Clinical trials: sponsored by University of Manitoba
Type2 Diabetes Mellitus, Obesity
The Metabolic Impact of Bariatric Surgery Compared to Best Diabetic Care on Manitoba's Urban Indigenous Population
Obesity and type 2 diabetes mellitus (T2DM) are major global health concerns as they commonly co-occur and are associated with significant morbidity, mortality, and health care expenditures.
- Conditions
- Type2 Diabetes Mellitus, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT03301545
- Testing
- Fast-Track to Bariatric Surgery
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Lung Cancer, Atrial Fibrillation
Continuous Ambulatory ECG Monitoring for Detection of Postoperative Atrial Fibrillation Following Thoracic Surgery
Atrial fibrillation (AF) is a common and serious complication after lung resection. The incidence is likely underestimated, and risk may persist after leaving hospital.
- Trial name
- NCT04325269
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Parkinson Disease
Evaluating Effect of Cognitive Game Based Treadmill Exercise Program in Parkinson Disease
An inexpensive dual-task gait training protocol has been developed for people with PD namely game based treadmill platform. A feasibility randomized trial clinical trail will be conducted to evaluate the feasibility…
- Trial name
- NCT03835611
- Testing
- Game based treadmill Platform, Control Group
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Parkinson Disease, Parkinson
Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.
Examining the feasibility and acceptability of the computer game based rehabilitation system for improving balance, gait and executive function in individuals with PD.
- Trial name
- NCT03232996
- Testing
- Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Neoplasms
The Effects of a 6-week Balance, Agility, Strengthening Exercise Class
Cancer treatments can have a significant impact on a cancer survivor's function and independence, and these patients can have twice the incidence of falls than their cancer-free peers.
- Trial name
- NCT04318574
- Testing
- Balance, Agility, Strengthening Exercise (BASE) Class
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Spatial Navigation, Navigation, Spatial
Investigating the Effect of Training With a Virtual Reality Driving Simulator
The proposed study aims to investigate the use of a driving simulator in a virtual reality (VR) environment to improve the cognition state and spatial navigation of individuals with mild/moderate memory impairment.
- Conditions
- Spatial Navigation, Navigation, Spatial, Dementia
- Trial name
- NCT04074655
- Testing
- Driving Simulator in a Virtual Reality Environment
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dementia
A Mobile Application for Training of Family Caregivers Caring for Someone With Dementia
Background The mental, physical, and emotional health of caregivers is negatively affected by the burden of caring for of persons living with dementia.
- Trial name
- NCT04139707
- Testing
- Caring4Dementia, White Paper
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cerebral Desaturation, Cerebral Ischemia
Assessment of Cerebral Blood Flow Asymmetry in Cardiac Surgery Patients Undergoing Hypothermic Circulatory Arrest
Cerebral oxygen desaturation during cardiac surgery measured using near infrared spectroscopy (NIRS) derived cerebral oximetry has been associated with significant postoperative morbidity.
- Trial name
- COASTLINE (NCT03215589)
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anaerobic Exercise, Dietary Supplementations
Beetroot Juice Doses and Anaerobic Performance
The purpose of this study is to examine the effect of varying nitrate doses of beetroot juice supplementation on dynamic, multijoint resistance exercise performance in active, trained individuals.
- Trial name
- NCT02919254
- Testing
- Beet It Sport Shot
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Vocal Cord Paresis, Acquired Vocal Cord Palsy
The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery
Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients.
- Trial name
- NCT02996526
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- University of Manitoba
Trained or Competitive Cyclists
Beet Root Supplement Trial
To examine the effects of two forms of beetroot juice supplementation on exercise performance in trained cyclists.
- Trial name
- NCT02010502
- Testing
- Beetroot juice, Beetroot powder
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sitosterolemia
Sitosterolemia Metabolism
Ezetimibe has become the treatment choice for patients with sitosterolemia. Ezetimibe is an inhibitor of cholesterol absorption from the gastrointestinal tract.
- Trial name
- STAIR7002 (NCT01584206)
- Testing
- Ezetimibe
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cognitive Impairment, Psychosis
Action-based Cognitive Remediation for First Episode Psychosis
Cognitive impairments are a core and enduring feature of first-episode psychosis and schizophrenia, and are associated with significant functional impairment.
- Trial name
- NCT03814122
- Testing
- Action-based cognitive remediation, Waitlist Control Group
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Liver Failure
Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants
Background: Previous studies have documented differences in the pharmacokinetics (PK) of a once daily FK506 formulation (Advagraf) based on patient ethnicity.
- Trial name
- NCT04237246
- Testing
- Tacrolimus
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Vaccine Hesitancy
Public Health Messages to Address Vaccine Hesitancy
Views on vaccines range from those who are strongly supportive to those who are stridently opposed and will not budge from identity-based core beliefs about vaccines.
- Trial name
- NCT03395106
- Testing
- Parent source, Doctor source, Deliberative content
- Where
- Canada
- Volunteers
- 883 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
HIV
Inducing Immune Quiescence to Prevent HIV Infection in Women
In this project, the investigators want to analyse the capacity of Acetylsalicylic acid and hydoxychlroquin (HCQ) to induce an Immune Quiescence (IQ) phenotype, which has been previously associated with natural protection to HIV…
- Trial name
- IIQ (NCT02079077)
- Testing
- Acetylsalicylic Acid (ASA), Hydroxychloroquine (HCQ)
- Where
- Kenya
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Frail Elderly
Increasing the Winter Community Participation of Older Adult Wheelchair Users
The purpose of this study is to examine whether intervention strategies targeted at the level of the environment (e.g. improving access to community based leisure groups, transportation) can successfully promote the community…
- Trial name
- NCT02622828
- Testing
- Participant-identified community based activity
- Where
- Canada
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Fractures, Bone, Fracture Complications
Comparison of the Safety and Cost of a Simplified Post-Operative Radiograph (SPOR) Protocol
The standard post-operative radiographic protocol for the monitoring of fractures at Health Sciences Centre includes post-operative in hospital radiographs as well as radiographs at the two week follow up appointment.
- Conditions
- Fractures, Bone, Fracture Complications, Xray Complication
- Trial name
- SPOR (NCT04110470)
- Testing
- X-ray, No-Xray
- Volunteers
- 1,612 people
- Sponsor
- University of Manitoba
Periodontitis
Efficacy of Adjunctive Antimicrobial Photodynamic Therapy for Residual Pockets in Previously Surgically Treated Teeth
Traditionally, periodontal gum surgery has been used as a method to gain access to inflamed periodontal pockets around teeth. The outcome of these surgeries, however, is not always successful as there can be recurrence of…
- Trial name
- NCT03757260
- Testing
- Antimicrobial photodynamic therapy
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Very Low Birth Weight Baby, Premature Birth
Human-derived Human Milk Fortifiers (H2MF), Gut Microbiota and Oxidative Stress in Premature Infants
This is a randomized controlled trial of a human-derived human milk fortifier (H2MF) vs standard bovine-derived human milk fortifier (HMF) evaluating fecal microbiota and fecal and urinary biomarkers of oxidative stress in…
- Conditions
- Very Low Birth Weight Baby, Premature Birth, Microbial Colonization, Oxidative Stress
- Trial name
- NCT03214822
- Testing
- H2MF
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba