highly comorbid. Problem gamblers who smoke tend to: have more severe gambling problems, experience stronger gambling urges, have other mental disorders, bet larger…
- Trial name
- NCT03614884
- Testing
- Gambling and Smoking Treatment, Gambling only treatment
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of Manitoba
Parkinson Disease
Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
The present proposal will evaluate the neural underpinnings of (a) the decline of mobility function in Parkinson's disease (PD), and (b) the effects of an innovative computer-guided dual-task (DT) mobility training platform…
- Trial name
- CMAGDT (NCT04415775)
- Testing
- Game based treadmill Program, Conventional Gait Rehabilitation
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Implant Site Bleeding
A Comparison of the Efficacy of Interdental Floss to Water Flosser Around Dental Implants
The primary objective of this study was to compare two different interproximal devices, water flosser and dental floss around implants in several clinical parameters
- Trial name
- NCT04081311
- Testing
- comparing interdental floss to water flosser around dental implants
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
PreDiabetes
Examining the Impact of a Self-compassion Intervention on Physical Activity Behaviour Among People With Prediabetes
The investigators plan to examine whether teaching people at risk for type two diabetes to use self-compassion (orientation to care for oneself during difficult situations) helps them self-manage and increase their physical…
- Trial name
- NCT04863235
- Testing
- Control Group, Intervention Group
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
PreDiabetes
Is Teaching People to be Self-compassionate Feasible and Acceptable for People Who Are Pre-diabetic
The investigators plan to examine the feasibility and acceptability of an online, two arm intervention ([self-compassion intervention + ideal care] versus [health information + ideal care]) designed to increase physical activity…
- Trial name
- NCT04402710
- Testing
- Self-compassion, Control Group
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Liver Cirrhosis, Ascites
Peritoneal Dialysis Catheters for the Treatment of Refractory Ascites
One complication of liver disease is the buildup of fluid within the belly. This is known as ascites. Patients who have ascites have a decreased appetite, pain, nausea and shortness of breath.
- Trial name
- NCT02975726
- Testing
- Peritoneal Dialysis Catheter, Large Volume Paracentesis, 25% Human Serum Albumin injection
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Obsessive Compulsive Disorder
Study of Magnetic Brain Stimulation in Treatment of Obsessive Compulsive Disorder
In a preliminary pilot study, the investigators tested the efficacy of rTMS over the medial prefrontal cortex in symptom profiles of obsessive compulsive disorder (OCD) patients.
- Trial name
- rTMS (NCT02018185)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Logopenic Progressive Aphasia
Can Magnetic Brain Stimulation Improve Language Function in Primary Progressive Aphasia
The purpose of this study is to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) - a form of non-invasive brain stimulation - to improve language functioning in individuals who have the…
- Trial name
- NCT04193267
- Testing
- MagStim Rapid2 Transcranial Magnetic Simulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Cancer
Acetylamantadine Excretion by Cancer Patients
Several factors discourage the implementation of cancer screening to the population in general, which would result in earlier diagnosis and an expected improved survival.
- Trial name
- NCT02277938
- Testing
- Amantadine
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Manitoba
Alcohol Use Disorder
Testing the Efficacy of an Online Integrated Treatment for Comorbid Alcohol Misuse and Emotional Problems
Considering the high comorbidity between alcohol use disorders and emotional problems, there is currently a need for accessible, integrated treatments designed to target both disorders simultaneously.
- Trial name
- NCT03406039
- Testing
- Integrated Online CBT and MI
- Where
- Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
COVID-19
Tele-monitoring of COVID-19 Survivors for Long-Term Impacts
To confront the COVID-19 pandemic hospitals need to maximize bed availability and minimize the duration of patients' stay as much as possible.
- Trial name
- NCT04644341
- Testing
- cardiovascular and respiratory systems monitoring
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Mild Cognitive Impairment, Alzheimer Dementia
Brain Fitness APP for Cognitive Enhancement
Memory and cognitive declines are associated with normal brain aging but are also precursors to dementia, in particular the so called the pandemic of the century, Alzheimer's disease.
- Trial name
- NCT03587012
- Testing
- Brain fitness app, Brain fitness app with tACS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Memory Problems
Brain Fitness APP for Aging With a Healthy Brain
Memory and cognitive declines are associated with normal brain aging but are also precursors to dementia, in particular the so called the pandemic of the century, Alzheimer's disease.
- Trial name
- NCT03600545
- Testing
- Brain Fitness App
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba