Clinical trials: sponsored by University of Manitoba
Influenza A Virus Infection, Influenza B Virus Infection
Study of the Relative Oral Bioavailability of the Antiflu Medicine Oseltamivir in the Intensive Care Unit
This proposed pharmacokinetic study will test the hypothesis that in critically ill patients with respiratory failure requiring mechanical ventilation such as might be anticipated to be needed to treat patients with severe…
- Trial name
- NCT00844155
- Testing
- Oseltamivir 75 mg
- Where
- Canada
- Sponsor
- University of Manitoba
Sleep Apnea Syndromes
Cycloserine in the Treatment of Sleep Apnea
This study is being conducted to determine whether cycloserine is effective for the treatment of sleep apnea. Cycloserine is an antibiotic that has been extensively used in the treatment tuberculosis.
- Trial name
- NCT02735694
- Testing
- Cycloserine
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Manitoba
Surface Roughness, Maintenance of Dental Implants
Comparison of the Effect of Teflon vs Non-Teflon Hand Scalers in the Maintenance of Peri-Implant Tissue
The buccal and lingual surface of the 23 participants' crowns will be randomly assigned to receive scaling and root planing with either Teflon scalers, or non-Teflon scalers after implant crown delivery.
- Conditions
- Surface Roughness, Maintenance of Dental Implants, Inflammation
- Trial name
- NCT03316937
- Testing
- Types of scalers
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Diseases, Cardiovascular Risk Factor
An Urban Trail Network and Cardiovascular Disease: A Natural Experiment
Associations between the built environment and health behaviours are robust, however (1) it remains unclear if the behaviours they elicit lead to meaningful improvements in health outcomes, at the population level and (2) little…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Diabetes Mellitus
- Trial name
- NCT04057417
- Testing
- Urban Trail
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Bronchopulmonary Dysplasia, Respiratory Distress Syndrome in Premature Infant
Budesonide With Intratracheal Surfactants in Extremely Preterm Infants
This is a phase I/II trial in preterm infants aimed at identifying the optimal dose of budesonide with bovine lipid extract surfactant as vehicle for intratracheal administration.
- Trial name
- BITS (NCT04019106)
- Testing
- Budesonide in bovine lipid extract surfactant (BLES)
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Postoperative Delirium
An MRI Study of Post-operative Delirium in Patients Undergoing Major Surgery
Hypothesis: Patients with blue cerebrovascular reactivity (CVR) regional maps during a hypercapnic CO2 challenge will be at greater risk of developing post-operative delirium (POD) and stroke following major surgery.
- Trial name
- NCT02126215
- Testing
- MRI CO2 and O2 stress testing
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Diabetes Mellitus, Type 1
Mindful Self-Compassion to Assist Emerging Adults With Diabetes Transition to Adulthood
The transition from pediatric to adult care is particularly difficult for individuals with Type 1 diabetes. It is hypothesized that a mindfulness-based intervention for individuals making this transition will contribute to…
- Trial name
- NCT03999385
- Testing
- Mindful Self-Compassion (MSC)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Emotional Stress, Work Related Illnesses
A Mindfulness Based Intervention as a Key Component of Successful Workplace Functioning and Personal Well-being
This study will evaluate the effectiveness of an 8-week program in Mindfulness-Based Stress Reduction (MBSR) in reducing work absences and improving the well-being of healthcare workers.
- Conditions
- Emotional Stress, Work Related Illnesses, Burnout, Professional, Burnout Syndrome
- Trial name
- NCT03969771
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Breast Diseases
Performance Assessment of a First Generation Breast Microwave Imaging System: Study of Breast Abnormalities Detection
The main goal of this project is to assess the ability of a recently developed Breast Microwave Imaging (BMI) system to detect abnormalities in a human breast.
- Trial name
- NCT02566499
- Testing
- Breast Microwave Imaging
- Sponsor
- University of Manitoba
Acquired Brain Injury
Outcomes Following Neuropsychological Intervention in Acquired Brain Injury Outpatients With Executive Dysfunction
This Clinical Trial is a pilot study being conducted to study the impact of a specific cognitive rehabilitation program, Goal Management Training (GMT), in adult patients with executive dysfunction and associated problems in…
- Trial name
- NCT01992055
- Testing
- Goal Management Training, Education & relaxation training
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Manitoba
Suicidal Ideation
The Effectiveness of Psychotherapy Classes in Reducing Suicidal Ideation
The proposed study will conduct a preliminary investigation of the effectiveness of two different psychotherapy classes at the Mental Health Crisis Response Centre (CRC) in reducing suicidal ideation.
- Trial name
- NCT03170934
- Testing
- Psychotherapy skills class
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- University of Manitoba
Pain, Postoperative, Shoulder Joint Disorder
Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
In this single-centre, double-blinded, randomized controlled superiority trial, 189 participants having outpatient, arthroscopic shoulder surgery will be randomized into 3 equal sized groups.
- Conditions
- Pain, Postoperative, Shoulder Joint Disorder, Ambulatory Surgical Procedures, Brachial Plexus Block
- Trial name
- NCT03270033
- Testing
- Dexamethasone, Dexmedetomidine
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- University of Manitoba
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Stroke
Upper Extremity Recovery Post Stroke Using Virtual Occupations
The purpose of this study is to explore the efficacy of the SaeboVR rehabilitation system for improving functional outcomes related to upper extremity motor recovery in stroke survivors. The specific objectives are: 1.
- Trial name
- NCT03886480
- Testing
- SaeboVR
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Cerebral Palsy
Innovative Game-Aided Rehabilitation Platform for Rehabilitation of Balance in Children With Cerebral Palsy
The research project focuses on the evaluation of an engaging computer game-aided rehabilitation platform for use in rehabilitation of young children with cerebral palsy.
- Trial name
- NCT03873441
- Testing
- Computer Games-Aided Balance Training Protocol, Conventional Balance Training Protocol
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Impaired Glucose Tolerance
Effects of Artificial Sweeteners on Gut Microbiota and Glucose Metabolism
The Objectives of this study is to determine the effect(s) of daily non-caloric artificial sweetener (NAS) consumption (sucralose or aspartame) on the composition of the bacteria and also to determine the changes in glucose…
- Trial name
- NCT02569762
- Testing
- Sucralose-Aspartame, Aspartame-Sucralose
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypothermia
Head and Torso Rewarming Using a Human Model for Severe Hypothermia
This Clinical trial is being conducted to study the effectiveness of heat donation through head or torso in hypothermic rewarming efficacy using a human model for severe hypothermia.
- Trial name
- NCT02685176
- Testing
- Charcoal Heater (STK Heatpac, Emergco Tech Solutions, B.C.), No heat
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypertension
Double-Blind, Randomized, Cross-Over Trial of Aged Garlic Extract for Hypertension
The primary objective of this trial is to assess the effect of consumption of aged garlic extract powder on 24 h systolic and diastolic ambulatory blood pressure in hypertensive individuals following 8 weeks of supplementation.
- Trial name
- NCT03211767
- Testing
- Aged garlic extract
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Manitoba
Coping Behavior, Emotional Distress
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
The Creative Arts Diabetes Initiative will offer facilitated art therapy with a group/peer-support environment to two groups of youth/young adults, one with type 1 diabetes, and one with type 2 diabetes.
- Conditions
- Coping Behavior, Emotional Distress, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- CADI (NCT02790892)
- Testing
- Art therapy - pre and post test measures
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Obesity
The Impact of a Pre-Operative Exercise Program on Fitness Outcomes Following Bariatric Surgery
BACKGROUND: Obesity is a global epidemic and Canada has one of the highest obesity rates in westernized countries. Obesity has many health related complications, including high blood pressure, high cholesterol, diabetes, sleep…
- Trial name
- NCT02010489
- Testing
- 12 week Exercise Program
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Manitoba